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Namespace Prefixes

PrefixIRI
n2http://linked.opendata.cz/resource/drugbank/drug/
dctermshttp://purl.org/dc/terms/
n8http://linked.opendata.cz/resource/drugbank/drug/DB05791/identifier/chemspider/
n9http://linked.opendata.cz/resource/drugbank/drug/DB05791/identifier/wikipedia/
n12http://bio2rdf.org/drugbank:
admshttp://www.w3.org/ns/adms#
n7http://linked.opendata.cz/resource/drugbank/drug/DB05791/identifier/pubchem-compound/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
owlhttp://www.w3.org/2002/07/owl#
n3http://linked.opendata.cz/ontology/drugbank/
n6http://linked.opendata.cz/resource/drugbank/drug/DB05791/identifier/drugbank/
n4http://linked.opendata.cz/resource/drugbank/property/
xsdhhttp://www.w3.org/2001/XMLSchema#

Statements

Subject Item
n2:DB05791
rdf:type
n3:Drug
n3:description
Perflubron emulsion (Oxygent) is being developed as an intravascular oxygen carrier designed to augment oxygen delivery in surgical patients.
n3:generalReferences
# Gale SC, Gorman GD, Copeland JG, McDonagh PF: Perflubron emulsion prevents PMN activation and improves myocardial functional recovery after cold ischemia and reperfusion. J Surg Res. 2007 Mar;138(1):135-40. Epub 2006 Dec 14. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/17173933 # Rosen NA, Hopf HW, Hunt TK: Perflubron emulsion increases subcutaneous tissue oxygen tension in rats. Wound Repair Regen. 2006 Jan-Feb;14(1):55-60. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/16476072
n3:group
investigational
n3:indication
Investigated for use/treatment in cardiac surgery, hemorrhage, and ileus.
owl:sameAs
n12:DB05791
dcterms:title
Perflubron emulsion
adms:identifier
n6:DB05791 n7:9873 n8:9489 n9:Oxygent
n3:mechanismOfAction
Perflubron emulsion (Oxygent) maintains hemodynamic stability during major surgery, thereby potentially reducing or avoiding intraoperative transfusions of donor blood in major surgery.Perflubron emulsion has ability to enable patients to be physiologically stable and safe at lower intraoperative Hb levels.
n3:IUPAC-Name
n4:271B4691-363D-11E5-9242-09173F13E4C5
n3:InChI
n4:271B4697-363D-11E5-9242-09173F13E4C5
n3:Molecular-Formula
n4:271B4696-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n4:271B4693-363D-11E5-9242-09173F13E4C5
n3:Monoisotopic-Weight
n4:271B4694-363D-11E5-9242-09173F13E4C5
n3:SMILES
n4:271B4695-363D-11E5-9242-09173F13E4C5
n3:Water-Solubility
n4:271B468F-363D-11E5-9242-09173F13E4C5
n3:logP
n4:271B4690-363D-11E5-9242-09173F13E4C5 n4:271B468D-363D-11E5-9242-09173F13E4C5
n3:logS
n4:271B468E-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Acceptor-Count
n4:271B469D-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Donor-Count
n4:271B469E-363D-11E5-9242-09173F13E4C5
n3:InChIKey
n4:271B4698-363D-11E5-9242-09173F13E4C5
n3:Polar-Surface-Area--PSA-
n4:271B4699-363D-11E5-9242-09173F13E4C5
n3:Polarizability
n4:271B469B-363D-11E5-9242-09173F13E4C5
n3:Refractivity
n4:271B469A-363D-11E5-9242-09173F13E4C5
n3:Rotatable-Bond-Count
n4:271B469C-363D-11E5-9242-09173F13E4C5
n3:Bioavailability
n4:271B46A1-363D-11E5-9242-09173F13E4C5
n3:Ghose-Filter
n4:271B46A3-363D-11E5-9242-09173F13E4C5
n3:MDDR-Like-Rule
n4:271B46A4-363D-11E5-9242-09173F13E4C5
n3:Number-of-Rings
n4:271B46A0-363D-11E5-9242-09173F13E4C5
n3:Physiological-Charge
n4:271B469F-363D-11E5-9242-09173F13E4C5
n3:Rule-of-Five
n4:271B46A2-363D-11E5-9242-09173F13E4C5
n3:Traditional-IUPAC-Name
n4:271B4692-363D-11E5-9242-09173F13E4C5