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Namespace Prefixes

PrefixIRI
n2http://linked.opendata.cz/resource/drugbank/drug/
dctermshttp://purl.org/dc/terms/
n9http://linked.opendata.cz/resource/drugbank/drug/DB01791/identifier/chemspider/
n17http://linked.opendata.cz/resource/mesh/concept/
n4http://linked.opendata.cz/resource/drugbank/drug/DB01791/identifier/wikipedia/
n13http://bio2rdf.org/drugbank:
n11http://linked.opendata.cz/resource/drugbank/drug/DB01791/identifier/bindingdb/
n14http://linked.opendata.cz/resource/drugbank/drug/DB01791/identifier/pdb/
admshttp://www.w3.org/ns/adms#
n15http://linked.opendata.cz/resource/drugbank/drug/DB01791/identifier/pubchem-compound/
n8http://wifo5-03.informatik.uni-mannheim.de/drugbank/resource/drugs/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n12http://linked.opendata.cz/resource/drugbank/drug/DB01791/identifier/pubchem-substance/
owlhttp://www.w3.org/2002/07/owl#
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n16http://linked.opendata.cz/ontology/mesh/
n5http://linked.opendata.cz/ontology/drugbank/
n6http://linked.opendata.cz/resource/drugbank/property/
xsdhhttp://www.w3.org/2001/XMLSchema#

Statements

Subject Item
n2:DB01791
rdf:type
n5:Drug
n5:description
Piclamilast (RP-73,401), is a selective PDE4 inhibitor. It is comparable to other PDE4 inhibitors for its anti-inflammatory effects. It has been investigated for its applications to the treatment of conditions such as chronic obstructive pulmonary disease, bronchopulmonary dysplasia and asthma. It is a second generation compound that exhibits structural functionalities of the PDE4 inhibitors cilomilast and roflumilast. The structure for piclamilast was first elucidated in a 1995 European patent application.
n5:group
experimental
owl:sameAs
n8:DB01791 n13:DB01791
dcterms:title
Piclamilast
adms:identifier
n4:Piclamilast n9:136184 n10:DB01791 n11:14775 n12:46508612 n14:PIL n15:154575
n5:synonym
RP 73-401
n16:hasConcept
n17:M0231880
n5:IUPAC-Name
n6:271B46EC-363D-11E5-9242-09173F13E4C5
n5:InChI
n6:271B46F2-363D-11E5-9242-09173F13E4C5
n5:Molecular-Formula
n6:271B46F1-363D-11E5-9242-09173F13E4C5
n5:Molecular-Weight
n6:271B46EE-363D-11E5-9242-09173F13E4C5
n5:Monoisotopic-Weight
n6:271B46EF-363D-11E5-9242-09173F13E4C5
n5:SMILES
n6:271B46F0-363D-11E5-9242-09173F13E4C5
n5:Water-Solubility
n6:271B46EA-363D-11E5-9242-09173F13E4C5
n5:logP
n6:271B46EB-363D-11E5-9242-09173F13E4C5 n6:271B46E8-363D-11E5-9242-09173F13E4C5
n5:logS
n6:271B46E9-363D-11E5-9242-09173F13E4C5
n5:H-Bond-Acceptor-Count
n6:271B46F8-363D-11E5-9242-09173F13E4C5
n5:H-Bond-Donor-Count
n6:271B46F9-363D-11E5-9242-09173F13E4C5
n5:InChIKey
n6:271B46F3-363D-11E5-9242-09173F13E4C5
n5:Polar-Surface-Area--PSA-
n6:271B46F4-363D-11E5-9242-09173F13E4C5
n5:Polarizability
n6:271B46F6-363D-11E5-9242-09173F13E4C5
n5:Refractivity
n6:271B46F5-363D-11E5-9242-09173F13E4C5
n5:Rotatable-Bond-Count
n6:271B46F7-363D-11E5-9242-09173F13E4C5
n5:affectedOrganism
Humans and other mammals
n5:casRegistryNumber
144035-83-6
n5:category
n5:Bioavailability
n6:271B46FE-363D-11E5-9242-09173F13E4C5
n5:Ghose-Filter
n6:271B4700-363D-11E5-9242-09173F13E4C5
n5:MDDR-Like-Rule
n6:271B4701-363D-11E5-9242-09173F13E4C5
n5:Number-of-Rings
n6:271B46FD-363D-11E5-9242-09173F13E4C5
n5:Physiological-Charge
n6:271B46FC-363D-11E5-9242-09173F13E4C5
n5:Rule-of-Five
n6:271B46FF-363D-11E5-9242-09173F13E4C5
n5:Traditional-IUPAC-Name
n6:271B46ED-363D-11E5-9242-09173F13E4C5
n5:pKa--strongest-acidic-
n6:271B46FA-363D-11E5-9242-09173F13E4C5
n5:pKa--strongest-basic-
n6:271B46FB-363D-11E5-9242-09173F13E4C5