This HTML5 document contains 55 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
n2http://linked.opendata.cz/resource/drugbank/drug/
n12http://linked.opendata.cz/resource/drugbank/drug/DB00171/identifier/pharmgkb/
n13http://linked.opendata.cz/resource/drugbank/drug/DB00171/identifier/wikipedia/
dctermshttp://purl.org/dc/terms/
n9http://linked.opendata.cz/resource/drugbank/drug/DB00171/identifier/pdb/
n15http://linked.opendata.cz/resource/mesh/concept/
n11http://linked.opendata.cz/resource/drugbank/drug/DB00171/identifier/kegg-compound/
n8http://linked.opendata.cz/resource/drugbank/drug/DB00171/identifier/bindingdb/
n18http://bio2rdf.org/drugbank:
n10http://linked.opendata.cz/resource/drugbank/drug/DB00171/identifier/drugbank/
admshttp://www.w3.org/ns/adms#
n17http://wifo5-03.informatik.uni-mannheim.de/drugbank/resource/drugs/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n14http://linked.opendata.cz/ontology/mesh/
owlhttp://www.w3.org/2002/07/owl#
n3http://linked.opendata.cz/ontology/drugbank/
n4http://linked.opendata.cz/resource/drugbank/property/
n7http://linked.opendata.cz/resource/drugbank/drug/DB00171/identifier/chebi/
xsdhhttp://www.w3.org/2001/XMLSchema#

Statements

Subject Item
n2:DB00171
rdf:type
n3:Drug
n3:description
An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. [PubChem]
n3:generalReferences
# Gajewski E, Steckler DK, Goldberg RN: Thermodynamics of the hydrolysis of adenosine 5'-triphosphate to adenosine 5'-diphosphate. J Biol Chem. 1986 Sep 25;261(27):12733-7. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/3528161 # Storer AC, Cornish-Bowden A: Concentration of MgATP2- and other ions in solution. Calculation of the true concentrations of species present in mixtures of associating ions. Biochem J. 1976 Oct 1;159(1):1-5. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/11772 # Wilson JE, Chin A: Chelation of divalent cations by ATP, studied by titration calorimetry. Anal Biochem. 1991 Feb 15;193(1):16-9. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/1645933 # Garfinkel L, Altschuld RA, Garfinkel D: Magnesium in cardiac energy metabolism. J Mol Cell Cardiol. 1986 Oct;18(10):1003-13. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/3537318 # Parsons M: Glycosomes: parasites and the divergence of peroxisomal purpose. Mol Microbiol. 2004 Aug;53(3):717-24. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/15255886
n3:group
approved nutraceutical
n3:indication
For nutritional supplementation, also for treating dietary shortage or imbalance
owl:sameAs
n17:DB00171 n18:DB00171
dcterms:title
Adenosine triphosphate
adms:identifier
n7:15422 n8:2 n9:ATP n10:DB00171 n11:C00002 n12:PA164743471 n13:Adenosine_triphosphate
n3:mechanismOfAction
ATP is able to store and transport chemical energy within cells. ATP also plays an important role in the synthesis of nucleic acids. ATP can be produced by various cellular processes, most typically in mitochondria by oxidative phosphorylation under the catalytic influence of ATP synthase. The total quantity of ATP in the human body is about 0.1 mole. The energy used by human cells requires the hydrolysis of 200 to 300 moles of ATP daily. This means that each ATP molecule is recycled 2000 to 3000 times during a single day. ATP cannot be stored, hence its consumption must closely follow its synthesis.
n3:synonym
ATP Adenosine-5'-triphosphate Adenosine 5'-triphosphate
n3:toxicity
Oral LD<sub>50</sub> in rats is > 2 g/kg.
n3:synthesisReference
George M. Whitesides, Patricia E. Garrett, Merrell G. Siegel, "Method for preparing adenosine triphosphate." U.S. Patent US4164444, issued April, 1975.
n14:hasConcept
n15:M0000395
n3:IUPAC-Name
n4:271B5071-363D-11E5-9242-09173F13E4C5
n3:InChI
n4:271B5077-363D-11E5-9242-09173F13E4C5
n3:Molecular-Formula
n4:271B5076-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n4:271B5073-363D-11E5-9242-09173F13E4C5
n3:Monoisotopic-Weight
n4:271B5074-363D-11E5-9242-09173F13E4C5
n3:SMILES
n4:271B5075-363D-11E5-9242-09173F13E4C5
n3:Water-Solubility
n4:271B506F-363D-11E5-9242-09173F13E4C5 n4:271B5087-363D-11E5-9242-09173F13E4C5
n3:logP
n4:271B5070-363D-11E5-9242-09173F13E4C5 n4:271B506D-363D-11E5-9242-09173F13E4C5 n4:271B5089-363D-11E5-9242-09173F13E4C5
n3:logS
n4:271B506E-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Acceptor-Count
n4:271B507D-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Donor-Count
n4:271B507E-363D-11E5-9242-09173F13E4C5
n3:InChIKey
n4:271B5078-363D-11E5-9242-09173F13E4C5
n3:Polar-Surface-Area--PSA-
n4:271B5079-363D-11E5-9242-09173F13E4C5
n3:Polarizability
n4:271B507B-363D-11E5-9242-09173F13E4C5
n3:Refractivity
n4:271B507A-363D-11E5-9242-09173F13E4C5
n3:Rotatable-Bond-Count
n4:271B507C-363D-11E5-9242-09173F13E4C5
n3:affectedOrganism
Humans and other mammals
n3:casRegistryNumber
56-65-5
n3:category
n3:Bioavailability
n4:271B5083-363D-11E5-9242-09173F13E4C5
n3:Ghose-Filter
n4:271B5085-363D-11E5-9242-09173F13E4C5
n3:MDDR-Like-Rule
n4:271B5086-363D-11E5-9242-09173F13E4C5
n3:Melting-Point
n4:271B5088-363D-11E5-9242-09173F13E4C5
n3:Number-of-Rings
n4:271B5082-363D-11E5-9242-09173F13E4C5
n3:Physiological-Charge
n4:271B5081-363D-11E5-9242-09173F13E4C5
n3:Rule-of-Five
n4:271B5084-363D-11E5-9242-09173F13E4C5
n3:Traditional-IUPAC-Name
n4:271B5072-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-acidic-
n4:271B507F-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-basic-
n4:271B5080-363D-11E5-9242-09173F13E4C5