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Namespace Prefixes

PrefixIRI
n2http://linked.opendata.cz/resource/drugbank/drug/
dctermshttp://purl.org/dc/terms/
n13http://linked.opendata.cz/resource/drugbank/drug/DB01486/identifier/drugbank/
n15http://linked.opendata.cz/resource/mesh/concept/
n17http://bio2rdf.org/drugbank:
n12http://linked.opendata.cz/resource/drugbank/drug/DB01486/identifier/chemspider/
admshttp://www.w3.org/ns/adms#
n6http://wifo5-03.informatik.uni-mannheim.de/drugbank/resource/drugs/
n4http://linked.opendata.cz/resource/drugbank/drug/DB01486/identifier/wikipedia/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n7http://linked.opendata.cz/ontology/drugbank/
n14http://linked.opendata.cz/ontology/mesh/
owlhttp://www.w3.org/2002/07/owl#
n10http://linked.opendata.cz/resource/drugbank/drug/DB01486/identifier/kegg-compound/
n8http://linked.opendata.cz/resource/drugbank/property/
xsdhhttp://www.w3.org/2001/XMLSchema#
n11http://linked.opendata.cz/resource/drugbank/drug/DB01486/identifier/pubchem-compound/
n9http://linked.opendata.cz/resource/drugbank/drug/DB01486/identifier/pubchem-substance/

Statements

Subject Item
n2:DB01486
rdf:type
n7:Drug
n7:description
Cathine (β-hydroxyamphetamine) is a monoamine alkaloid found in the shrub Catha edulis (khat). Cathine is a Schedule III drug under the Convention on Psychotropic Substances. In the United States, it is classified as a Schedule IV controlled substance. [Wikipedia]
n7:generalReferences
# Toennes SW, Harder S, Schramm M, Niess C, Kauert GF: Pharmacokinetics of cathinone, cathine and norephedrine after the chewing of khat leaves. Br J Clin Pharmacol. 2003 Jul;56(1):125-30. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/12848785
n7:group
experimental illicit
n7:halfLife
5.2 +/- 3.4 hours
n7:indication
Used to decrease appetite.
owl:sameAs
n6:DB01486 n17:DB01486
dcterms:title
Cathine
adms:identifier
n4:Cathine n9:46509110 n10:C08300 n11:441457 n12:390189 n13:DB01486
n7:synonym
D-norephedrine β-hydroxyamphetamine D-Cathine D-phenylpropanolamine Katine Pseudonorephedrine (+)-Norpseudoephedrine (1S,2R)-(+)-Norephedrine (+)-norephedrin norpseudoephedrine
n7:synthesisReference
Shawn R. Hitchcock, Jonathan Andrew Groeper, "Method of preparing pseudonorephedrine." U.S. Patent US07465830, issued December 16, 2008.
n14:hasConcept
n15:M0046817
n7:IUPAC-Name
n8:271B4F09-363D-11E5-9242-09173F13E4C5
n7:InChI
n8:271B4F0F-363D-11E5-9242-09173F13E4C5
n7:Molecular-Formula
n8:271B4F0E-363D-11E5-9242-09173F13E4C5
n7:Molecular-Weight
n8:271B4F0B-363D-11E5-9242-09173F13E4C5
n7:Monoisotopic-Weight
n8:271B4F0C-363D-11E5-9242-09173F13E4C5
n7:SMILES
n8:271B4F0D-363D-11E5-9242-09173F13E4C5
n7:Water-Solubility
n8:271B4F07-363D-11E5-9242-09173F13E4C5 n8:271B4F1F-363D-11E5-9242-09173F13E4C5
n7:logP
n8:271B4F05-363D-11E5-9242-09173F13E4C5 n8:271B4F08-363D-11E5-9242-09173F13E4C5 n8:271B4F21-363D-11E5-9242-09173F13E4C5
n7:logS
n8:271B4F06-363D-11E5-9242-09173F13E4C5
n7:H-Bond-Acceptor-Count
n8:271B4F15-363D-11E5-9242-09173F13E4C5
n7:H-Bond-Donor-Count
n8:271B4F16-363D-11E5-9242-09173F13E4C5
n7:InChIKey
n8:271B4F10-363D-11E5-9242-09173F13E4C5
n7:Polar-Surface-Area--PSA-
n8:271B4F11-363D-11E5-9242-09173F13E4C5
n7:Polarizability
n8:271B4F13-363D-11E5-9242-09173F13E4C5
n7:Refractivity
n8:271B4F12-363D-11E5-9242-09173F13E4C5
n7:Rotatable-Bond-Count
n8:271B4F14-363D-11E5-9242-09173F13E4C5
n7:absorption
The mucosa of the oral cavity is considered to be the first absorption segment, where the major proportion of the alkaloids is absorbed (mean +/- SD: 84 +/- 6% for cathine). [PMID: 12848785]
n7:affectedOrganism
Humans and other mammals
n7:casRegistryNumber
492-39-7
n7:category
n7:Bioavailability
n8:271B4F1B-363D-11E5-9242-09173F13E4C5
n7:Ghose-Filter
n8:271B4F1D-363D-11E5-9242-09173F13E4C5
n7:MDDR-Like-Rule
n8:271B4F1E-363D-11E5-9242-09173F13E4C5
n7:Melting-Point
n8:271B4F20-363D-11E5-9242-09173F13E4C5
n7:Number-of-Rings
n8:271B4F1A-363D-11E5-9242-09173F13E4C5
n7:Physiological-Charge
n8:271B4F19-363D-11E5-9242-09173F13E4C5
n7:Rule-of-Five
n8:271B4F1C-363D-11E5-9242-09173F13E4C5
n7:Traditional-IUPAC-Name
n8:271B4F0A-363D-11E5-9242-09173F13E4C5
n7:pKa--strongest-acidic-
n8:271B4F17-363D-11E5-9242-09173F13E4C5
n7:pKa--strongest-basic-
n8:271B4F18-363D-11E5-9242-09173F13E4C5