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Namespace Prefixes

PrefixIRI
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dctermshttp://purl.org/dc/terms/
n14http://linked.opendata.cz/resource/drugbank/drug/DB01423/identifier/pubchem-compound/
n19http://linked.opendata.cz/resource/mesh/concept/
n15http://linked.opendata.cz/resource/drugbank/drug/DB01423/identifier/pubchem-substance/
n17http://linked.opendata.cz/resource/drugbank/drug/DB01423/identifier/drugbank/
n13http://bio2rdf.org/drugbank:
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n16http://linked.opendata.cz/resource/drugbank/drug/DB01423/identifier/chemspider/
n6http://wifo5-03.informatik.uni-mannheim.de/drugbank/resource/drugs/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
owlhttp://www.w3.org/2002/07/owl#
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n4http://linked.opendata.cz/resource/drugbank/property/
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n12http://linked.opendata.cz/resource/drugbank/drug/DB01423/identifier/wikipedia/
n11http://linked.opendata.cz/resource/drugbank/drug/DB01423/identifier/pharmgkb/
n8http://linked.opendata.cz/resource/atc/
n7http://linked.opendata.cz/ontology/sukl/drug/

Statements

Subject Item
n2:DB01423
rdf:type
n3:Drug
n3:description
Strepronin is a mucolytic drug. A mucolytic agent is any agent which dissolves thick mucus usually used to help relieve respiratory difficulties. The viscosity of mucous secretions in the lungs is dependent upon the concentrations of mucoprotein as well as the presence of disulfide bonds between these macromolecules and DNA.
n3:group
approved
n3:indication
Strepronin is a mucolytic (expectorant) drug.
owl:sameAs
n6:DB01423 n13:DB01423
dcterms:title
Stepronin
adms:identifier
n11:PA164748630 n12:Stepronin n14:54120 n15:46507364 n16:48889 n17:DB01423
n3:mechanismOfAction
An expectorant increases bronchial secretions and mucolytics help loosen thick bronchial secretions. Expectorants reduce the thickness or viscosity of bronchial secretions thus increasing mucus flow that can be removed more easily through coughing, Mucolytics break down the chemical structure of mucus molecules. The mucus becomes thinner and can be removed more easily through coughing.
n3:synonym
Stepronine Stepronino Tiofacic Stepronin Steproninum
n18:hasConcept
n19:M0108093
n3:IUPAC-Name
n4:271B4919-363D-11E5-9242-09173F13E4C5
n3:InChI
n4:271B491F-363D-11E5-9242-09173F13E4C5
n3:Molecular-Formula
n4:271B491E-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n4:271B491B-363D-11E5-9242-09173F13E4C5
n3:Monoisotopic-Weight
n4:271B491C-363D-11E5-9242-09173F13E4C5
n3:SMILES
n4:271B491D-363D-11E5-9242-09173F13E4C5
n3:Water-Solubility
n4:271B4917-363D-11E5-9242-09173F13E4C5
n3:logP
n4:271B4915-363D-11E5-9242-09173F13E4C5 n4:271B4918-363D-11E5-9242-09173F13E4C5
n3:logS
n4:271B4916-363D-11E5-9242-09173F13E4C5
n7:hasATCCode
n8:R05CB11
n3:H-Bond-Acceptor-Count
n4:271B4925-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Donor-Count
n4:271B4926-363D-11E5-9242-09173F13E4C5
n3:InChIKey
n4:271B4920-363D-11E5-9242-09173F13E4C5
n3:Polar-Surface-Area--PSA-
n4:271B4921-363D-11E5-9242-09173F13E4C5
n3:Polarizability
n4:271B4923-363D-11E5-9242-09173F13E4C5
n3:Refractivity
n4:271B4922-363D-11E5-9242-09173F13E4C5
n3:Rotatable-Bond-Count
n4:271B4924-363D-11E5-9242-09173F13E4C5
n3:affectedOrganism
Humans and other mammals
n3:casRegistryNumber
72324-18-6
n3:category
n3:Bioavailability
n4:271B492B-363D-11E5-9242-09173F13E4C5
n3:Ghose-Filter
n4:271B492D-363D-11E5-9242-09173F13E4C5
n3:MDDR-Like-Rule
n4:271B492E-363D-11E5-9242-09173F13E4C5
n3:Number-of-Rings
n4:271B492A-363D-11E5-9242-09173F13E4C5
n3:Physiological-Charge
n4:271B4929-363D-11E5-9242-09173F13E4C5
n3:Rule-of-Five
n4:271B492C-363D-11E5-9242-09173F13E4C5
n3:Traditional-IUPAC-Name
n4:271B491A-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-acidic-
n4:271B4927-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-basic-
n4:271B4928-363D-11E5-9242-09173F13E4C5