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Statements

Subject Item
n2:RIV%2F70883521%3A28610%2F10%3A63509215%21RIV11-MSM-28610___
rdf:type
n15:Vysledek skos:Concept
dcterms:description
Background: The ability of magnetic particles to be heated up by AC magnetic field has outlined a new effective method for tumour?s treatment ? magnetic hyperthermia. Recently there?ve been attempts to use the energy of electric field for the same purpose. The electro hyperthermia method works due to the significant difference in conductivity of malignant and healthy tissue which makes the method selective. Although the penetration depth of electric field is smaller than in the case of magnetic field, its absorption efficiency is higher. In order to increase the efficiency further we proposed to use electrically lossy magnetic fluid as a mediator in electro-hyperthermia. Methods: To test the effect of mediator on the heating of malignant cells, the hepatocellular carcinoma cell line (Hep G2; ATCC) and human immortalized non-tumorigenic keratinocyte cell line (HaCaT; CLS were used) were used. As the mediator, maghemite-based ferrofluid with special morphology giving rise to high dielectric losses at Background: The ability of magnetic particles to be heated up by AC magnetic field has outlined a new effective method for tumour?s treatment ? magnetic hyperthermia. Recently there?ve been attempts to use the energy of electric field for the same purpose. The electro hyperthermia method works due to the significant difference in conductivity of malignant and healthy tissue which makes the method selective. Although the penetration depth of electric field is smaller than in the case of magnetic field, its absorption efficiency is higher. In order to increase the efficiency further we proposed to use electrically lossy magnetic fluid as a mediator in electro-hyperthermia. Methods: To test the effect of mediator on the heating of malignant cells, the hepatocellular carcinoma cell line (Hep G2; ATCC) and human immortalized non-tumorigenic keratinocyte cell line (HaCaT; CLS were used) were used. As the mediator, maghemite-based ferrofluid with special morphology giving rise to high dielectric losses at
dcterms:title
In Vitro Models for Testing the Effect of Mediator on Heating in Electro-Hypertermia In Vitro Models for Testing the Effect of Mediator on Heating in Electro-Hypertermia
skos:prefLabel
In Vitro Models for Testing the Effect of Mediator on Heating in Electro-Hypertermia In Vitro Models for Testing the Effect of Mediator on Heating in Electro-Hypertermia
skos:notation
RIV/70883521:28610/10:63509215!RIV11-MSM-28610___
n3:aktivita
n16:Z
n3:aktivity
Z(MSM7088352101)
n3:dodaniDat
n12:2011
n3:domaciTvurceVysledku
n8:5628954 n8:5474353 n8:7093780 n8:3306917 Kazantseva, Natalia n8:4137132
n3:druhVysledku
n10:O
n3:duvernostUdaju
n14:S
n3:entitaPredkladatele
n4:predkladatel
n3:idSjednocenehoVysledku
263295
n3:idVysledku
RIV/70883521:28610/10:63509215
n3:jazykVysledku
n17:eng
n3:klicovaSlova
hyperthermia; in vitro; cancer
n3:klicoveSlovo
n5:hyperthermia n5:in%20vitro n5:cancer
n3:kontrolniKodProRIV
[5BF76FD7D915]
n3:obor
n11:CD
n3:pocetDomacichTvurcuVysledku
6
n3:pocetTvurcuVysledku
6
n3:rokUplatneniVysledku
n12:2010
n3:tvurceVysledku
Humpolíček, Petr Kazantseva, Natalia Sáha, Petr Moučka, Robert Valášek, Pavel Vilčáková, Jarmila
n3:zamer
n13:MSM7088352101
n9:organizacniJednotka
28610