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Namespace Prefixes

Prefix	IRI
n6	http://linked.opendata.cz/resource/mesh/concept/
rdfs	http://www.w3.org/2000/01/rdf-schema#
rdf	http://www.w3.org/1999/02/22-rdf-syntax-ns#
n5	http://linked.opendata.cz/ontology/mesh/
owl	http://www.w3.org/2002/07/owl#
nci	http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#
xsdh	http://www.w3.org/2001/XMLSchema#

Statements

Subject Item

nci:C101052

rdf:type

owl:Class

rdfs:label

CBFB/MYH11 Fusion Protein

rdfs:subClassOf

_:vb652652 _:vb652651 nci:C17561

nci:P106

Amino Acid, Peptide, or Protein

nci:P108

CBFB/MYH11 Fusion Protein

nci:P207

C0381246

nci:P90

<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>CBFbeta/SMMHC Fusion Protein</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>CBFB/MYH11 Fusion Protein</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>CBFbeta-MYH11 Fusion Protein</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Core-Binding Factor Subunit Beta/Myosin-11 Fusion Protein</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>CBFbeta-SMMHC Fusion Protein</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>CBFb-MYH11 Fusion Protein</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>

nci:P97

<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A fusion protein encoded by the CBFB/MYH11 fusion gene. This protein is comprised of most of the core-binding factor subunit beta fused to the C-terminal dimerization domain of myosin-11.</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>

nci:P98

The CBFB/MYH11 fusion protein appears to act as a dominant-negative for the transcriptional activation activity mediated by the intact core-binding factor subunit beta protein.

nci:code

C101052

n5:hasConcept

n6:M0251508

Subject Item

_:vb652651

rdf:type

owl:Restriction

owl:onProperty

nci:R54

owl:someValuesFrom

nci:C101051

Subject Item

_:vb652652

rdf:type

owl:Restriction

owl:onProperty

nci:R53

owl:someValuesFrom

nci:C16521