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Statements

Subject Item
n2:RIV%2F86652052%3A_____%2F11%3A%230000025%21RIV12-MZ0-86652052
rdf:type
skos:Concept n11:Vysledek
rdfs:seeAlso
http://oem.bmj.com/content/68/Suppl_1/A87.2.abstract?sid=2819f88b-4901-4f59-a180-c6337eb705b7
dcterms:description
The study is based on two Czech cohorts of U miners and people exposed to high levels of radon in houses. including 1107 and 240 cases of lung cancer. Individual smoking data were collected for most of subjects (68% and 75%, respectively). The relative risk is evaluated in dependence on cumulated exposure with effect modification by time since exposure and smoking. The excess relative risk per unit exposure from earlier periods of exposure (20 years and more) is about 1/3 in comparison to recent exposures (5-19 years). Smoking specific estimates of excess relative risk per unit exposure were 3-5 times higher among never smokers in both studies. The interaction of radon and smoking is evaluated by geometric mixture models. When smoking specific doses to the lungs and modifying effect of time since exposure are used, the combined effect of radon and smoking is close to the additive model. The study is based on two Czech cohorts of U miners and people exposed to high levels of radon in houses. including 1107 and 240 cases of lung cancer. Individual smoking data were collected for most of subjects (68% and 75%, respectively). The relative risk is evaluated in dependence on cumulated exposure with effect modification by time since exposure and smoking. The excess relative risk per unit exposure from earlier periods of exposure (20 years and more) is about 1/3 in comparison to recent exposures (5-19 years). Smoking specific estimates of excess relative risk per unit exposure were 3-5 times higher among never smokers in both studies. The interaction of radon and smoking is evaluated by geometric mixture models. When smoking specific doses to the lungs and modifying effect of time since exposure are used, the combined effect of radon and smoking is close to the additive model.
dcterms:title
Lung cancer risk from occupational and environmental radon and role of smoking Lung cancer risk from occupational and environmental radon and role of smoking
skos:prefLabel
Lung cancer risk from occupational and environmental radon and role of smoking Lung cancer risk from occupational and environmental radon and role of smoking
skos:notation
RIV/86652052:_____/11:#0000025!RIV12-MZ0-86652052
n11:predkladatel
n12:ico%3A86652052
n6:aktivita
n9:P
n6:aktivity
P(NS10596)
n6:dodaniDat
n8:2012
n6:domaciTvurceVysledku
n14:8266840
n6:druhVysledku
n15:O
n6:duvernostUdaju
n16:S
n6:entitaPredkladatele
n10:predkladatel
n6:idSjednocenehoVysledku
210098
n6:idVysledku
RIV/86652052:_____/11:#0000025
n6:jazykVysledku
n13:eng
n6:klicovaSlova
lung cancer; radon; smoking
n6:klicoveSlovo
n7:radon n7:lung%20cancer n7:smoking
n6:kontrolniKodProRIV
[5E5E03EC7F08]
n6:obor
n17:DN
n6:pocetDomacichTvurcuVysledku
1
n6:pocetTvurcuVysledku
1
n6:projekt
n19:NS10596
n6:rokUplatneniVysledku
n8:2011
n6:tvurceVysledku
Tomášek, Ladislav
n5:doi
10.1136/oemed-2011-100382.285