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Namespace Prefixes

PrefixIRI
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dctermshttp://purl.org/dc/terms/
n11http://linked.opendata.cz/resource/mesh/concept/
n12http://linked.opendata.cz/resource/drugbank/drug/DB01422/identifier/chemspider/
n6http://bio2rdf.org/drugbank:
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n9http://linked.opendata.cz/resource/drugbank/drug/DB01422/identifier/wikipedia/
n19http://wifo5-03.informatik.uni-mannheim.de/drugbank/resource/drugs/
n8http://linked.opendata.cz/resource/drugbank/drug/DB01422/identifier/pharmgkb/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
owlhttp://www.w3.org/2002/07/owl#
n10http://linked.opendata.cz/ontology/mesh/
n3http://linked.opendata.cz/ontology/drugbank/
n17http://linked.opendata.cz/resource/drugbank/drug/DB01422/identifier/pubchem-compound/
n4http://linked.opendata.cz/resource/drugbank/property/
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n13http://linked.opendata.cz/resource/drugbank/drug/DB01422/identifier/pubchem-substance/
n15http://linked.opendata.cz/ontology/sukl/drug/
n16http://linked.opendata.cz/resource/atc/
n14http://linked.opendata.cz/resource/drugbank/drug/DB01422/identifier/drugbank/

Statements

Subject Item
n2:DB01422
rdf:type
n3:Drug
n3:description
Nitroxoline is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in urinary tract infections. It is a fluorquinolone that is active against bacterial gyrases.
n3:group
approved
n3:indication
Nitroxoline is an antibiotic agent.
owl:sameAs
n6:DB01422 n19:DB01422
dcterms:title
Nitroxoline
adms:identifier
n8:PA164754993 n9:Nitroxoline n12:18756 n13:46505497 n14:DB01422 n17:19910
n3:mechanismOfAction
This drug may also have antitumor activity by inhibition of type 2 methionine aminopeptidase (MetAP2) protein which is involved in angiogenesis. Its antibacterial activity may stem from the metal ion complexation vital for bacterial growth.
n3:synonym
5NOK 5-Nitrox 5-Nitro-8-oxyquinoline 5-NOK 8-Hydroxy-5-nitroquinoline 5-Nitro-8-quinolinol Nitroxolinum 5-Nitro-8-hydroxyquinoline Nitroxolina
n10:hasConcept
n11:M0046773
n3:IUPAC-Name
n4:271B48FD-363D-11E5-9242-09173F13E4C5
n3:InChI
n4:271B4903-363D-11E5-9242-09173F13E4C5
n3:Molecular-Formula
n4:271B4902-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n4:271B48FF-363D-11E5-9242-09173F13E4C5
n3:Monoisotopic-Weight
n4:271B4900-363D-11E5-9242-09173F13E4C5
n3:SMILES
n4:271B4901-363D-11E5-9242-09173F13E4C5
n3:Water-Solubility
n4:271B48FB-363D-11E5-9242-09173F13E4C5
n3:logP
n4:271B4914-363D-11E5-9242-09173F13E4C5 n4:271B48F9-363D-11E5-9242-09173F13E4C5 n4:271B48FC-363D-11E5-9242-09173F13E4C5
n3:logS
n4:271B48FA-363D-11E5-9242-09173F13E4C5
n15:hasATCCode
n16:J01XX07
n3:H-Bond-Acceptor-Count
n4:271B4909-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Donor-Count
n4:271B490A-363D-11E5-9242-09173F13E4C5
n3:InChIKey
n4:271B4904-363D-11E5-9242-09173F13E4C5
n3:Polar-Surface-Area--PSA-
n4:271B4905-363D-11E5-9242-09173F13E4C5
n3:Polarizability
n4:271B4907-363D-11E5-9242-09173F13E4C5
n3:Refractivity
n4:271B4906-363D-11E5-9242-09173F13E4C5
n3:Rotatable-Bond-Count
n4:271B4908-363D-11E5-9242-09173F13E4C5
n3:casRegistryNumber
4008-48-4
n3:category
n3:Bioavailability
n4:271B490F-363D-11E5-9242-09173F13E4C5
n3:Ghose-Filter
n4:271B4911-363D-11E5-9242-09173F13E4C5
n3:MDDR-Like-Rule
n4:271B4912-363D-11E5-9242-09173F13E4C5
n3:Melting-Point
n4:271B4913-363D-11E5-9242-09173F13E4C5
n3:Number-of-Rings
n4:271B490E-363D-11E5-9242-09173F13E4C5
n3:Physiological-Charge
n4:271B490D-363D-11E5-9242-09173F13E4C5
n3:Rule-of-Five
n4:271B4910-363D-11E5-9242-09173F13E4C5
n3:Traditional-IUPAC-Name
n4:271B48FE-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-acidic-
n4:271B490B-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-basic-
n4:271B490C-363D-11E5-9242-09173F13E4C5