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Namespace Prefixes

PrefixIRI
n2http://linked.opendata.cz/resource/drugbank/drug/
dctermshttp://purl.org/dc/terms/
n13http://linked.opendata.cz/resource/drugbank/drug/DB04936/identifier/chemspider/
n12http://linked.opendata.cz/resource/drugbank/drug/DB04936/identifier/chebi/
n9http://linked.opendata.cz/resource/drugbank/drug/DB04936/identifier/wikipedia/
n6http://bio2rdf.org/drugbank:
admshttp://www.w3.org/ns/adms#
n11http://linked.opendata.cz/resource/drugbank/drug/DB04936/identifier/pubchem-compound/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
owlhttp://www.w3.org/2002/07/owl#
n8http://linked.opendata.cz/resource/drugbank/drug/DB04936/identifier/pubchem-substance/
n3http://linked.opendata.cz/ontology/drugbank/
n4http://linked.opendata.cz/resource/drugbank/property/
n10http://linked.opendata.cz/resource/drugbank/drug/DB04936/identifier/drugbank/
xsdhhttp://www.w3.org/2001/XMLSchema#

Statements

Subject Item
n2:DB04936
rdf:type
n3:Drug
n3:description
Tagatose is a functional sweetener. It is a naturally occurring monosaccharide, specifically a hexose. It is often found in dairy products, and is very similar in texture to sucrose (table sugar) and is 92% as sweet, but with only 38% of the calories. It is approved as a food additive as a low calorie sweetener. Additionally, it is under investigation by Spherix for the treatment of obesity and type II diabetes.
n3:generalReferences
# Donner TW, Wilber JF, Ostrowski D: D-tagatose, a novel hexose: acute effects on carbohydrate tolerance in subjects with and without type 2 diabetes. Diabetes Obes Metab. 1999 Sep;1(5):285-91. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/11225640
n3:group
investigational
n3:indication
Intended for use as a therapeutic adjunct in the treatment of type II diabetes.
owl:sameAs
n6:DB04936
dcterms:title
Tagatose
adms:identifier
n8:10225176 n9:Tagatose n10:DB04936 n11:92092 n12:33954 n13:83142
n3:mechanismOfAction
he steps in the metabolism of tagatose are identical to those for fructose or fruit sugar but tagatose is incompletely absorbed. Only 15-20 percent of tagatose is absorbed in the small intestine. The major part of ingested tagatose is fermented in the colon by indigenous microflora, resulting in the production of short-chain fatty acids. The short chain fatty acids are absorbed almost completely and metabolized.
n3:synonym
lyxo-2-hexulose D-lyxo-hex-2-ulose D-tag D-Tagatose DL-tagatose
n3:IUPAC-Name
n4:271B5FFC-363D-11E5-9242-09173F13E4C5
n3:InChI
n4:271B6002-363D-11E5-9242-09173F13E4C5
n3:Molecular-Formula
n4:271B6001-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n4:271B5FFE-363D-11E5-9242-09173F13E4C5
n3:Monoisotopic-Weight
n4:271B5FFF-363D-11E5-9242-09173F13E4C5
n3:SMILES
n4:271B6000-363D-11E5-9242-09173F13E4C5
n3:Water-Solubility
n4:271B5FFA-363D-11E5-9242-09173F13E4C5
n3:logP
n4:271B5FF8-363D-11E5-9242-09173F13E4C5 n4:271B5FFB-363D-11E5-9242-09173F13E4C5
n3:logS
n4:271B5FF9-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Acceptor-Count
n4:271B6008-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Donor-Count
n4:271B6009-363D-11E5-9242-09173F13E4C5
n3:InChIKey
n4:271B6003-363D-11E5-9242-09173F13E4C5
n3:Polar-Surface-Area--PSA-
n4:271B6004-363D-11E5-9242-09173F13E4C5
n3:Polarizability
n4:271B6006-363D-11E5-9242-09173F13E4C5
n3:Refractivity
n4:271B6005-363D-11E5-9242-09173F13E4C5
n3:Rotatable-Bond-Count
n4:271B6007-363D-11E5-9242-09173F13E4C5
n3:absorption
Only 15-20 percent of tagatose is absorbed in the small intestine.
n3:affectedOrganism
Humans and other mammals
n3:casRegistryNumber
17598-81-1
n3:category
n3:Bioavailability
n4:271B600E-363D-11E5-9242-09173F13E4C5
n3:Ghose-Filter
n4:271B6010-363D-11E5-9242-09173F13E4C5
n3:MDDR-Like-Rule
n4:271B6011-363D-11E5-9242-09173F13E4C5
n3:Melting-Point
n4:271B6012-363D-11E5-9242-09173F13E4C5
n3:Number-of-Rings
n4:271B600D-363D-11E5-9242-09173F13E4C5
n3:Physiological-Charge
n4:271B600C-363D-11E5-9242-09173F13E4C5
n3:Rule-of-Five
n4:271B600F-363D-11E5-9242-09173F13E4C5
n3:Traditional-IUPAC-Name
n4:271B5FFD-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-acidic-
n4:271B600A-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-basic-
n4:271B600B-363D-11E5-9242-09173F13E4C5