SPARQL | HTML Microdata document This HTML5 document contains 29 embedded RDF statements represented using HTML+Microdata notation.
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Namespace Prefixes
Prefix IRI n6 http://linked.opendata.cz/resource/mesh/concept/ rdfs http://www.w3.org/2000/01/rdf-schema# rdf http://www.w3.org/1999/02/22-rdf-syntax-ns# n5 http://linked.opendata.cz/ontology/mesh/ owl http://www.w3.org/2002/07/owl# nci http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl# n4 http://linked.opendata.cz/resource/ndfrt/ingredient/ xsdh http://www.w3.org/2001/XMLSchema#
Statements
Subject Item nci:C1399
rdf:type
owl:Class
rdfs:label
Peplomycin
rdfs:subClassOf
nci:C2311
nci:A5
nci:C1400
nci:A8
nci:C63923
nci:P106
Amino Acid, Peptide, or Protein
Antibiotic
nci:P108
Peplomycin
nci:P175
276382
nci:P207
C0135981
nci:P210
68247-85-8
nci:P319
56H9L80NIZ
nci:P322
FDA
nci:P325
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>An antineoplastic agent derived from BLEOMYCIN.</n0:def-definition><n0:def-source>MSH2002_06_01</n0:def-source></n0:ComplexDefinition>
nci:P329
39552
nci:P330
39552
nci:P350
C61H88N18O21S2
nci:P366
Peplomycin
nci:P90
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>(S)-n1-[3-[(1-phenylethyl)amino]propyl]bleomycinamide</n0:term-name><n0:term-group>SN</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>PEPLOMYCIN</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>FDA</n0:term-source><n0:source-code>56H9L80NIZ</n0:source-code></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>PEPLEOMYCIN</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>DTP</n0:term-source><n0:source-code>NSC0276382</n0:source-code></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Peplomycin</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>n1-[3[[(S)-alpha-methylbenzyl]amino]propyl]bleomycinamide</n0:term-name><n0:term-group>SN</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Pepleomycin</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>PEP</n0:term-name><n0:term-group>AB</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
nci:P97
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A semisynthetic analog of Bleomycin, a mixture of several basic glycopeptide antineoplastic antibiotics isolated from Streptomyces verticillus. Peplomycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals that cause single- and double-stranded breaks in DNA. This agent appears to show greater antitumor activity than bleomycin; its use is limited due to pulmonary toxicity. (NCI04)</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>
nci:code
C1399
owl:sameAs
n4:N0000170300
n5:hasConcept
n6:M0026717