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Namespace Prefixes

PrefixIRI
n2http://linked.opendata.cz/resource/drugbank/drug/
dctermshttp://purl.org/dc/terms/
n19http://linked.opendata.cz/resource/mesh/concept/
n6http://linked.opendata.cz/resource/drugbank/drug/DB00817/identifier/pharmgkb/
n9http://linked.opendata.cz/resource/drugbank/drug/DB00817/identifier/pubchem-compound/
n16http://bio2rdf.org/drugbank:
n7http://linked.opendata.cz/resource/drugbank/drug/DB00817/identifier/pubchem-substance/
n8http://linked.opendata.cz/resource/drugbank/drug/DB00817/identifier/kegg-drug/
admshttp://www.w3.org/ns/adms#
n11http://linked.opendata.cz/resource/drugbank/drug/DB00817/identifier/drugbank/
n17http://wifo5-03.informatik.uni-mannheim.de/drugbank/resource/drugs/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
owlhttp://www.w3.org/2002/07/owl#
n18http://linked.opendata.cz/ontology/mesh/
n3http://linked.opendata.cz/ontology/drugbank/
n4http://linked.opendata.cz/resource/drugbank/property/
n10http://linked.opendata.cz/resource/drugbank/drug/DB00817/identifier/chemspider/
xsdhhttp://www.w3.org/2001/XMLSchema#
n13http://linked.opendata.cz/resource/atc/
n12http://linked.opendata.cz/ontology/sukl/drug/

Statements

Subject Item
n2:DB00817
rdf:type
n3:Drug
n3:description
Rosoxacin is a quinolone derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. Rosoxacin is known to be effective against penicillin resistant strains and is a single dose orally administered drug, which avoids all complications of parenteral administration seen with penicillin, especially anaphylactic shock.
n3:group
approved
n3:indication
For the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients.
owl:sameAs
n16:DB00817 n17:DB00817
dcterms:title
Rosoxacin
adms:identifier
n6:PA164776843 n7:46508469 n8:D02305 n9:287180 n10:253208 n11:DB00817
n3:mechanismOfAction
Rosoxacin binds to and inhibits the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DNA replication, transcription, repair, and recombination.
n3:synonym
ROS Acrosoxacin Rosoxacin Rosoxacine Rosoxacino Roxadyl Rosoxacinum
n18:hasConcept
n19:M0075544
n3:IUPAC-Name
n4:271B433D-363D-11E5-9242-09173F13E4C5
n3:InChI
n4:271B4343-363D-11E5-9242-09173F13E4C5
n3:Molecular-Formula
n4:271B4342-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n4:271B433F-363D-11E5-9242-09173F13E4C5
n3:Monoisotopic-Weight
n4:271B4340-363D-11E5-9242-09173F13E4C5
n3:SMILES
n4:271B4341-363D-11E5-9242-09173F13E4C5
n3:Water-Solubility
n4:271B433B-363D-11E5-9242-09173F13E4C5 n4:271B4353-363D-11E5-9242-09173F13E4C5
n3:logP
n4:271B4339-363D-11E5-9242-09173F13E4C5 n4:271B433C-363D-11E5-9242-09173F13E4C5 n4:271B4355-363D-11E5-9242-09173F13E4C5
n3:logS
n4:271B433A-363D-11E5-9242-09173F13E4C5
n12:hasATCCode
n13:J01MB01
n3:H-Bond-Acceptor-Count
n4:271B4349-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Donor-Count
n4:271B434A-363D-11E5-9242-09173F13E4C5
n3:InChIKey
n4:271B4344-363D-11E5-9242-09173F13E4C5
n3:Polar-Surface-Area--PSA-
n4:271B4345-363D-11E5-9242-09173F13E4C5
n3:Polarizability
n4:271B4347-363D-11E5-9242-09173F13E4C5
n3:Refractivity
n4:271B4346-363D-11E5-9242-09173F13E4C5
n3:Rotatable-Bond-Count
n4:271B4348-363D-11E5-9242-09173F13E4C5
n3:affectedOrganism
Enteric bacteria and other eubacteria
n3:casRegistryNumber
40034-42-2
n3:category
n3:Bioavailability
n4:271B434F-363D-11E5-9242-09173F13E4C5
n3:Ghose-Filter
n4:271B4351-363D-11E5-9242-09173F13E4C5
n3:MDDR-Like-Rule
n4:271B4352-363D-11E5-9242-09173F13E4C5
n3:Melting-Point
n4:271B4354-363D-11E5-9242-09173F13E4C5
n3:Number-of-Rings
n4:271B434E-363D-11E5-9242-09173F13E4C5
n3:Physiological-Charge
n4:271B434D-363D-11E5-9242-09173F13E4C5
n3:Rule-of-Five
n4:271B4350-363D-11E5-9242-09173F13E4C5
n3:Traditional-IUPAC-Name
n4:271B433E-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-acidic-
n4:271B434B-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-basic-
n4:271B434C-363D-11E5-9242-09173F13E4C5