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Namespace Prefixes

PrefixIRI
n8http://linked.opendata.cz/resource/mesh/concept/
rdfshttp://www.w3.org/2000/01/rdf-schema#
n5http://linked.opendata.cz/resource/fda-spl/ingredient/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n7http://linked.opendata.cz/ontology/mesh/
owlhttp://www.w3.org/2002/07/owl#
ncihttp://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#
n6http://linked.opendata.cz/resource/ndfrt/ingredient/
xsdhhttp://www.w3.org/2001/XMLSchema#

Statements

Subject Item
nci:C1005
rdf:type
owl:Class
rdfs:label
Arsenic Trioxide
owl:equivalentClass
_:vb629722
nci:A7
nci:C53622
nci:A8
nci:C63923
nci:P106
Inorganic Chemical Pharmacologic Substance
nci:P108
Arsenic Trioxide
nci:P175
706363
nci:P207
C0052416
nci:P210
1327-53-3
nci:P302
Myelodysplastic syndrome; multiple myeloma; chronic myeloid leukemia; acute myelocytic leukemia
nci:P303
Advanced neuroblastoma or other pediatric solid tumors; metastatic stage IVA or IVB hormone-refractory prostate cancer; myelodysplastic syndromes Refractory leukemia or lymphoma; resistant chronic phase chronic myelogenous leukemia; acute promyelocytic leukemia; recurrent or refractory multiple myeloma; locally advanced or metastatic non-small cell lung cancer Locally advanced or metastatic breast cancer; refractory testicular or extragonadal germ cell malignancies; refractory adenocarcinoma of the pancreas; advanced adenocarcinoma of the esophagus or gastroesophageal junction
nci:P319
S7V92P67HO
nci:P322
FDA
nci:P325
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A drug used to treat acute promyelocytic leukemia (APL) that has not gotten better or that has come back after treatment with other anticancer drugs. It is also being studied in the treatment of other types of cancer.</n0:def-definition><n0:def-source>NCI-GLOSS</n0:def-source></n0:ComplexDefinition>
nci:P329
43067
nci:P330
43067
nci:P350
As2O3
nci:P366
Arsenic_Trioxide
nci:P368
CHEBI:30621
nci:P90
<n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Trisenox</n0:term-name><n0:term-group>BR</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Arsenous Oxide</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>arsenic trioxide</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI-GLOSS</n0:term-source><n0:source-code>CDR0000046018</n0:source-code></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Trisenox</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI-GLOSS</n0:term-source><n0:source-code>CDR0000523452</n0:source-code></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Arsenic (III) Oxide</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Arsenic Sesquioxide</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Arsenous Acid</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Arsenous Acid Anhydride</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>ARSENIC TRIOXIDE</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>FDA</n0:term-source><n0:source-code>S7V92P67HO</n0:source-code></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>White Arsenic</n0:term-name><n0:term-group>SY</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm> <n0:ComplexTerm xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:term-name>Arsenic Trioxide</n0:term-name><n0:term-group>PT</n0:term-group><n0:term-source>NCI</n0:term-source></n0:ComplexTerm>
nci:P97
<n0:ComplexDefinition xmlns:n0="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><n0:def-definition>A small-molecule arsenic compound with antineoplastic activity. The mechanism of action of arsenic trioxide is not completely understood. This agent causes damage to or degradation of the promyelocytic leukemia protein/retinoic acid receptor-alpha (PML/RARa) fusion protein; induces apoptosis in acute promyelocytic leukemia (APL) cells and in many other tumor cell types; promotes cell differentiation and suppresses cell proliferation in many different tumor cell types; and is pro-angiogenic. (NCI04)</n0:def-definition><n0:def-source>NCI</n0:def-source></n0:ComplexDefinition>
nci:code
C1005
owl:sameAs
n5:S7V92P67HO n6:N0000179044
n7:hasConcept
n8:M0049263
Subject Item
_:vb629722
rdf:type
owl:Class
owl:intersectionOf
_:vb738556
Subject Item
_:vb646665
rdf:type
owl:Restriction
owl:onProperty
nci:R72
owl:someValuesFrom
nci:C13258
Subject Item
_:vb646666
rdf:type
owl:Restriction
owl:onProperty
nci:R124
owl:someValuesFrom
nci:C40551
Subject Item
_:vb646667
rdf:type
owl:Restriction
owl:onProperty
nci:R125
owl:someValuesFrom
nci:C17932
Subject Item
_:vb646668
rdf:type
owl:Restriction
owl:onProperty
nci:R125
owl:someValuesFrom
nci:C17557
Subject Item
_:vb646669
rdf:type
owl:Restriction
owl:onProperty
nci:R125
owl:someValuesFrom
nci:C40738
Subject Item
_:vb738556
rdf:first
nci:C1934
rdf:rest
_:vb748722
Subject Item
_:vb748722
rdf:first
_:vb646665
rdf:rest
_:vb748723
Subject Item
_:vb748723
rdf:first
_:vb646666
rdf:rest
_:vb748724
Subject Item
_:vb748724
rdf:first
_:vb646667
rdf:rest
_:vb748725
Subject Item
_:vb748725
rdf:first
_:vb646668
rdf:rest
_:vb748726
Subject Item
_:vb748726
rdf:first
_:vb646669
rdf:rest
rdf:nil