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Statements

Subject Item
n2:RIV%2F70883521%3A28110%2F10%3A63509394%21RIV11-MSM-28110___
rdf:type
n18:Vysledek skos:Concept
dcterms:description
A rapid, simple and reliable liquid chromatographic method has been developed for the determination of thiamin, nicotinamide, panthothenic acid and pyridoxine in pharmaceutical preparations. HPLC equipped with a reversed?phase C8 was used. A mobile phase of methanol-phosphate buffer (10:90, v/v) and a flow rate of 0.8 ml.min-1 gave the most satisfactory separation of those vitamins using a UV detector set up at 204 nm and 220 nm. Detection limits ranged from 2.0 to 12.0 ?g.ml-1. When the method was applied to the determination of the vitamins, the found values were lower or close with those on the labels. The differences in the tablet contents of vitamins may be influenced by the kind of pharmaceutical preparation, by technical preparation making process and by the storage conditions. A rapid, simple and reliable liquid chromatographic method has been developed for the determination of thiamin, nicotinamide, panthothenic acid and pyridoxine in pharmaceutical preparations. HPLC equipped with a reversed?phase C8 was used. A mobile phase of methanol-phosphate buffer (10:90, v/v) and a flow rate of 0.8 ml.min-1 gave the most satisfactory separation of those vitamins using a UV detector set up at 204 nm and 220 nm. Detection limits ranged from 2.0 to 12.0 ?g.ml-1. When the method was applied to the determination of the vitamins, the found values were lower or close with those on the labels. The differences in the tablet contents of vitamins may be influenced by the kind of pharmaceutical preparation, by technical preparation making process and by the storage conditions.
dcterms:title
The determination of water soluble vitramins in multivitamin pharmaceutical preparations The determination of water soluble vitramins in multivitamin pharmaceutical preparations
skos:prefLabel
The determination of water soluble vitramins in multivitamin pharmaceutical preparations The determination of water soluble vitramins in multivitamin pharmaceutical preparations
skos:notation
RIV/70883521:28110/10:63509394!RIV11-MSM-28110___
n3:aktivita
n14:Z n14:I
n3:aktivity
I, Z(MSM7088352101)
n3:dodaniDat
n7:2011
n3:domaciTvurceVysledku
n5:7497768 n5:5711126 n5:7056974 n5:1800760 n5:9510087
n3:druhVysledku
n19:D
n3:duvernostUdaju
n12:S
n3:entitaPredkladatele
n9:predkladatel
n3:idSjednocenehoVysledku
253840
n3:idVysledku
RIV/70883521:28110/10:63509394
n3:jazykVysledku
n16:eng
n3:klicovaSlova
HPLC; thiamin; nicotinamide; pantothenic acid; pyridoxine; water soluble vitamin; pharmaceutical preparation
n3:klicoveSlovo
n4:thiamin n4:water%20soluble%20vitamin n4:nicotinamide n4:pyridoxine n4:HPLC n4:pantothenic%20acid n4:pharmaceutical%20preparation
n3:kontrolniKodProRIV
[B2E4DFDEC2D4]
n3:mistoKonaniAkce
Nitra
n3:mistoVydani
Nitra
n3:nazevZdroje
Bezpečnosť a kontrola potravín (Zborník prác z medzinárodnej vedeckej konferencie)
n3:obor
n20:GM
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
5
n3:rokUplatneniVysledku
n7:2010
n3:tvurceVysledku
Kramářová, Daniela Hoza, Ignác Rop, Otakar Altangerel, Bayanmunkh Kožáková, Zuzana
n3:typAkce
n11:EUR
n3:zahajeniAkce
2010-01-01+01:00
n3:zamer
n10:MSM7088352101
s:numberOfPages
5
n17:hasPublisher
Slovenská poľnohospodárska univerzita v Nitre
n21:isbn
978-80-552-0350-8
n15:organizacniJednotka
28110