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Namespace Prefixes

PrefixIRI
n16http://linked.opendata.cz/resource/drugbank/drug/DB06709/identifier/pharmgkb/
n2http://linked.opendata.cz/resource/drugbank/drug/
dctermshttp://purl.org/dc/terms/
n7http://linked.opendata.cz/resource/drugbank/drug/DB06709/identifier/kegg-compound/
n10http://linked.opendata.cz/resource/drugbank/drug/DB06709/identifier/pubchem-compound/
n13http://linked.opendata.cz/resource/drugbank/dosage/
n6http://linked.opendata.cz/resource/drugbank/drug/DB06709/identifier/pubchem-substance/
n12http://linked.opendata.cz/resource/drugbank/drug/DB06709/identifier/drugbank/
n9http://bio2rdf.org/drugbank:
admshttp://www.w3.org/ns/adms#
n14http://wifo5-03.informatik.uni-mannheim.de/drugbank/resource/drugs/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
owlhttp://www.w3.org/2002/07/owl#
n3http://linked.opendata.cz/ontology/drugbank/
n4http://linked.opendata.cz/resource/drugbank/property/
n11http://linked.opendata.cz/resource/drugbank/drug/DB06709/identifier/chebi/
xsdhhttp://www.w3.org/2001/XMLSchema#
n17http://linked.opendata.cz/resource/drugbank/drug/DB06709/identifier/wikipedia/

Statements

Subject Item
n2:DB06709
rdf:type
n3:Drug
n3:description
Methacholine acts as a non-selective muscarinic receptor agonist to stimulate the parasympathetic nervous system. It is most commonly used for diagnosing bronchial hyperreactivity, using the bronchial challenge test. Through this test, the drug causes bronchoconstriction and people with pre-existing airway hyperreactivity, such as asthmatics, will react to lower doses of drug.
n3:dosage
n13:271B5041-363D-11E5-9242-09173F13E4C5
n3:group
approved
n3:indication
It is most commonly used for diagnosing bronchial hyperreactivity, using the bronchial challenge test.
owl:sameAs
n9:DB06709 n14:DB06709
dcterms:title
Methacholine
adms:identifier
n6:99443261 n7:C07471 n10:1993 n11:6804 n12:DB06709 n16:PA165958382 n17:Methacholine
n3:mechanismOfAction
By agonizing the muscarinic receptors, this drug induces bronchoconstriction. This bronchoconstriction is used as a test in asthmatics and in bronchial hyperreactivity.
n3:synonym
Methacholine MCh Acetyl-beta-methylcholine Acetylmethylcholine
n3:IUPAC-Name
n4:271B5046-363D-11E5-9242-09173F13E4C5
n3:InChI
n4:271B504C-363D-11E5-9242-09173F13E4C5
n3:Molecular-Formula
n4:271B504B-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n4:271B5048-363D-11E5-9242-09173F13E4C5
n3:Monoisotopic-Weight
n4:271B5049-363D-11E5-9242-09173F13E4C5
n3:SMILES
n4:271B504A-363D-11E5-9242-09173F13E4C5
n3:Water-Solubility
n4:271B5044-363D-11E5-9242-09173F13E4C5
n3:logP
n4:271B5042-363D-11E5-9242-09173F13E4C5 n4:271B5045-363D-11E5-9242-09173F13E4C5
n3:logS
n4:271B5043-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Acceptor-Count
n4:271B5052-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Donor-Count
n4:271B5053-363D-11E5-9242-09173F13E4C5
n3:InChIKey
n4:271B504D-363D-11E5-9242-09173F13E4C5
n3:Polar-Surface-Area--PSA-
n4:271B504E-363D-11E5-9242-09173F13E4C5
n3:Polarizability
n4:271B5050-363D-11E5-9242-09173F13E4C5
n3:Refractivity
n4:271B504F-363D-11E5-9242-09173F13E4C5
n3:Rotatable-Bond-Count
n4:271B5051-363D-11E5-9242-09173F13E4C5
n3:casRegistryNumber
55-92-5
n3:Bioavailability
n4:271B5057-363D-11E5-9242-09173F13E4C5
n3:Ghose-Filter
n4:271B5059-363D-11E5-9242-09173F13E4C5
n3:MDDR-Like-Rule
n4:271B505A-363D-11E5-9242-09173F13E4C5
n3:Number-of-Rings
n4:271B5056-363D-11E5-9242-09173F13E4C5
n3:Physiological-Charge
n4:271B5055-363D-11E5-9242-09173F13E4C5
n3:Rule-of-Five
n4:271B5058-363D-11E5-9242-09173F13E4C5
n3:Traditional-IUPAC-Name
n4:271B5047-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-basic-
n4:271B5054-363D-11E5-9242-09173F13E4C5