This HTML5 document contains 88 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
n2http://linked.opendata.cz/resource/drugbank/drug/
dctermshttp://purl.org/dc/terms/
n24http://linked.opendata.cz/resource/AHFS/
n15http://linked.opendata.cz/resource/mesh/concept/
n20http://linked.opendata.cz/resource/drugbank/drug/DB00139/identifier/chemspider/
n4http://linked.opendata.cz/resource/drugbank/company/
n19http://linked.opendata.cz/resource/drugbank/drug/DB00139/identifier/chebi/
n6http://linked.opendata.cz/resource/drugbank/mixture/
n21http://linked.opendata.cz/resource/drugbank/drug/DB00139/identifier/pharmgkb/
n22http://linked.opendata.cz/resource/drugbank/drug/DB00139/identifier/wikipedia/
n8http://bio2rdf.org/drugbank:
admshttp://www.w3.org/ns/adms#
n16http://linked.opendata.cz/resource/drugbank/drug/DB00139/identifier/bindingdb/
n18http://linked.opendata.cz/resource/drugbank/drug/DB00139/identifier/kegg-compound/
n12http://linked.opendata.cz/resource/drugbank/drug/DB00139/identifier/pdb/
n13http://linked.opendata.cz/resource/drugbank/drug/DB00139/identifier/pubchem-compound/
n11http://wifo5-03.informatik.uni-mannheim.de/drugbank/resource/drugs/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n26http://linked.opendata.cz/resource/drugbank/medicinal-product/
owlhttp://www.w3.org/2002/07/owl#
n10http://linked.opendata.cz/resource/drugbank/drug/DB00139/identifier/pubchem-substance/
n14http://linked.opendata.cz/ontology/mesh/
n3http://linked.opendata.cz/ontology/drugbank/
n17http://linked.opendata.cz/resource/drugbank/drug/DB00139/identifier/drugbank/
n5http://linked.opendata.cz/resource/drugbank/property/
xsdhhttp://www.w3.org/2001/XMLSchema#
n23http://linked.opendata.cz/ontology/sukl/drug/

Statements

Subject Item
n2:DB00139
rdf:type
n3:Drug
n3:description
A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
n3:group
approved nutraceutical
n3:indication
For nutritional supplementation, also for treating dietary shortage or imbalance
owl:sameAs
n8:DB00139 n11:DB00139
dcterms:title
Succinic acid
adms:identifier
n10:46505859 n12:SIN n13:1110 n16:26121 n17:DB00139 n18:C00042 n19:15741 n20:1078 n21:PA164747739 n22:Succinate
n3:mechanismOfAction
Succinate is an essential component of the Krebs or citric acid cycle and serves an electron donor in the production of fumaric acid and FADH2. It also has been shown to be a good "natural" antibiotic because of its relative acidic or caustic nature (high concentrations can even cause burns). Succinate supplements have been shown to help reduce the effects of hangovers by activating the degradation of acetaldehyde - a toxic byproduct of alcohol metabolism - into CO2 and H2O through aerobic metabolism. Succinic acid has been shown to stimulate neural system recovery and bolster the immune system. Claims have also been made that it boosts awareness, concentration and reflexes.
n3:packager
n4:271B4A27-363D-11E5-9242-09173F13E4C5 n4:271B4A2E-363D-11E5-9242-09173F13E4C5 n4:271B4A2F-363D-11E5-9242-09173F13E4C5 n4:271B4A2C-363D-11E5-9242-09173F13E4C5 n4:271B4A2D-363D-11E5-9242-09173F13E4C5 n4:271B4A2A-363D-11E5-9242-09173F13E4C5 n4:271B4A2B-363D-11E5-9242-09173F13E4C5 n4:271B4A28-363D-11E5-9242-09173F13E4C5 n4:271B4A29-363D-11E5-9242-09173F13E4C5 n4:271B4A30-363D-11E5-9242-09173F13E4C5 n4:271B4A31-363D-11E5-9242-09173F13E4C5
n3:synonym
Acidum succinicum Bernsteinsaeure Dihydrofumaric acid Butanedioic acid Succinic acid Ethylenesuccinic acid HOOC-CH2-CH2-COOH 1,2-Ethanedicarboxylic acid Succinate Butanedionic acid Acide succinique Butandisaeure e363 Bernsteinsaure Spirit of amber Asuccin Amber acid Acide butanedioique
n3:toxicity
Oral rat LD<sub>50</sub>: 2260 mg/kg
n23:hasAHFSCode
n24:92-02-00%2A
n3:mixture
n6:271B4A26-363D-11E5-9242-09173F13E4C5
n3:synthesisReference
Michael Diamantoglou, Gerhard Meyer, "Process for the production of water-insoluble fibers of cellulose monoesters of maleic acid, succinic acid and phthalic acid, having an extremely high absorbability for water and physiological liquids." U.S. Patent US4734239, issued April, 1941.
n14:hasConcept
n15:M0029380
n3:IUPAC-Name
n5:271B4A37-363D-11E5-9242-09173F13E4C5
n3:InChI
n5:271B4A3D-363D-11E5-9242-09173F13E4C5
n3:Molecular-Formula
n5:271B4A3C-363D-11E5-9242-09173F13E4C5
n3:Molecular-Weight
n5:271B4A39-363D-11E5-9242-09173F13E4C5
n3:Monoisotopic-Weight
n5:271B4A3A-363D-11E5-9242-09173F13E4C5
n3:SMILES
n5:271B4A3B-363D-11E5-9242-09173F13E4C5
n3:Water-Solubility
n5:271B4A35-363D-11E5-9242-09173F13E4C5 n5:271B4A4C-363D-11E5-9242-09173F13E4C5
n3:logP
n5:271B4A33-363D-11E5-9242-09173F13E4C5 n5:271B4A36-363D-11E5-9242-09173F13E4C5 n5:271B4A4F-363D-11E5-9242-09173F13E4C5
n3:logS
n5:271B4A34-363D-11E5-9242-09173F13E4C5 n5:271B4A50-363D-11E5-9242-09173F13E4C5
n3:pKa
n5:271B4A51-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Acceptor-Count
n5:271B4A43-363D-11E5-9242-09173F13E4C5
n3:H-Bond-Donor-Count
n5:271B4A44-363D-11E5-9242-09173F13E4C5
n3:InChIKey
n5:271B4A3E-363D-11E5-9242-09173F13E4C5
n3:Polar-Surface-Area--PSA-
n5:271B4A3F-363D-11E5-9242-09173F13E4C5
n3:Polarizability
n5:271B4A41-363D-11E5-9242-09173F13E4C5
n3:Refractivity
n5:271B4A40-363D-11E5-9242-09173F13E4C5
n3:Rotatable-Bond-Count
n5:271B4A42-363D-11E5-9242-09173F13E4C5
n3:affectedOrganism
Humans and other mammals
n3:casRegistryNumber
110-15-6
n3:category
n3:containedIn
n26:271B4A32-363D-11E5-9242-09173F13E4C5
n3:Bioavailability
n5:271B4A48-363D-11E5-9242-09173F13E4C5
n3:Boiling-Point
n5:271B4A4E-363D-11E5-9242-09173F13E4C5
n3:Ghose-Filter
n5:271B4A4A-363D-11E5-9242-09173F13E4C5
n3:MDDR-Like-Rule
n5:271B4A4B-363D-11E5-9242-09173F13E4C5
n3:Melting-Point
n5:271B4A4D-363D-11E5-9242-09173F13E4C5
n3:Number-of-Rings
n5:271B4A47-363D-11E5-9242-09173F13E4C5
n3:Physiological-Charge
n5:271B4A46-363D-11E5-9242-09173F13E4C5
n3:Rule-of-Five
n5:271B4A49-363D-11E5-9242-09173F13E4C5
n3:Traditional-IUPAC-Name
n5:271B4A38-363D-11E5-9242-09173F13E4C5
n3:pKa--strongest-acidic-
n5:271B4A45-363D-11E5-9242-09173F13E4C5