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Namespace Prefixes

PrefixIRI
n2http://linked.opendata.cz/resource/drugbank/drug/
dctermshttp://purl.org/dc/terms/
foafhttp://xmlns.com/foaf/0.1/
n6http://linked.opendata.cz/resource/mesh/concept/
n21http://linked.opendata.cz/resource/drugbank/drug/DB01361/identifier/chemspider/
n12http://bio2rdf.org/drugbank:
n14http://linked.opendata.cz/resource/drugbank/drug/DB01361/identifier/wikipedia/
admshttp://www.w3.org/ns/adms#
n22http://linked.opendata.cz/resource/drugbank/drug/DB01361/identifier/pharmgkb/
n18http://www.drugs.com/mtm/
n8http://www.rxlist.com/cgi/generic/
n25http://linked.opendata.cz/resource/drugbank/drug/DB01361/identifier/pdb/
n20http://linked.opendata.cz/resource/drugbank/drug/DB01361/identifier/kegg-compound/
n11http://wifo5-03.informatik.uni-mannheim.de/drugbank/resource/drugs/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n23http://linked.opendata.cz/resource/drugbank/drug/DB01361/identifier/pubchem-compound/
n5http://linked.opendata.cz/ontology/mesh/
owlhttp://www.w3.org/2002/07/owl#
n3http://linked.opendata.cz/ontology/drugbank/
n15http://linked.opendata.cz/resource/drugbank/drug/DB01361/identifier/pubchem-substance/
n4http://linked.opendata.cz/resource/drugbank/property/
n24http://linked.opendata.cz/resource/drugbank/drug/DB01361/identifier/kegg-drug/
xsdhhttp://www.w3.org/2001/XMLSchema#
n19http://linked.opendata.cz/resource/drugbank/drug/DB01361/identifier/drugbank/
n17http://linked.opendata.cz/resource/atc/
n16http://linked.opendata.cz/ontology/sukl/drug/

Statements

Subject Item
n2:DB01361
rdf:type
n3:Drug
n3:description
A macrolide antibiotic that is similar to erythromycin.
n3:group
approved
n3:indication
For the treatment of Pneumococcal pneumonia due to susceptible strains and group A beta-hemolytic streptococcal infections of the upper respiratory tract.
owl:sameAs
n11:DB01361 n12:DB01361
dcterms:title
Troleandomycin
adms:identifier
n14:Troleandomycin n15:46508062 n19:DB01361 n20:C12753 n21:16707 n22:PA127840611 n23:202225 n24:D01322 n25:TAO
n3:mechanismOfAction
Troleandomycin acts by penetrating the bacterial cell membrane and reversibly binding to the 50 S subunit of bacterial ribosomes or near the "P" or donor site so that binding of tRNA (transfer RNA) to the donor site is blocked. Translocation of peptides from the "A" or acceptor site to the "P" or donor site is prevented, and subsequent protein synthesis is inhibited.
n3:synonym
Triacetyloleandomycin Troleandomycin TAO
n3:toxicity
Symptoms of overdose include diarrhea, nausea, stomach cramps, and vomiting.
n5:hasConcept
n6:M0021890
foaf:page
n8:troleandomycin.htm n18:troleandomycin.html
n3:IUPAC-Name
n4:271B424B-363D-11E5-9242-09173F13E4C5
n3:InChI
n4:271B4251-363D-11E5-9242-09173F13E4C5
n3:Molecular-Formula
n4:271B4250-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n4:271B424D-363D-11E5-9242-09173F13E4C5
n3:Monoisotopic-Weight
n4:271B424E-363D-11E5-9242-09173F13E4C5
n3:SMILES
n4:271B424F-363D-11E5-9242-09173F13E4C5
n3:Water-Solubility
n4:271B4249-363D-11E5-9242-09173F13E4C5
n3:logP
n4:271B424A-363D-11E5-9242-09173F13E4C5 n4:271B4247-363D-11E5-9242-09173F13E4C5
n3:logS
n4:271B4248-363D-11E5-9242-09173F13E4C5
n16:hasATCCode
n17:J01FA08
n3:H-Bond-Acceptor-Count
n4:271B4257-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Donor-Count
n4:271B4258-363D-11E5-9242-09173F13E4C5
n3:InChIKey
n4:271B4252-363D-11E5-9242-09173F13E4C5
n3:Polar-Surface-Area--PSA-
n4:271B4253-363D-11E5-9242-09173F13E4C5
n3:Polarizability
n4:271B4255-363D-11E5-9242-09173F13E4C5
n3:Refractivity
n4:271B4254-363D-11E5-9242-09173F13E4C5
n3:Rotatable-Bond-Count
n4:271B4256-363D-11E5-9242-09173F13E4C5
n3:affectedOrganism
Enteric bacteria and other eubacteria
n3:casRegistryNumber
2751-09-9
n3:category
n3:Bioavailability
n4:271B425D-363D-11E5-9242-09173F13E4C5
n3:Ghose-Filter
n4:271B425F-363D-11E5-9242-09173F13E4C5
n3:MDDR-Like-Rule
n4:271B4260-363D-11E5-9242-09173F13E4C5
n3:Number-of-Rings
n4:271B425C-363D-11E5-9242-09173F13E4C5
n3:Physiological-Charge
n4:271B425B-363D-11E5-9242-09173F13E4C5
n3:Rule-of-Five
n4:271B425E-363D-11E5-9242-09173F13E4C5
n3:Traditional-IUPAC-Name
n4:271B424C-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-acidic-
n4:271B4259-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-basic-
n4:271B425A-363D-11E5-9242-09173F13E4C5