This HTML5 document contains 48 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
n9http://linked.opendata.cz/ontology/domain/vavai/riv/typAkce/
dctermshttp://purl.org/dc/terms/
n21http://localhost/temp/predkladatel/
n13http://purl.org/net/nknouf/ns/bibtex#
n16http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n8http://linked.opendata.cz/resource/domain/vavai/projekt/
n15http://linked.opendata.cz/resource/domain/vavai/subjekt/
n14http://linked.opendata.cz/ontology/domain/vavai/
n17https://schema.org/
shttp://schema.org/
n4http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F70883521%3A28610%2F13%3A43870932%21RIV14-MSM-28610___/
skoshttp://www.w3.org/2004/02/skos/core#
rdfshttp://www.w3.org/2000/01/rdf-schema#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n5http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n20http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n18http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n10http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n12http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n11http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n19http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F70883521%3A28610%2F13%3A43870932%21RIV14-MSM-28610___
rdf:type
n14:Vysledek skos:Concept
rdfs:seeAlso
http://www.nanocon.eu/files/proceedings/14/reports/2134.pdf
dcterms:description
The purpose of this study was to examine low molecular weight chitosan-grafted polylactide nanoparticles as a drug delivery system for doxorubicin and temozolomide. We investigated the effect of polylactide molecular weight on the release kinetic and encapsulation efficiency of both drugs. Polylactide (10 kDa and 60 kDa) has been linked to chitosan via coupling reaction. Chitosan-grafted-polylactide nanoparticles were prepared via ionotropic gelation method with tripolyphosphate as a linking agent. Results such as size (150-350 nm), potential (+25-35 mV), efficient encapsulation and prolonged release kinetic suggested that chitosan-grafted-poly lactic acid could be a great system for co-delivery of doxorubicin and temozolomide in Glioblastoma Multiforme treatment. The purpose of this study was to examine low molecular weight chitosan-grafted polylactide nanoparticles as a drug delivery system for doxorubicin and temozolomide. We investigated the effect of polylactide molecular weight on the release kinetic and encapsulation efficiency of both drugs. Polylactide (10 kDa and 60 kDa) has been linked to chitosan via coupling reaction. Chitosan-grafted-polylactide nanoparticles were prepared via ionotropic gelation method with tripolyphosphate as a linking agent. Results such as size (150-350 nm), potential (+25-35 mV), efficient encapsulation and prolonged release kinetic suggested that chitosan-grafted-poly lactic acid could be a great system for co-delivery of doxorubicin and temozolomide in Glioblastoma Multiforme treatment.
dcterms:title
Effect of polylactide molecular weight on doxorubicin and temozolomide release from chitosan-grafted polylactide nanoparticles Effect of polylactide molecular weight on doxorubicin and temozolomide release from chitosan-grafted polylactide nanoparticles
skos:prefLabel
Effect of polylactide molecular weight on doxorubicin and temozolomide release from chitosan-grafted polylactide nanoparticles Effect of polylactide molecular weight on doxorubicin and temozolomide release from chitosan-grafted polylactide nanoparticles
skos:notation
RIV/70883521:28610/13:43870932!RIV14-MSM-28610___
n14:predkladatel
n15:orjk%3A28610
n3:aktivita
n18:S n18:P
n3:aktivity
P(ED2.1.00/03.0111), S
n3:dodaniDat
n19:2014
n3:domaciTvurceVysledku
Di Martino, Antonio n16:6339603 n16:3382257
n3:druhVysledku
n12:D
n3:duvernostUdaju
n20:S
n3:entitaPredkladatele
n4:predkladatel
n3:idSjednocenehoVysledku
71674
n3:idVysledku
RIV/70883521:28610/13:43870932
n3:jazykVysledku
n10:eng
n3:klicovaSlova
Chitosan, Polylactide, Doxorubicin, Temozolomide, in vitro release
n3:klicoveSlovo
n5:Chitosan n5:Temozolomide n5:Doxorubicin n5:Polylactide n5:in%20vitro%20release
n3:kontrolniKodProRIV
[9A9A0479302E]
n3:mistoKonaniAkce
Brno
n3:mistoVydani
Brno
n3:nazevZdroje
Nanocon 2013
n3:obor
n11:CD
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
3
n3:projekt
n8:ED2.1.00%2F03.0111
n3:rokUplatneniVysledku
n19:2013
n3:tvurceVysledku
Di Martino, Antonio Sedlařík, Vladimír Kucharczyk, Pavel
n3:typAkce
n9:WRD
n3:zahajeniAkce
2013-10-16+02:00
s:numberOfPages
6
n13:hasPublisher
Tanger, Ltd.
n17:isbn
978-80-87294-44-4
n21:organizacniJednotka
28610