This HTML5 document contains 59 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
n2http://linked.opendata.cz/resource/drugbank/drug/
dctermshttp://purl.org/dc/terms/
n6http://linked.opendata.cz/resource/drugbank/drug/DB01612/identifier/chebi/
n14http://linked.opendata.cz/resource/mesh/concept/
n17http://linked.opendata.cz/resource/drugbank/company/
foafhttp://xmlns.com/foaf/0.1/
n16http://linked.opendata.cz/resource/drugbank/drug/DB01612/identifier/pharmgkb/
n15http://linked.opendata.cz/resource/drugbank/drug/DB01612/identifier/wikipedia/
n20http://bio2rdf.org/drugbank:
n7http://linked.opendata.cz/resource/drugbank/drug/DB01612/identifier/kegg-compound/
n11http://www.drugs.com/cons/
admshttp://www.w3.org/ns/adms#
n12http://www.rxlist.com/cgi/generic/
n19http://wifo5-03.informatik.uni-mannheim.de/drugbank/resource/drugs/
n8http://linked.opendata.cz/resource/drugbank/drug/DB01612/identifier/kegg-drug/
n9http://linked.opendata.cz/resource/drugbank/drug/DB01612/identifier/drugbank/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n13http://linked.opendata.cz/ontology/mesh/
owlhttp://www.w3.org/2002/07/owl#
n3http://linked.opendata.cz/ontology/drugbank/
n4http://linked.opendata.cz/resource/drugbank/property/
xsdhhttp://www.w3.org/2001/XMLSchema#
n22http://linked.opendata.cz/resource/atc/
n21http://linked.opendata.cz/ontology/sukl/drug/

Statements

Subject Item
n2:DB01612
rdf:type
n3:Drug
n3:description
Amyl Nitrite is an antihypertensive medicine. Amyl nitrite is employed medically to treat heart diseases such as angina and to treat cyanide poisoning. Like other alkyl nitrites, amyl nitrite is bioactive in mammals, being a vasodilator which is the basis of its use as a prescription medicine. As an inhalant, it also has psychoactive effect which has led to illegal drug use.
n3:group
approved
n3:indication
For the rapid relief of angina pectoris.
owl:sameAs
n19:DB01612 n20:DB01612
dcterms:title
Amyl Nitrite
adms:identifier
n6:55344 n7:C07457 n8:D00517 n9:DB01612 n15:Amyl_nitrite n16:PA164750570
n3:mechanismOfAction
Amyl nitrite's antianginal action is thought to be the result of a reduction in systemic and pulmonary arterial pressure (afterload) and decreased cardiac output because of peripheral vasodilation, rather than coronary artery dilation. Amyl nitrite is a source of nitric acid, which accounts for the mechanism described above. As an antidote (to cyanide poisoning), amyl nitrite promotes formation of methemoglobin, which combines with cyanide to form nontoxic cyanmethemoglobin.
n3:packager
n17:271B5C29-363D-11E5-9242-09173F13E4C5 n17:271B5C2A-363D-11E5-9242-09173F13E4C5 n17:271B5C28-363D-11E5-9242-09173F13E4C5
n3:synonym
n-pentyl nitrite Nitramyl Amyl nitrosum Isoamyl nitrite 1-Nitropentane Amyl nitrite Pentyl nitrite n-Amyl nitrite
n3:toxicity
Overdose symptoms include nausea, emesis (vomiting), hypotension, hypoventilation, dyspnea (shortness of breath), and syncope (fainting)
n13:hasConcept
n14:M0001045
foaf:page
n11:amyl-nitrite-inhalation-oral-nebulization.html n12:amylnitrite.htm
n3:IUPAC-Name
n4:271B5C2F-363D-11E5-9242-09173F13E4C5
n3:InChI
n4:271B5C35-363D-11E5-9242-09173F13E4C5
n3:Molecular-Formula
n4:271B5C34-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n4:271B5C31-363D-11E5-9242-09173F13E4C5
n3:Monoisotopic-Weight
n4:271B5C32-363D-11E5-9242-09173F13E4C5
n3:SMILES
n4:271B5C33-363D-11E5-9242-09173F13E4C5
n3:Water-Solubility
n4:271B5C2D-363D-11E5-9242-09173F13E4C5
n3:logP
n4:271B5C2B-363D-11E5-9242-09173F13E4C5 n4:271B5C2E-363D-11E5-9242-09173F13E4C5
n3:logS
n4:271B5C2C-363D-11E5-9242-09173F13E4C5
n21:hasATCCode
n22:V03AB22
n3:H-Bond-Acceptor-Count
n4:271B5C3B-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Donor-Count
n4:271B5C3C-363D-11E5-9242-09173F13E4C5
n3:InChIKey
n4:271B5C36-363D-11E5-9242-09173F13E4C5
n3:Polar-Surface-Area--PSA-
n4:271B5C37-363D-11E5-9242-09173F13E4C5
n3:Polarizability
n4:271B5C39-363D-11E5-9242-09173F13E4C5
n3:Refractivity
n4:271B5C38-363D-11E5-9242-09173F13E4C5
n3:Rotatable-Bond-Count
n4:271B5C3A-363D-11E5-9242-09173F13E4C5
n3:absorption
Amyl nitrite vapors are absorbed rapidly through the pulmonary alveoli, manifesting therapeutic effects within one minute after inhalation.
n3:affectedOrganism
Humans and other mammals
n3:casRegistryNumber
110-46-3
n3:category
n3:Bioavailability
n4:271B5C40-363D-11E5-9242-09173F13E4C5
n3:Ghose-Filter
n4:271B5C42-363D-11E5-9242-09173F13E4C5
n3:MDDR-Like-Rule
n4:271B5C43-363D-11E5-9242-09173F13E4C5
n3:Number-of-Rings
n4:271B5C3F-363D-11E5-9242-09173F13E4C5
n3:Physiological-Charge
n4:271B5C3E-363D-11E5-9242-09173F13E4C5
n3:Rule-of-Five
n4:271B5C41-363D-11E5-9242-09173F13E4C5
n3:Traditional-IUPAC-Name
n4:271B5C30-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-basic-
n4:271B5C3D-363D-11E5-9242-09173F13E4C5