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Statements

Subject Item
n2:RIV%2F70883521%3A28610%2F14%3A43872710%21RIV15-MSM-28610___
rdf:type
n8:Vysledek skos:Concept
dcterms:description
Silicone magnetic composite was developed for application as a heat mediator in arterial embolization hyperthermia. The material provides simultaneously the ability for secure embolization of tumor blood vessels, high heating rate in alternating magnetic fields allowed for application in magnetic hyperthermia and radiopaque property enabling the detection of its position by means of angiography. The composite represents a silicone elastomer matrix with uniformly dispersed iron oxide magnetic nanoparticles and potassium iodide micro-crystals. The silicone elastomer is formed by the reaction of silicones with vinyl- and hydro- side groups which is catalyzed by the chloroplatinic acid. The reaction has an induction period during which the composition stays liquid that makes possible to deliver it to the tumor blood vessels. After the induction period soft emboli is formed causing the occlusion of the tumor blood vessels. Material obtained guarantee rapid heating (tens of seconds) in alternating magnetic fields due to high heating ability of iron oxide magnetic nanoparticles with certain magneto-structural properties. Silicone magnetic composite was developed for application as a heat mediator in arterial embolization hyperthermia. The material provides simultaneously the ability for secure embolization of tumor blood vessels, high heating rate in alternating magnetic fields allowed for application in magnetic hyperthermia and radiopaque property enabling the detection of its position by means of angiography. The composite represents a silicone elastomer matrix with uniformly dispersed iron oxide magnetic nanoparticles and potassium iodide micro-crystals. The silicone elastomer is formed by the reaction of silicones with vinyl- and hydro- side groups which is catalyzed by the chloroplatinic acid. The reaction has an induction period during which the composition stays liquid that makes possible to deliver it to the tumor blood vessels. After the induction period soft emboli is formed causing the occlusion of the tumor blood vessels. Material obtained guarantee rapid heating (tens of seconds) in alternating magnetic fields due to high heating ability of iron oxide magnetic nanoparticles with certain magneto-structural properties.
dcterms:title
Iron Oxide Nanoparticles and Polymer Composites for Magnetic Hyperthermia Iron Oxide Nanoparticles and Polymer Composites for Magnetic Hyperthermia
skos:prefLabel
Iron Oxide Nanoparticles and Polymer Composites for Magnetic Hyperthermia Iron Oxide Nanoparticles and Polymer Composites for Magnetic Hyperthermia
skos:notation
RIV/70883521:28610/14:43872710!RIV15-MSM-28610___
n3:aktivita
n13:P
n3:aktivity
P(ED2.1.00/03.0111)
n3:dodaniDat
n10:2015
n3:domaciTvurceVysledku
n4:5059925 n4:5474353 n4:9162151
n3:druhVysledku
n12:O
n3:duvernostUdaju
n6:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
22858
n3:idVysledku
RIV/70883521:28610/14:43872710
n3:jazykVysledku
n16:eng
n3:klicovaSlova
radiopacity; rheological properties; specific loss power; iron oxide nanoparticles; embolic material; arterial embolization hyperthermia
n3:klicoveSlovo
n7:iron%20oxide%20nanoparticles n7:specific%20loss%20power n7:rheological%20properties n7:radiopacity n7:embolic%20material n7:arterial%20embolization%20hyperthermia
n3:kontrolniKodProRIV
[6D7C33D443A1]
n3:obor
n9:JI
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
4
n3:projekt
n14:ED2.1.00%2F03.0111
n3:rokUplatneniVysledku
n10:2014
n3:tvurceVysledku
Smolkova, Ilona Kazantseva, Natalia Sáha, Petr Makoveckaya, K. N.
n15:organizacniJednotka
28610