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Namespace Prefixes

PrefixIRI
n2http://linked.opendata.cz/resource/drugbank/drug/
dctermshttp://purl.org/dc/terms/
n14http://linked.opendata.cz/resource/drugbank/drug/DB01563/identifier/wikipedia/
n21http://linked.opendata.cz/resource/AHFS/
n6http://linked.opendata.cz/resource/drugbank/drug/DB01563/identifier/pharmgkb/
foafhttp://xmlns.com/foaf/0.1/
n15http://linked.opendata.cz/resource/drugbank/company/
n10http://linked.opendata.cz/resource/drugbank/drug/DB01563/identifier/kegg-compound/
n9http://linked.opendata.cz/resource/drugbank/drug/DB01563/identifier/pubchem-compound/
n13http://bio2rdf.org/drugbank:
n25http://linked.opendata.cz/resource/drugbank/drug/DB01563/identifier/pubchem-substance/
n11http://linked.opendata.cz/resource/drugbank/drug/DB01563/identifier/kegg-drug/
n12http://linked.opendata.cz/resource/drugbank/drug/DB01563/identifier/drugbank/
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n23http://linked.opendata.cz/resource/drugbank/medicinal-product/
owlhttp://www.w3.org/2002/07/owl#
n3http://linked.opendata.cz/ontology/drugbank/
n18http://www.drugs.com/cdi/
n4http://linked.opendata.cz/resource/drugbank/property/
n22http://linked.opendata.cz/resource/drugbank/drug/DB01563/identifier/chemspider/
xsdhhttp://www.w3.org/2001/XMLSchema#
n19http://linked.opendata.cz/resource/drugbank/drug/DB01563/identifier/chebi/
n20http://linked.opendata.cz/ontology/sukl/drug/

Statements

Subject Item
n2:DB01563
rdf:type
n3:Drug
n3:description
A hypnotic and sedative used in the treatment of insomnia. The safety margin is too narrow for chloral hydrate to be used as a general anesthetic in humans, but it is commonly used for that purpose in animal experiments. It is no longer considered useful as an anti-anxiety medication. [PubChem]
n3:group
illicit experimental
n3:indication
Mainly used as a hyponotic in the treatment of insomnia; however, it is only effective as a hypnotic for short-term use. May be used as a routine sedative preoperatively to decrease anxiety and cause sedation and/or sleep with respiration depression or cough reflex.
owl:sameAs
n8:DB01563 n13:DB01563
dcterms:title
Chloral hydrate
adms:identifier
n6:PA448925 n9:2707 n10:C06899 n11:D01302 n12:DB01563 n14:Chloral_hydrate n19:28142 n22:2606 n25:46507155
n3:packager
n15:271B55E1-363D-11E5-9242-09173F13E4C5 n15:271B55E2-363D-11E5-9242-09173F13E4C5 n15:271B55DF-363D-11E5-9242-09173F13E4C5 n15:271B55E0-363D-11E5-9242-09173F13E4C5 n15:271B55E5-363D-11E5-9242-09173F13E4C5 n15:271B55E6-363D-11E5-9242-09173F13E4C5 n15:271B55E3-363D-11E5-9242-09173F13E4C5 n15:271B55E4-363D-11E5-9242-09173F13E4C5 n15:271B55D9-363D-11E5-9242-09173F13E4C5 n15:271B55DA-363D-11E5-9242-09173F13E4C5 n15:271B55D8-363D-11E5-9242-09173F13E4C5 n15:271B55DD-363D-11E5-9242-09173F13E4C5 n15:271B55DE-363D-11E5-9242-09173F13E4C5 n15:271B55DB-363D-11E5-9242-09173F13E4C5 n15:271B55DC-363D-11E5-9242-09173F13E4C5
n3:routeOfElimination
Trichloroethanol, trichloroethanol glucuronide, and trichloroacetic acid are excreted in the urine. Some trichloroethanol glucuronide may be secreted into bile and excreted in the feces.
n20:hasAHFSCode
n21:28-24-92
foaf:page
n17:chloralhyd.htm n18:chloral-hydrate.html
n3:IUPAC-Name
n4:271B55EC-363D-11E5-9242-09173F13E4C5
n3:InChI
n4:271B55F2-363D-11E5-9242-09173F13E4C5
n3:Molecular-Formula
n4:271B55F1-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n4:271B55EE-363D-11E5-9242-09173F13E4C5
n3:Monoisotopic-Weight
n4:271B55EF-363D-11E5-9242-09173F13E4C5
n3:SMILES
n4:271B55F0-363D-11E5-9242-09173F13E4C5
n3:Water-Solubility
n4:271B5602-363D-11E5-9242-09173F13E4C5 n4:271B55EA-363D-11E5-9242-09173F13E4C5
n3:logP
n4:271B5605-363D-11E5-9242-09173F13E4C5 n4:271B55E8-363D-11E5-9242-09173F13E4C5 n4:271B55EB-363D-11E5-9242-09173F13E4C5
n3:logS
n4:271B55E9-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Acceptor-Count
n4:271B55F8-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Donor-Count
n4:271B55F9-363D-11E5-9242-09173F13E4C5
n3:InChIKey
n4:271B55F3-363D-11E5-9242-09173F13E4C5
n3:Polar-Surface-Area--PSA-
n4:271B55F4-363D-11E5-9242-09173F13E4C5
n3:Polarizability
n4:271B55F6-363D-11E5-9242-09173F13E4C5
n3:Refractivity
n4:271B55F5-363D-11E5-9242-09173F13E4C5
n3:Rotatable-Bond-Count
n4:271B55F7-363D-11E5-9242-09173F13E4C5
n3:absorption
Rapidly absorbed in the GI tract following oral or rectal administration. Chloral hydrate and its active metabolite, trichloroethanol, have been detected in CSF, umbilical cord blood, fetal blood, and amniotic fluid.
n3:casRegistryNumber
302-17-0
n3:containedIn
n23:271B55E7-363D-11E5-9242-09173F13E4C5
n3:Bioavailability
n4:271B55FE-363D-11E5-9242-09173F13E4C5
n3:Boiling-Point
n4:271B5604-363D-11E5-9242-09173F13E4C5
n3:Ghose-Filter
n4:271B5600-363D-11E5-9242-09173F13E4C5
n3:MDDR-Like-Rule
n4:271B5601-363D-11E5-9242-09173F13E4C5
n3:Melting-Point
n4:271B5603-363D-11E5-9242-09173F13E4C5
n3:Number-of-Rings
n4:271B55FD-363D-11E5-9242-09173F13E4C5
n3:Physiological-Charge
n4:271B55FC-363D-11E5-9242-09173F13E4C5
n3:Rule-of-Five
n4:271B55FF-363D-11E5-9242-09173F13E4C5
n3:Traditional-IUPAC-Name
n4:271B55ED-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-acidic-
n4:271B55FA-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-basic-
n4:271B55FB-363D-11E5-9242-09173F13E4C5