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Statements

Subject Item
n2:RIV%2F86652052%3A_____%2F14%3A%230000268%21RIV15-MV0-86652052
rdf:type
skos:Concept n9:Vysledek
dcterms:description
Eleven underground miners studies evaluated the risk of lung cancer from exposure in underground mines. The resulting model of the Biological Effects of Ionizing Radiation (BEIR) VI Committee considered linear exposure response relationship, which was modified by time since exposure, attained age and exposure rate. The effect of age at exposure was not explicitly evaluated. The paper aims to show that the modifying effect of age at exposure is substantial if time-since-exposure modification is simultaneously used in the model. When the excess relative risk per unit exposure (ERR/WLM) is adjusted for time since exposure, the ERR/WLM corresponding to age <15 is 0.013 and ERR/WLM in subsequent categories decreases gradually up to the age of 40+ years, which is only 0.004. In comparison with the BEIRVI model, the present model predicts higher risks at younger ages and the risk decreases more rapidly with time. Eleven underground miners studies evaluated the risk of lung cancer from exposure in underground mines. The resulting model of the Biological Effects of Ionizing Radiation (BEIR) VI Committee considered linear exposure response relationship, which was modified by time since exposure, attained age and exposure rate. The effect of age at exposure was not explicitly evaluated. The paper aims to show that the modifying effect of age at exposure is substantial if time-since-exposure modification is simultaneously used in the model. When the excess relative risk per unit exposure (ERR/WLM) is adjusted for time since exposure, the ERR/WLM corresponding to age <15 is 0.013 and ERR/WLM in subsequent categories decreases gradually up to the age of 40+ years, which is only 0.004. In comparison with the BEIRVI model, the present model predicts higher risks at younger ages and the risk decreases more rapidly with time.
dcterms:title
Effect of age at exposure in 11 underground miners studies Effect of age at exposure in 11 underground miners studies
skos:prefLabel
Effect of age at exposure in 11 underground miners studies Effect of age at exposure in 11 underground miners studies
skos:notation
RIV/86652052:_____/14:#0000268!RIV15-MV0-86652052
n4:aktivita
n6:I
n4:aktivity
I
n4:cisloPeriodika
1-3
n4:dodaniDat
n8:2015
n4:domaciTvurceVysledku
n10:8266840
n4:druhVysledku
n12:J
n4:duvernostUdaju
n16:S
n4:entitaPredkladatele
n15:predkladatel
n4:idSjednocenehoVysledku
13102
n4:idVysledku
RIV/86652052:_____/14:#0000268
n4:jazykVysledku
n13:eng
n4:klicovaSlova
lung cancer; radon; uranium miners
n4:klicoveSlovo
n5:radon n5:uranium%20miners n5:lung%20cancer
n4:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n4:kontrolniKodProRIV
[9EEBD2A4C12F]
n4:nazevZdroje
Radiation Protection Dosimetry
n4:obor
n17:DN
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
1
n4:rokUplatneniVysledku
n8:2014
n4:svazekPeriodika
160
n4:tvurceVysledku
Tomášek, Ladislav
n4:wos
000339953000031
s:issn
0144-8420
s:numberOfPages
4
n11:doi
10.1093/rpd/ncu068