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Namespace Prefixes

PrefixIRI
n10http://linked.opendata.cz/resource/drugbank/drug/DB00664/identifier/pubchem-substance/
n12http://linked.opendata.cz/resource/drugbank/drug/DB00664/identifier/kegg-drug/
n2http://linked.opendata.cz/resource/drugbank/drug/
dctermshttp://purl.org/dc/terms/
n14http://linked.opendata.cz/resource/drugbank/drug/DB00664/identifier/drugbank/
n5http://linked.opendata.cz/resource/drugbank/mixture/
n17http://bio2rdf.org/drugbank:
n13http://linked.opendata.cz/resource/drugbank/drug/DB00664/identifier/chemspider/
admshttp://www.w3.org/ns/adms#
n7http://wifo5-03.informatik.uni-mannheim.de/drugbank/resource/drugs/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n19http://linked.opendata.cz/resource/drugbank/drug/DB00664/identifier/pharmgkb/
owlhttp://www.w3.org/2002/07/owl#
n3http://linked.opendata.cz/ontology/drugbank/
n4http://linked.opendata.cz/resource/drugbank/property/
n11http://linked.opendata.cz/resource/drugbank/drug/DB00664/identifier/kegg-compound/
n9http://linked.opendata.cz/resource/drugbank/drug/DB00664/identifier/pubchem-compound/
xsdhhttp://www.w3.org/2001/XMLSchema#
n16http://linked.opendata.cz/resource/atc/
n15http://linked.opendata.cz/ontology/sukl/drug/

Statements

Subject Item
n2:DB00664
rdf:type
n3:Drug
n3:description
Long-acting plasma-bound sulfonamide used for respiratory and urinary tract infections and also for malaria. [PubChem]
n3:group
withdrawn approved
n3:indication
For the treatment of urinary tract infection and chronic bronchitis.
owl:sameAs
n7:DB00664 n17:DB00664
dcterms:title
Sulfametopyrazine
adms:identifier
n9:9047 n10:46505111 n11:C12616 n12:D01216 n13:8695 n14:DB00664 n19:PA164747038
n3:mechanismOfAction
Sulfametopyrazine is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase. Para-aminobenzoic acid (PABA), a substrate of the enzyme is prevented from binding. The inhibited reaction is necessary in these organisms for the synthesis of folic acid.
n3:synonym
Kelfizina Sulfaleno Sulfalene Solfametopirazina Sulfalenum
n3:mixture
n5:271B3E79-363D-11E5-9242-09173F13E4C5 n5:271B3E78-363D-11E5-9242-09173F13E4C5
n3:IUPAC-Name
n4:271B3E7E-363D-11E5-9242-09173F13E4C5
n3:InChI
n4:271B3E84-363D-11E5-9242-09173F13E4C5
n3:Molecular-Formula
n4:271B3E83-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n4:271B3E80-363D-11E5-9242-09173F13E4C5
n3:Monoisotopic-Weight
n4:271B3E81-363D-11E5-9242-09173F13E4C5
n3:SMILES
n4:271B3E82-363D-11E5-9242-09173F13E4C5
n3:Water-Solubility
n4:271B3E7C-363D-11E5-9242-09173F13E4C5 n4:271B3E94-363D-11E5-9242-09173F13E4C5
n3:logP
n4:271B3E7A-363D-11E5-9242-09173F13E4C5 n4:271B3E7D-363D-11E5-9242-09173F13E4C5 n4:271B3E96-363D-11E5-9242-09173F13E4C5
n3:logS
n4:271B3E7B-363D-11E5-9242-09173F13E4C5
n15:hasATCCode
n16:J01ED02
n3:H-Bond-Acceptor-Count
n4:271B3E8A-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Donor-Count
n4:271B3E8B-363D-11E5-9242-09173F13E4C5
n3:InChIKey
n4:271B3E85-363D-11E5-9242-09173F13E4C5
n3:Polar-Surface-Area--PSA-
n4:271B3E86-363D-11E5-9242-09173F13E4C5
n3:Polarizability
n4:271B3E88-363D-11E5-9242-09173F13E4C5
n3:Refractivity
n4:271B3E87-363D-11E5-9242-09173F13E4C5
n3:Rotatable-Bond-Count
n4:271B3E89-363D-11E5-9242-09173F13E4C5
n3:affectedOrganism
Gram negative, positive bacteria and plasmodium
n3:casRegistryNumber
152-47-6
n3:category
n3:Bioavailability
n4:271B3E90-363D-11E5-9242-09173F13E4C5
n3:Ghose-Filter
n4:271B3E92-363D-11E5-9242-09173F13E4C5
n3:MDDR-Like-Rule
n4:271B3E93-363D-11E5-9242-09173F13E4C5
n3:Melting-Point
n4:271B3E95-363D-11E5-9242-09173F13E4C5
n3:Number-of-Rings
n4:271B3E8F-363D-11E5-9242-09173F13E4C5
n3:Physiological-Charge
n4:271B3E8E-363D-11E5-9242-09173F13E4C5
n3:Rule-of-Five
n4:271B3E91-363D-11E5-9242-09173F13E4C5
n3:Traditional-IUPAC-Name
n4:271B3E7F-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-acidic-
n4:271B3E8C-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-basic-
n4:271B3E8D-363D-11E5-9242-09173F13E4C5