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Namespace Prefixes

Prefix	IRI
n5	http://linked.opendata.cz/resource/mesh/concept/
rdfs	http://www.w3.org/2000/01/rdf-schema#
n6	http://linked.opendata.cz/resource/fda-spl/ingredient/
rdf	http://www.w3.org/1999/02/22-rdf-syntax-ns#
n4	http://linked.opendata.cz/ontology/mesh/
owl	http://www.w3.org/2002/07/owl#
nci	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#
xsdh	http://www.w3.org/2001/XMLSchema#

Statements

Subject Item: nci:C1702
rdf:type: owl:Class
rdfs:label: Rituximab
owl:equivalentClass: _:vb638133
nci:A7: nci:C38896
nci:A8: nci:C63923
nci:P106: Amino Acid, Peptide, or Protein Immunologic Factor
nci:P108: Rituximab
nci:P175: 687451
nci:P207: C0732355
nci:P210: 174722-31-7
nci:P302: Diffuse Large B-cell, CD20-positive, Non-Hodgkins Lymphoma
nci:P303: Non-Hodgkins lymphoma; indolent follicular lymphoma; chronic lymphocytic leukemia, or other B-cell tumors; progressive large cell lymphoma; acute lymphoblastic leukemia; central nervous system lymphoma
nci:P319: 4F4X42SYQ6
nci:P322: FDA
nci:P325: <n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A drug used to treat certain types of B-cell non-Hodgkin lymphoma. It is also used with other drugs to treat chronic lymphocytic leukemia and rheumatoid arthritis. It is being studied in the treatment of other types of cancer and other conditions. Rituximab binds to a protein called CD20, which is found on B-cells, and may kill cancer cells. It is a type of monoclonal antibody.</n0:def-definition><n0:def-source>NCI-GLOSS</n0:def-source></n0:ComplexDefinition>
nci:P329: 42613
nci:P330: 42613
nci:P366: Rituximab
nci:P368: CHEBI:64357
nci:P90: <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>IDEC-102</n0:term-name><n0:term-group>CN</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>C2B8 Monoclonal Antibody</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Rituxan</n0:term-name><n0:term-group>BR</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>IDEC-C2B8</n0:term-name><n0:term-group>CN</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Monoclonal Antibody IDEC-C2B8</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Rituximab</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Rituxan</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI-GLOSS</n0:term-source><n0:source-code>CDR0000505945</n0:source-code></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>RITUXIMAB</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>FDA</n0:term-source><n0:source-code>4F4X42SYQ6</n0:source-code></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Rituximab</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source><n0:source-code>TCGA</n0:source-code></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Chimeric Anti-CD20 Antibody</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>MabThera</n0:term-name><n0:term-group>FB</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>rituximab</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI-GLOSS</n0:term-source><n0:source-code>CDR0000045525</n0:source-code></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>IDEC-C2B8 Monoclonal Antibody</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
nci:P97: <n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A recombinant chimeric murine/human antibody directed against the CD20 antigen, a hydrophobic transmembrane protein located on normal pre-B and mature B lymphocytes. Following binding, rituximab triggers a host cytotoxic immune response against CD20-positive cells. (NCI04)</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>
nci:code: C1702
owl:sameAs: n6:4F4X42SYQ6
n4:hasConcept: n5:M0244306

Subject Item: _:vb638133
rdf:type: owl:Class
owl:intersectionOf: _:vb733657

Subject Item: _:vb709406
rdf:type: owl:Restriction
owl:onProperty: nci:R72
owl:someValuesFrom: nci:C12474

Subject Item: _:vb709407
rdf:type: owl:Restriction
owl:onProperty: nci:R72
owl:someValuesFrom: nci:C12543

Subject Item: _:vb709408
rdf:type: owl:Restriction
owl:onProperty: nci:R146
owl:someValuesFrom: nci:C38896

Subject Item: _:vb709409
rdf:type: owl:Restriction
owl:onProperty: nci:R124
owl:someValuesFrom: nci:C40474

Subject Item: _:vb709410
rdf:type: owl:Restriction
owl:onProperty: nci:R125
owl:someValuesFrom: nci:C19053

Subject Item: _:vb733657
rdf:first: nci:C20401
rdf:rest: _:vb785607

Subject Item: _:vb785607
rdf:first: _:vb709406
rdf:rest: _:vb785608

Subject Item: _:vb785608
rdf:first: _:vb709407
rdf:rest: _:vb785609

Subject Item: _:vb785609
rdf:first: _:vb709408
rdf:rest: _:vb785610

Subject Item: _:vb785610
rdf:first: _:vb709409
rdf:rest: _:vb785611

Subject Item: _:vb785611
rdf:first: _:vb709410
rdf:rest: rdf:nil