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Namespace Prefixes

PrefixIRI
n2http://linked.opendata.cz/resource/drugbank/drug/
n30http://linked.opendata.cz/resource/drugbank/drug/DB00652/identifier/pubchem-substance/
dctermshttp://purl.org/dc/terms/
n29http://linked.opendata.cz/resource/AHFS/
n24http://linked.opendata.cz/resource/drugbank/drug/DB00652/identifier/kegg-drug/
foafhttp://xmlns.com/foaf/0.1/
n26http://linked.opendata.cz/resource/drugbank/drug/DB00652/identifier/iuphar/
n27http://linked.opendata.cz/resource/drugbank/drug/DB00652/identifier/drugbank/
n32http://linked.opendata.cz/resource/mesh/concept/
n13http://linked.opendata.cz/resource/drugbank/company/
n25http://linked.opendata.cz/resource/drugbank/drug/DB00652/identifier/guide-to-pharmacology/
n15http://linked.opendata.cz/resource/drugbank/dosage/
n14http://linked.opendata.cz/resource/drugbank/mixture/
n19http://bio2rdf.org/drugbank:
n21http://linked.opendata.cz/resource/drugbank/drug/DB00652/identifier/chemspider/
admshttp://www.w3.org/ns/adms#
n18http://www.rxlist.com/cgi/generic/
n10http://wifo5-03.informatik.uni-mannheim.de/drugbank/resource/drugs/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n4http://linked.opendata.cz/resource/drugbank/medicinal-product/
n8http://linked.opendata.cz/resource/drugbank/drug/DB00652/identifier/wikipedia/
owlhttp://www.w3.org/2002/07/owl#
n31http://linked.opendata.cz/ontology/mesh/
n3http://linked.opendata.cz/ontology/drugbank/
n28http://www.drugs.com/cdi/
n7http://linked.opendata.cz/resource/drugbank/drug/DB00652/identifier/pharmgkb/
n5http://linked.opendata.cz/resource/drugbank/property/
n23http://linked.opendata.cz/resource/drugbank/drug/DB00652/identifier/kegg-compound/
xsdhhttp://www.w3.org/2001/XMLSchema#
n20http://linked.opendata.cz/resource/drugbank/drug/DB00652/identifier/bindingdb/
n22http://linked.opendata.cz/resource/drugbank/drug/DB00652/identifier/pubchem-compound/
n12http://linked.opendata.cz/resource/atc/
n11http://linked.opendata.cz/ontology/sukl/drug/

Statements

Subject Item
n2:DB00652
rdf:type
n3:Drug
n3:description
The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
n3:dosage
n15:271B6228-363D-11E5-9242-09173F13E4C5
n3:group
approved
n3:halfLife
2 to 3 hours
n3:indication
For the relief of moderate to severe pain.
n3:manufacturer
n13:271B6223-363D-11E5-9242-09173F13E4C5 n13:271B6222-363D-11E5-9242-09173F13E4C5
owl:sameAs
n10:DB00652 n19:DB00652
dcterms:title
Pentazocine
adms:identifier
n7:PA164744326 n8:Pentazocine n20:50001028 n21:390041 n22:441278 n23:C07421 n24:D00498 n25:1606 n26:1606 n27:DB00652 n30:46506363
n3:mechanismOfAction
The preponderance of evidence suggests that pentazocine antagonizes the opioid effects by competing for the same receptor sites, especially the opioid mu receptor.
n3:packager
n13:271B6221-363D-11E5-9242-09173F13E4C5 n13:271B621B-363D-11E5-9242-09173F13E4C5 n13:271B621C-363D-11E5-9242-09173F13E4C5 n13:271B6219-363D-11E5-9242-09173F13E4C5 n13:271B621A-363D-11E5-9242-09173F13E4C5 n13:271B621F-363D-11E5-9242-09173F13E4C5 n13:271B6220-363D-11E5-9242-09173F13E4C5 n13:271B621D-363D-11E5-9242-09173F13E4C5 n13:271B621E-363D-11E5-9242-09173F13E4C5 n13:271B6213-363D-11E5-9242-09173F13E4C5 n13:271B6214-363D-11E5-9242-09173F13E4C5 n13:271B6211-363D-11E5-9242-09173F13E4C5 n13:271B6212-363D-11E5-9242-09173F13E4C5 n13:271B6217-363D-11E5-9242-09173F13E4C5 n13:271B6218-363D-11E5-9242-09173F13E4C5 n13:271B6215-363D-11E5-9242-09173F13E4C5 n13:271B6216-363D-11E5-9242-09173F13E4C5 n13:271B6210-363D-11E5-9242-09173F13E4C5
n3:synonym
Pentazocine Pentazocina Fortral Pentazocinum Pentazocin
n11:hasAHFSCode
n29:28-08-12
n3:foodInteraction
Take without regard to meals. Avoid alcohol.
n3:mixture
n14:271B620C-363D-11E5-9242-09173F13E4C5 n14:271B620F-363D-11E5-9242-09173F13E4C5 n14:271B620D-363D-11E5-9242-09173F13E4C5 n14:271B620E-363D-11E5-9242-09173F13E4C5
n3:salt
n31:hasConcept
n32:M0016179
foaf:page
n18:pentazocine.htm n28:pentazocine.html
n3:IUPAC-Name
n5:271B622D-363D-11E5-9242-09173F13E4C5
n3:InChI
n5:271B6233-363D-11E5-9242-09173F13E4C5
n3:Molecular-Formula
n5:271B6232-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n5:271B622F-363D-11E5-9242-09173F13E4C5
n3:Monoisotopic-Weight
n5:271B6230-363D-11E5-9242-09173F13E4C5
n3:SMILES
n5:271B6231-363D-11E5-9242-09173F13E4C5
n3:Water-Solubility
n5:271B622B-363D-11E5-9242-09173F13E4C5
n3:logP
n5:271B6229-363D-11E5-9242-09173F13E4C5 n5:271B622C-363D-11E5-9242-09173F13E4C5 n5:271B6244-363D-11E5-9242-09173F13E4C5
n3:logS
n5:271B622A-363D-11E5-9242-09173F13E4C5
n3:pKa
n5:271B6245-363D-11E5-9242-09173F13E4C5
n11:hasATCCode
n12:N02AD01
n3:H-Bond-Acceptor-Count
n5:271B6239-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Donor-Count
n5:271B623A-363D-11E5-9242-09173F13E4C5
n3:InChIKey
n5:271B6234-363D-11E5-9242-09173F13E4C5
n3:Polar-Surface-Area--PSA-
n5:271B6235-363D-11E5-9242-09173F13E4C5
n3:Polarizability
n5:271B6237-363D-11E5-9242-09173F13E4C5
n3:Refractivity
n5:271B6236-363D-11E5-9242-09173F13E4C5
n3:Rotatable-Bond-Count
n5:271B6238-363D-11E5-9242-09173F13E4C5
n3:absorption
Well absorbed from the gastro-intestinal tract.
n3:affectedOrganism
Humans and other mammals
n3:casRegistryNumber
359-83-1
n3:category
n3:containedIn
n4:271B6226-363D-11E5-9242-09173F13E4C5 n4:271B6227-363D-11E5-9242-09173F13E4C5 n4:271B6224-363D-11E5-9242-09173F13E4C5 n4:271B6225-363D-11E5-9242-09173F13E4C5
n3:Bioavailability
n5:271B623F-363D-11E5-9242-09173F13E4C5
n3:Ghose-Filter
n5:271B6241-363D-11E5-9242-09173F13E4C5
n3:MDDR-Like-Rule
n5:271B6242-363D-11E5-9242-09173F13E4C5
n3:Melting-Point
n5:271B6243-363D-11E5-9242-09173F13E4C5
n3:Number-of-Rings
n5:271B623E-363D-11E5-9242-09173F13E4C5
n3:Physiological-Charge
n5:271B623D-363D-11E5-9242-09173F13E4C5
n3:Rule-of-Five
n5:271B6240-363D-11E5-9242-09173F13E4C5
n3:Traditional-IUPAC-Name
n5:271B622E-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-acidic-
n5:271B623B-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-basic-
n5:271B623C-363D-11E5-9242-09173F13E4C5