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Namespace Prefixes

PrefixIRI
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n2http://linked.opendata.cz/resource/drugbank/drug/
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n20http://linked.opendata.cz/resource/drugbank/mixture/
n22http://bio2rdf.org/drugbank:
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n4http://linked.opendata.cz/resource/drugbank/medicinal-product/
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n3http://linked.opendata.cz/ontology/drugbank/
n25http://linked.opendata.cz/resource/drugbank/drug/DB00646/identifier/pharmgkb/
n14http://www.drugs.com/cdi/
n13http://www.rxlist.com/cgi/generic2/
n12http://linked.opendata.cz/resource/drugbank/property/
n29http://linked.opendata.cz/resource/drugbank/drug/DB00646/identifier/kegg-compound/
n10http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/
xsdhhttp://www.w3.org/2001/XMLSchema#
n26http://linked.opendata.cz/resource/drugbank/drug/DB00646/identifier/pubchem-compound/
n7http://linked.opendata.cz/resource/atc/
n6http://linked.opendata.cz/ontology/sukl/drug/

Statements

Subject Item
n2:DB00646
rdf:type
n3:Drug
n3:description
Nystatin is a polyene antifungal drug to which many molds and yeasts are sensitive, including Candida spp. Nystatin has some toxicity associated with it when given intravenously, but it is not absorbed across intact skin or mucous membranes. It is considered a relatively safe drug for treating oral or gastrointestinal fungal infections.
n3:dosage
n8:271B605D-363D-11E5-9242-09173F13E4C5 n8:271B605E-363D-11E5-9242-09173F13E4C5 n8:271B605F-363D-11E5-9242-09173F13E4C5 n8:271B6060-363D-11E5-9242-09173F13E4C5 n8:271B6050-363D-11E5-9242-09173F13E4C5 n8:271B6051-363D-11E5-9242-09173F13E4C5 n8:271B6052-363D-11E5-9242-09173F13E4C5 n8:271B6053-363D-11E5-9242-09173F13E4C5 n8:271B6054-363D-11E5-9242-09173F13E4C5 n8:271B6055-363D-11E5-9242-09173F13E4C5 n8:271B6056-363D-11E5-9242-09173F13E4C5 n8:271B6057-363D-11E5-9242-09173F13E4C5 n8:271B6058-363D-11E5-9242-09173F13E4C5 n8:271B6059-363D-11E5-9242-09173F13E4C5 n8:271B605A-363D-11E5-9242-09173F13E4C5 n8:271B605B-363D-11E5-9242-09173F13E4C5 n8:271B605C-363D-11E5-9242-09173F13E4C5
n3:generalReferences
# Akaike N, Harata N: Nystatin perforated patch recording and its applications to analyses of intracellular mechanisms. Jpn J Physiol. 1994;44(5):433-73. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/7534361
n3:group
approved
n3:indication
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
n3:manufacturer
n5:271B6017-363D-11E5-9242-09173F13E4C5 n5:271B6018-363D-11E5-9242-09173F13E4C5 n5:271B6015-363D-11E5-9242-09173F13E4C5 n5:271B6016-363D-11E5-9242-09173F13E4C5 n5:271B6014-363D-11E5-9242-09173F13E4C5 n5:271B6022-363D-11E5-9242-09173F13E4C5 n5:271B6023-363D-11E5-9242-09173F13E4C5 n5:271B6020-363D-11E5-9242-09173F13E4C5 n5:271B6021-363D-11E5-9242-09173F13E4C5 n5:271B601E-363D-11E5-9242-09173F13E4C5 n5:271B601F-363D-11E5-9242-09173F13E4C5 n5:271B6019-363D-11E5-9242-09173F13E4C5 n5:271B601D-363D-11E5-9242-09173F13E4C5 n5:271B602A-363D-11E5-9242-09173F13E4C5 n5:271B602B-363D-11E5-9242-09173F13E4C5 n5:271B6028-363D-11E5-9242-09173F13E4C5 n5:271B6029-363D-11E5-9242-09173F13E4C5 n5:271B601C-363D-11E5-9242-09173F13E4C5 n5:271B6026-363D-11E5-9242-09173F13E4C5 n5:271B6027-363D-11E5-9242-09173F13E4C5 n5:271B601A-363D-11E5-9242-09173F13E4C5 n5:271B6024-363D-11E5-9242-09173F13E4C5 n5:271B601B-363D-11E5-9242-09173F13E4C5 n5:271B6025-363D-11E5-9242-09173F13E4C5 n5:271B6012-363D-11E5-9242-09173F13E4C5 n5:271B6013-363D-11E5-9242-09173F13E4C5 n5:271B6010-363D-11E5-9242-09173F13E4C5 n5:271B6011-363D-11E5-9242-09173F13E4C5 n5:271B600E-363D-11E5-9242-09173F13E4C5 n5:271B600F-363D-11E5-9242-09173F13E4C5 n5:271B600C-363D-11E5-9242-09173F13E4C5 n5:271B600D-363D-11E5-9242-09173F13E4C5 n5:271B6032-363D-11E5-9242-09173F13E4C5 n5:271B6033-363D-11E5-9242-09173F13E4C5 n5:271B6030-363D-11E5-9242-09173F13E4C5 n5:271B6031-363D-11E5-9242-09173F13E4C5 n5:271B602E-363D-11E5-9242-09173F13E4C5 n5:271B602F-363D-11E5-9242-09173F13E4C5 n5:271B602C-363D-11E5-9242-09173F13E4C5 n5:271B602D-363D-11E5-9242-09173F13E4C5
owl:sameAs
n17:DB00646 n22:DB00646
dcterms:title
Nystatin
adms:identifier
n19:Nystatin n21:10128183 n23:DB00646 n24:46504780 n25:PA450666 n26:11953884 n27:D00202 n28:0574-2008-15 n29:C06572
n3:mechanismOfAction
Nystatin exerts its antifungal activity by binding to ergosterol found in fungal cell membranes. Binding to ergosterol causes the formation of pores in the membrane. Potassium and other cellular constituents leak from the pores causing cell death.
n3:packager
n5:271B5FE7-363D-11E5-9242-09173F13E4C5 n5:271B5FE8-363D-11E5-9242-09173F13E4C5 n5:271B5FE5-363D-11E5-9242-09173F13E4C5 n5:271B5FE6-363D-11E5-9242-09173F13E4C5 n5:271B5FEB-363D-11E5-9242-09173F13E4C5 n5:271B5FF6-363D-11E5-9242-09173F13E4C5 n5:271B5FE9-363D-11E5-9242-09173F13E4C5 n5:271B5FEA-363D-11E5-9242-09173F13E4C5 n5:271B5FD7-363D-11E5-9242-09173F13E4C5 n5:271B5FD8-363D-11E5-9242-09173F13E4C5 n5:271B5FD6-363D-11E5-9242-09173F13E4C5 n5:271B5FEE-363D-11E5-9242-09173F13E4C5 n5:271B5FEF-363D-11E5-9242-09173F13E4C5 n5:271B5FEC-363D-11E5-9242-09173F13E4C5 n5:271B5FED-363D-11E5-9242-09173F13E4C5 n5:271B6006-363D-11E5-9242-09173F13E4C5 n5:271B6007-363D-11E5-9242-09173F13E4C5 n5:271B6004-363D-11E5-9242-09173F13E4C5 n5:271B6005-363D-11E5-9242-09173F13E4C5 n5:271B600A-363D-11E5-9242-09173F13E4C5 n5:271B600B-363D-11E5-9242-09173F13E4C5 n5:271B6008-363D-11E5-9242-09173F13E4C5 n5:271B6009-363D-11E5-9242-09173F13E4C5 n5:271B5FFE-363D-11E5-9242-09173F13E4C5 n5:271B5FFF-363D-11E5-9242-09173F13E4C5 n5:271B5FFC-363D-11E5-9242-09173F13E4C5 n5:271B5FFD-363D-11E5-9242-09173F13E4C5 n5:271B6002-363D-11E5-9242-09173F13E4C5 n5:271B6003-363D-11E5-9242-09173F13E4C5 n5:271B6000-363D-11E5-9242-09173F13E4C5 n5:271B6001-363D-11E5-9242-09173F13E4C5 n5:271B5FF2-363D-11E5-9242-09173F13E4C5 n5:271B5FF3-363D-11E5-9242-09173F13E4C5 n5:271B5FF0-363D-11E5-9242-09173F13E4C5 n5:271B5FF1-363D-11E5-9242-09173F13E4C5 n5:271B5FFA-363D-11E5-9242-09173F13E4C5 n5:271B5FFB-363D-11E5-9242-09173F13E4C5 n5:271B5FF4-363D-11E5-9242-09173F13E4C5 n5:271B5FF5-363D-11E5-9242-09173F13E4C5 n5:271B5FDF-363D-11E5-9242-09173F13E4C5 n5:271B5FE0-363D-11E5-9242-09173F13E4C5 n5:271B5FDD-363D-11E5-9242-09173F13E4C5 n5:271B5FDE-363D-11E5-9242-09173F13E4C5 n5:271B5FE3-363D-11E5-9242-09173F13E4C5 n5:271B5FE4-363D-11E5-9242-09173F13E4C5 n5:271B5FE1-363D-11E5-9242-09173F13E4C5 n5:271B5FE2-363D-11E5-9242-09173F13E4C5 n5:271B5FDB-363D-11E5-9242-09173F13E4C5 n5:271B5FDC-363D-11E5-9242-09173F13E4C5 n5:271B5FD9-363D-11E5-9242-09173F13E4C5 n5:271B5FDA-363D-11E5-9242-09173F13E4C5 n5:271B5FF9-363D-11E5-9242-09173F13E4C5 n5:271B5FF7-363D-11E5-9242-09173F13E4C5 n5:271B5FF8-363D-11E5-9242-09173F13E4C5
n3:synonym
Nystatin Nystatine Mycostatin NYS Nistatina Nystatinum
n6:hasAHFSCode
n11:08-14-28 n11:84-04-08-28
n3:foodInteraction
Take without regard to meals.
n3:mixture
n20:271B5FD4-363D-11E5-9242-09173F13E4C5 n20:271B5FD5-363D-11E5-9242-09173F13E4C5 n20:271B5FD2-363D-11E5-9242-09173F13E4C5 n20:271B5FD3-363D-11E5-9242-09173F13E4C5 n20:271B5FD0-363D-11E5-9242-09173F13E4C5 n20:271B5FD1-363D-11E5-9242-09173F13E4C5 n20:271B5FCE-363D-11E5-9242-09173F13E4C5 n20:271B5FCF-363D-11E5-9242-09173F13E4C5 n20:271B5FCC-363D-11E5-9242-09173F13E4C5 n20:271B5FCD-363D-11E5-9242-09173F13E4C5 n20:271B5FCA-363D-11E5-9242-09173F13E4C5 n20:271B5FCB-363D-11E5-9242-09173F13E4C5 n20:271B5FC9-363D-11E5-9242-09173F13E4C5
n3:salt
foaf:page
n10:myc1279.shtml n13:nystat.htm n14:nystatin.html
n3:IUPAC-Name
n12:271B6065-363D-11E5-9242-09173F13E4C5
n3:InChI
n12:271B606B-363D-11E5-9242-09173F13E4C5
n3:Molecular-Formula
n12:271B606A-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n12:271B6067-363D-11E5-9242-09173F13E4C5
n3:Monoisotopic-Weight
n12:271B6068-363D-11E5-9242-09173F13E4C5
n3:SMILES
n12:271B6069-363D-11E5-9242-09173F13E4C5
n3:Water-Solubility
n12:271B607B-363D-11E5-9242-09173F13E4C5 n12:271B6063-363D-11E5-9242-09173F13E4C5
n3:logP
n12:271B607D-363D-11E5-9242-09173F13E4C5 n12:271B6061-363D-11E5-9242-09173F13E4C5 n12:271B6064-363D-11E5-9242-09173F13E4C5
n3:logS
n12:271B6062-363D-11E5-9242-09173F13E4C5
n6:hasATCCode
n7:G01AA01 n7:D01AA01 n7:A07AA02
n3:H-Bond-Acceptor-Count
n12:271B6071-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Donor-Count
n12:271B6072-363D-11E5-9242-09173F13E4C5
n3:InChIKey
n12:271B606C-363D-11E5-9242-09173F13E4C5
n3:Polar-Surface-Area--PSA-
n12:271B606D-363D-11E5-9242-09173F13E4C5
n3:Polarizability
n12:271B606F-363D-11E5-9242-09173F13E4C5
n3:Refractivity
n12:271B606E-363D-11E5-9242-09173F13E4C5
n3:Rotatable-Bond-Count
n12:271B6070-363D-11E5-9242-09173F13E4C5
n3:absorption
Nystatin is not absorbed from intact skin or mucous membrane.
n3:affectedOrganism
Fungi
n3:casRegistryNumber
1400-61-9
n3:category
n3:containedIn
n4:271B6047-363D-11E5-9242-09173F13E4C5 n4:271B6048-363D-11E5-9242-09173F13E4C5 n4:271B6045-363D-11E5-9242-09173F13E4C5 n4:271B6046-363D-11E5-9242-09173F13E4C5 n4:271B604B-363D-11E5-9242-09173F13E4C5 n4:271B604C-363D-11E5-9242-09173F13E4C5 n4:271B6049-363D-11E5-9242-09173F13E4C5 n4:271B604A-363D-11E5-9242-09173F13E4C5 n4:271B603F-363D-11E5-9242-09173F13E4C5 n4:271B6040-363D-11E5-9242-09173F13E4C5 n4:271B603D-363D-11E5-9242-09173F13E4C5 n4:271B603E-363D-11E5-9242-09173F13E4C5 n4:271B6043-363D-11E5-9242-09173F13E4C5 n4:271B6044-363D-11E5-9242-09173F13E4C5 n4:271B6041-363D-11E5-9242-09173F13E4C5 n4:271B6042-363D-11E5-9242-09173F13E4C5 n4:271B6037-363D-11E5-9242-09173F13E4C5 n4:271B6038-363D-11E5-9242-09173F13E4C5 n4:271B6035-363D-11E5-9242-09173F13E4C5 n4:271B6036-363D-11E5-9242-09173F13E4C5 n4:271B603B-363D-11E5-9242-09173F13E4C5 n4:271B603C-363D-11E5-9242-09173F13E4C5 n4:271B6039-363D-11E5-9242-09173F13E4C5 n4:271B603A-363D-11E5-9242-09173F13E4C5 n4:271B6034-363D-11E5-9242-09173F13E4C5 n4:271B604F-363D-11E5-9242-09173F13E4C5 n4:271B604D-363D-11E5-9242-09173F13E4C5 n4:271B604E-363D-11E5-9242-09173F13E4C5
n3:Bioavailability
n12:271B6077-363D-11E5-9242-09173F13E4C5
n3:Ghose-Filter
n12:271B6079-363D-11E5-9242-09173F13E4C5
n3:MDDR-Like-Rule
n12:271B607A-363D-11E5-9242-09173F13E4C5
n3:Melting-Point
n12:271B607C-363D-11E5-9242-09173F13E4C5
n3:Number-of-Rings
n12:271B6076-363D-11E5-9242-09173F13E4C5
n3:Physiological-Charge
n12:271B6075-363D-11E5-9242-09173F13E4C5
n3:Rule-of-Five
n12:271B6078-363D-11E5-9242-09173F13E4C5
n3:Traditional-IUPAC-Name
n12:271B6066-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-acidic-
n12:271B6073-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-basic-
n12:271B6074-363D-11E5-9242-09173F13E4C5