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Statements

Subject Item
n2:RIV%2F70883521%3A28150%2F14%3A43871807%21RIV15-MSM-28150___
rdf:type
n5:Vysledek skos:Concept
dcterms:description
Introduction. Breast cancer is, now often diagnosed in patients older than 70 years due to longer life expectancy. The usual treatment is mastectomy to obviate radiotherapy or breast-conserving surgery followed by radiotherapy. The aim of this study was to investigate the need for adjuvant radiotherapy in older patients and the consequences of omitting radiotherapy following conservative surgery.Methods. An extensive database search was made of patients who had been treated for breast cancer at the Department of Oncology, University Hospital Olomouc and the Atlas Hospital in Zlin (2004-2008). We identified 738 patients of whom 190 patients (25.7%) were older than 70 years of age. These were followed up for progression-free and overall survival. The cause of death was checked for breast cancer relapse.Results. In total only 9 patients undergoing breast saving surgery were ultimately identified. No patient had confirmed local recurrence during the follow up period: Two patients have died due to distant metastasis without local relapse and one patient has died for reasons other than breast cancer.Conclusion. Omitting radiotherapy after breast saving surgery provides an opportunity for women to undergo breast saving surgery and avoid 7 weeks of radiotherapy. This could significantly improve patient quality of life. In our of many years experience and from published randomized data, this procedure is safe for a select group of patients 70 years of age and older. Introduction. Breast cancer is, now often diagnosed in patients older than 70 years due to longer life expectancy. The usual treatment is mastectomy to obviate radiotherapy or breast-conserving surgery followed by radiotherapy. The aim of this study was to investigate the need for adjuvant radiotherapy in older patients and the consequences of omitting radiotherapy following conservative surgery.Methods. An extensive database search was made of patients who had been treated for breast cancer at the Department of Oncology, University Hospital Olomouc and the Atlas Hospital in Zlin (2004-2008). We identified 738 patients of whom 190 patients (25.7%) were older than 70 years of age. These were followed up for progression-free and overall survival. The cause of death was checked for breast cancer relapse.Results. In total only 9 patients undergoing breast saving surgery were ultimately identified. No patient had confirmed local recurrence during the follow up period: Two patients have died due to distant metastasis without local relapse and one patient has died for reasons other than breast cancer.Conclusion. Omitting radiotherapy after breast saving surgery provides an opportunity for women to undergo breast saving surgery and avoid 7 weeks of radiotherapy. This could significantly improve patient quality of life. In our of many years experience and from published randomized data, this procedure is safe for a select group of patients 70 years of age and older.
dcterms:title
Omission of adjuvant radiation therapy in elderly patients with low risk breast cancer undergoing breast-conserving surgery - two center experience Omission of adjuvant radiation therapy in elderly patients with low risk breast cancer undergoing breast-conserving surgery - two center experience
skos:prefLabel
Omission of adjuvant radiation therapy in elderly patients with low risk breast cancer undergoing breast-conserving surgery - two center experience Omission of adjuvant radiation therapy in elderly patients with low risk breast cancer undergoing breast-conserving surgery - two center experience
skos:notation
RIV/70883521:28150/14:43871807!RIV15-MSM-28150___
n4:aktivita
n10:V n10:I
n4:aktivity
I, V
n4:cisloPeriodika
3
n4:dodaniDat
n8:2015
n4:domaciTvurceVysledku
n12:4522680
n4:druhVysledku
n14:J
n4:duvernostUdaju
n6:S
n4:entitaPredkladatele
n17:predkladatel
n4:idSjednocenehoVysledku
93628
n4:idVysledku
RIV/70883521:28150/14:43871807
n4:jazykVysledku
n16:eng
n4:klicovaSlova
Radiation-therapy; Elderly patients; Breast cancer
n4:klicoveSlovo
n7:Radiation-therapy n7:Elderly%20patients n7:Breast%20cancer
n4:kodStatuVydavatele
CZ - Česká republika
n4:kontrolniKodProRIV
[E1C0C8B02DF0]
n4:nazevZdroje
Biomedical Papers of the Faculty of Medicine of Palacký University in Olomouc
n4:obor
n18:FJ
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
7
n4:rokUplatneniVysledku
n8:2014
n4:svazekPeriodika
158
n4:tvurceVysledku
Vazan, Tomáš Lukešová, Lucie Gatěk, Jiří Vrána, David Švach, Ivan Pospíšková, Markéta Melichar, Bohuslav
s:issn
1213-8118
s:numberOfPages
4
n15:doi
10.5507/bp.2013.032
n11:organizacniJednotka
28150