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Namespace Prefixes

PrefixIRI
n2http://linked.opendata.cz/resource/drugbank/drug/
dctermshttp://purl.org/dc/terms/
n7http://linked.opendata.cz/resource/mesh/concept/
n5http://linked.opendata.cz/resource/drugbank/company/
n17http://bio2rdf.org/drugbank:
admshttp://www.w3.org/ns/adms#
n16http://linked.opendata.cz/resource/drugbank/drug/DB00306/identifier/wikipedia/
n14http://linked.opendata.cz/resource/drugbank/drug/DB00306/identifier/pharmgkb/
n9http://wifo5-03.informatik.uni-mannheim.de/drugbank/resource/drugs/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n6http://linked.opendata.cz/ontology/mesh/
owlhttp://www.w3.org/2002/07/owl#
n3http://linked.opendata.cz/ontology/drugbank/
n4http://linked.opendata.cz/resource/drugbank/property/
n13http://linked.opendata.cz/resource/drugbank/drug/DB00306/identifier/kegg-drug/
xsdhhttp://www.w3.org/2001/XMLSchema#
n18http://linked.opendata.cz/resource/drugbank/drug/DB00306/identifier/drugbank/
n11http://linked.opendata.cz/resource/atc/
n10http://linked.opendata.cz/ontology/sukl/drug/

Statements

Subject Item
n2:DB00306
rdf:type
n3:Drug
n3:description
Talbutal, also called 5-allyl-5-sec-butylbarbituric acid, is a barbiturate with a short to intermediate duration of action. Talbutal is a schedule III drug in the U.S.
n3:group
approved illicit
n3:indication
For use as a sedative and hypnotic.
n3:manufacturer
n5:271B4F1A-363D-11E5-9242-09173F13E4C5
owl:sameAs
n9:DB00306 n17:DB00306
dcterms:title
Talbutal
adms:identifier
n13:D06887 n14:PA164779051 n16:Talbutal n18:DB00306
n3:mechanismOfAction
Talbutal binds at a distinct binding site associated with a Cl<sup>-</sup> ionopore at the GABA<sub>A</sub> receptor, increasing the duration of time for which the Cl<sup>-</sup> ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged.
n3:synonym
Lotusate Talbutale sec-Butyl allyl barbituric acid 5-allyl-5-sec-butylbarbituric acid Talbutalum (RS)-5-allyl-5-sec-butylpyrimidine-2,4,6(1H,3H,5H)-trione
n3:toxicity
Symptoms of acute barbiturate poisoning include drowsiness, confusion, coma, respiratory depression, hypotension, and shock.
n6:hasConcept
n7:M0413630
n3:IUPAC-Name
n4:271B4F1F-363D-11E5-9242-09173F13E4C5
n3:InChI
n4:271B4F25-363D-11E5-9242-09173F13E4C5
n3:Molecular-Formula
n4:271B4F24-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n4:271B4F21-363D-11E5-9242-09173F13E4C5
n3:Monoisotopic-Weight
n4:271B4F22-363D-11E5-9242-09173F13E4C5
n3:SMILES
n4:271B4F23-363D-11E5-9242-09173F13E4C5
n3:Water-Solubility
n4:271B4F34-363D-11E5-9242-09173F13E4C5 n4:271B4F1D-363D-11E5-9242-09173F13E4C5
n3:logP
n4:271B4F36-363D-11E5-9242-09173F13E4C5 n4:271B4F1E-363D-11E5-9242-09173F13E4C5 n4:271B4F1B-363D-11E5-9242-09173F13E4C5
n3:logS
n4:271B4F1C-363D-11E5-9242-09173F13E4C5
n3:pKa
n4:271B4F37-363D-11E5-9242-09173F13E4C5
n10:hasATCCode
n11:N05CA07
n3:H-Bond-Acceptor-Count
n4:271B4F2B-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Donor-Count
n4:271B4F2C-363D-11E5-9242-09173F13E4C5
n3:InChIKey
n4:271B4F26-363D-11E5-9242-09173F13E4C5
n3:Polar-Surface-Area--PSA-
n4:271B4F27-363D-11E5-9242-09173F13E4C5
n3:Polarizability
n4:271B4F29-363D-11E5-9242-09173F13E4C5
n3:Refractivity
n4:271B4F28-363D-11E5-9242-09173F13E4C5
n3:Rotatable-Bond-Count
n4:271B4F2A-363D-11E5-9242-09173F13E4C5
n3:affectedOrganism
Humans and other mammals
n3:casRegistryNumber
115-44-6
n3:Bioavailability
n4:271B4F30-363D-11E5-9242-09173F13E4C5
n3:Ghose-Filter
n4:271B4F32-363D-11E5-9242-09173F13E4C5
n3:MDDR-Like-Rule
n4:271B4F33-363D-11E5-9242-09173F13E4C5
n3:Melting-Point
n4:271B4F35-363D-11E5-9242-09173F13E4C5
n3:Number-of-Rings
n4:271B4F2F-363D-11E5-9242-09173F13E4C5
n3:Physiological-Charge
n4:271B4F2E-363D-11E5-9242-09173F13E4C5
n3:Rule-of-Five
n4:271B4F31-363D-11E5-9242-09173F13E4C5
n3:Traditional-IUPAC-Name
n4:271B4F20-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-acidic-
n4:271B4F2D-363D-11E5-9242-09173F13E4C5