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Namespace Prefixes

PrefixIRI
n2http://linked.opendata.cz/resource/drugbank/drug/
dctermshttp://purl.org/dc/terms/
foafhttp://xmlns.com/foaf/0.1/
n7http://linked.opendata.cz/resource/mesh/concept/
n21http://www.drugs.com/
n12http://linked.opendata.cz/resource/drugbank/drug/DB03575/identifier/chemspider/
n17http://bio2rdf.org/drugbank:
admshttp://www.w3.org/ns/adms#
n14http://linked.opendata.cz/resource/drugbank/drug/DB03575/identifier/pharmgkb/
n11http://linked.opendata.cz/resource/drugbank/drug/DB03575/identifier/wikipedia/
n9http://wifo5-03.informatik.uni-mannheim.de/drugbank/resource/drugs/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n16http://linked.opendata.cz/resource/drugbank/drug/DB03575/identifier/kegg-compound/
n13http://linked.opendata.cz/resource/drugbank/drug/DB03575/identifier/pdb/
n6http://linked.opendata.cz/ontology/mesh/
owlhttp://www.w3.org/2002/07/owl#
n18http://linked.opendata.cz/resource/drugbank/drug/DB03575/identifier/pubchem-compound/
n3http://linked.opendata.cz/ontology/drugbank/
n4http://linked.opendata.cz/resource/drugbank/property/
xsdhhttp://www.w3.org/2001/XMLSchema#
n19http://linked.opendata.cz/resource/drugbank/drug/DB03575/identifier/pubchem-substance/
n15http://linked.opendata.cz/resource/drugbank/drug/DB03575/identifier/drugbank/

Statements

Subject Item
n2:DB03575
rdf:type
n3:Drug
n3:description
A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (receptors, N-methyl-D-aspartate). As a drug of abuse, it is known as PCP and Angel Dust. [PubChem]
n3:group
illicit
owl:sameAs
n9:DB03575 n17:DB03575
dcterms:title
Phencyclidine
adms:identifier
n11:Phencyclidine n12:6224 n13:1PC n14:PA128406980 n15:DB03575 n16:C07575 n18:6468 n19:46508889
n3:mechanismOfAction
The N-methyl-D-Aspartate (NMDA) receptor, a type of ionotropic receptor, is found on the dendrites of neurons and receives signals in the form of neurotransmitters. It is a major excitatory receptor in the brain. Normal physiological function requires that the activated receptor fluxes positive ions through the channel part of the receptor. PCP enters the ion channel from the outside of the neuron and binds, reversibly, to a site in the channel pore, blocking the flux of positive ions into the cell. PCP therefore inhibits depolarization of neurons and interferes with cognitive and other functions of the nervous system. [Wikipedia]
n3:synonym
PCP 1-(1-Phenylcyclohexyl)piperidine
n3:salt
n3:synthesisReference
"DrugSyn.org":http://www.drugsyn.org/Phencyclidine.htm
n6:hasConcept
n7:M0016495
foaf:page
n21:phencyclidine.html
n3:IUPAC-Name
n4:271B5522-363D-11E5-9242-09173F13E4C5
n3:InChI
n4:271B5528-363D-11E5-9242-09173F13E4C5
n3:Molecular-Formula
n4:271B5527-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n4:271B5524-363D-11E5-9242-09173F13E4C5
n3:Monoisotopic-Weight
n4:271B5525-363D-11E5-9242-09173F13E4C5
n3:SMILES
n4:271B5526-363D-11E5-9242-09173F13E4C5
n3:Water-Solubility
n4:271B5520-363D-11E5-9242-09173F13E4C5
n3:logP
n4:271B5539-363D-11E5-9242-09173F13E4C5 n4:271B551E-363D-11E5-9242-09173F13E4C5 n4:271B5521-363D-11E5-9242-09173F13E4C5
n3:logS
n4:271B551F-363D-11E5-9242-09173F13E4C5
n3:pKa
n4:271B553B-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Acceptor-Count
n4:271B552E-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Donor-Count
n4:271B552F-363D-11E5-9242-09173F13E4C5
n3:InChIKey
n4:271B5529-363D-11E5-9242-09173F13E4C5
n3:Polar-Surface-Area--PSA-
n4:271B552A-363D-11E5-9242-09173F13E4C5
n3:Polarizability
n4:271B552C-363D-11E5-9242-09173F13E4C5
n3:Refractivity
n4:271B552B-363D-11E5-9242-09173F13E4C5
n3:Rotatable-Bond-Count
n4:271B552D-363D-11E5-9242-09173F13E4C5
n3:affectedOrganism
Humans and other mammals
n3:caco2-Permeability
n4:271B553A-363D-11E5-9242-09173F13E4C5
n3:casRegistryNumber
77-10-1
n3:category
n3:Bioavailability
n4:271B5533-363D-11E5-9242-09173F13E4C5
n3:Boiling-Point
n4:271B5538-363D-11E5-9242-09173F13E4C5
n3:Ghose-Filter
n4:271B5535-363D-11E5-9242-09173F13E4C5
n3:MDDR-Like-Rule
n4:271B5536-363D-11E5-9242-09173F13E4C5
n3:Melting-Point
n4:271B5537-363D-11E5-9242-09173F13E4C5
n3:Number-of-Rings
n4:271B5532-363D-11E5-9242-09173F13E4C5
n3:Physiological-Charge
n4:271B5531-363D-11E5-9242-09173F13E4C5
n3:Rule-of-Five
n4:271B5534-363D-11E5-9242-09173F13E4C5
n3:Traditional-IUPAC-Name
n4:271B5523-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-basic-
n4:271B5530-363D-11E5-9242-09173F13E4C5