This HTML5 document contains 65 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
n7http://linked.opendata.cz/resource/mesh/concept/
rdfshttp://www.w3.org/2000/01/rdf-schema#
n5http://linked.opendata.cz/resource/fda-spl/ingredient/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n6http://linked.opendata.cz/ontology/mesh/
owlhttp://www.w3.org/2002/07/owl#
ncihttp://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#
xsdhhttp://www.w3.org/2001/XMLSchema#

Statements

Subject Item
nci:C1440
rdf:type
owl:Class
rdfs:label
Sodium Phenylbutyrate
owl:equivalentClass
_:vb641408
nci:A7
nci:C16682
nci:A8
nci:C63923
nci:P106
Lipid Pharmacologic Substance
nci:P108
Sodium Phenylbutyrate
nci:P175
657802
nci:P207
C0718066
nci:P210
1716-12-7
nci:P302
Adjunctive therapy for urea cycle disorders involving deficiencies of carbamoylphosphate synthetase; ornithine transcarbamylase; or argininosuccinic acid synthetase; S-S and S-C sickle cell disease; S-thalassemia hemoglobinopathy
nci:P303
Refractory solid tumors; myelodysplastic syndromes; chronic myelomonocytic leukemia; acute myeloid leukemia; advanced colorectal adenocarcinoma
nci:P319
NT6K61736T
nci:P322
FDA
nci:P325
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called differentiating agents.</n0:def-definition><n0:def-source>NCI-GLOSS</n0:def-source></n0:ComplexDefinition>
nci:P329
536018
nci:P330
536018
nci:P350
C10H11O2.Na
nci:P366
_4-Phenylbutyrate
nci:P90
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Sodium 4-phenylbutyrate</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>DTP</n0:term-source><n0:source-code>NSC0657802</n0:source-code></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>SPB11</n0:term-name><n0:term-group>BR</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>SODIUM PHENYLBUTYRATE</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>FDA</n0:term-source><n0:source-code>NT6K61736T</n0:source-code></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Sodium Phenylbutyrate</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>DCP</n0:term-source><n0:source-code>31743</n0:source-code></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>phenylbutyrate</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI-GLOSS</n0:term-source><n0:source-code>CDR0000045402</n0:source-code></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Sodium 4-Phenylbutyrate</n0:term-name><n0:term-group>SN</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Phenylbutyrate Sodium</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Buphenyl</n0:term-name><n0:term-group>BR</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Sodium Phenylbutyrate</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>4-Phenylbutyric Acid, Sodium Salt</n0:term-name><n0:term-group>SN</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
nci:P97
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>The sodium salt of phenylbutyrate, a derivative of the short-chain fatty acid butyrate, with potential antineoplastic activity. Phenylbutyrate reversibly inhibits class I and II histone deacetylases (HDACs), which may result in a global increase in gene expression, decreased cellular proliferation, increased cell differentiation, and the induction of apoptosis in susceptible tumor cell populations.</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>
nci:code
C1440
owl:sameAs
n5:NT6K61736T
n6:hasConcept
n7:M0325828
Subject Item
_:vb641408
rdf:type
owl:Class
owl:intersectionOf
_:vb740165
Subject Item
_:vb725198
rdf:type
owl:Restriction
owl:onProperty
nci:R146
owl:someValuesFrom
nci:C16682
Subject Item
_:vb725199
rdf:type
owl:Restriction
owl:onProperty
nci:R124
owl:someValuesFrom
nci:C40577
Subject Item
_:vb725200
rdf:type
owl:Restriction
owl:onProperty
nci:R125
owl:someValuesFrom
nci:C25830
Subject Item
_:vb725201
rdf:type
owl:Restriction
owl:onProperty
nci:R125
owl:someValuesFrom
nci:C40664
Subject Item
_:vb725202
rdf:type
owl:Restriction
owl:onProperty
nci:R125
owl:someValuesFrom
nci:C21050
Subject Item
_:vb728914
rdf:first
nci:C1946
rdf:rest
_:vb796249
Subject Item
_:vb740165
rdf:first
nci:C492
rdf:rest
_:vb728914
Subject Item
_:vb796249
rdf:first
_:vb725198
rdf:rest
_:vb796250
Subject Item
_:vb796250
rdf:first
_:vb725199
rdf:rest
_:vb796251
Subject Item
_:vb796251
rdf:first
_:vb725200
rdf:rest
_:vb796252
Subject Item
_:vb796252
rdf:first
_:vb725201
rdf:rest
_:vb796253
Subject Item
_:vb796253
rdf:first
_:vb725202
rdf:rest
rdf:nil