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Statements

Subject Item
n2:RIV%2F68407700%3A21460%2F12%3A00202770%21RIV13-MSM-21460___
rdf:type
n14:Vysledek skos:Concept
dcterms:description
Hydrophobic substances (phthalocy anines) tend to aggregate in hydrophilic environment (bloodstream) and as a result they can lose their unique properties (photosensitivity). This can be overcome by encapsulating the substances into a drug delivery carrier, e.g. spheres from a biocompatible and biodegradable polymer. In thispaper polycaprolactone (PCL) spheres were synthetized by electrospraying, a method for preparation of polymeric micro- and nanospheres by high voltage application to a jet of polymer solution. The concentration dependence of PCL solution was investigated in the range of 1 % PCL solution to 10 % PCL solution. The samples were analyzed by scanning electron microscopy (SEM). The 7 % and 8 % PCL solutions seem to be the best concentration for PCL spheres preparation. Hydrophobic substances (phthalocy anines) tend to aggregate in hydrophilic environment (bloodstream) and as a result they can lose their unique properties (photosensitivity). This can be overcome by encapsulating the substances into a drug delivery carrier, e.g. spheres from a biocompatible and biodegradable polymer. In thispaper polycaprolactone (PCL) spheres were synthetized by electrospraying, a method for preparation of polymeric micro- and nanospheres by high voltage application to a jet of polymer solution. The concentration dependence of PCL solution was investigated in the range of 1 % PCL solution to 10 % PCL solution. The samples were analyzed by scanning electron microscopy (SEM). The 7 % and 8 % PCL solutions seem to be the best concentration for PCL spheres preparation.
dcterms:title
Synthesis of Polymeric Drug Carriers for Targeted Delivery of Bioactive Compounds Synthesis of Polymeric Drug Carriers for Targeted Delivery of Bioactive Compounds
skos:prefLabel
Synthesis of Polymeric Drug Carriers for Targeted Delivery of Bioactive Compounds Synthesis of Polymeric Drug Carriers for Targeted Delivery of Bioactive Compounds
skos:notation
RIV/68407700:21460/12:00202770!RIV13-MSM-21460___
n14:predkladatel
n15:orjk%3A21460
n3:aktivita
n4:P
n3:aktivity
P(EE.2.3.20.0092)
n3:dodaniDat
n8:2013
n3:domaciTvurceVysledku
n7:1025651 n7:8307318
n3:druhVysledku
n20:D
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
172984
n3:idVysledku
RIV/68407700:21460/12:00202770
n3:jazykVysledku
n21:eng
n3:klicovaSlova
bloodstream; photosensitivity; , diseased cells; , lipophilic substances
n3:klicoveSlovo
n12:photosensitivity n12:lipophilic%20substances n12:%20 n12:bloodstream n12:diseased%20cells
n3:kontrolniKodProRIV
[8A87D3EF66F4]
n3:mistoKonaniAkce
Kladno
n3:mistoVydani
Prague
n3:nazevZdroje
Instuments and Methods for Biology and Medicine 2012
n3:obor
n19:EB
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
4
n3:projekt
n10:EE.2.3.20.0092
n3:rokUplatneniVysledku
n8:2012
n3:tvurceVysledku
Vocetková, Karolína Jarošíková, Taťána Míčková, A. Buzgov, M.
n3:typAkce
n17:CST
n3:zahajeniAkce
2012-05-29+02:00
s:numberOfPages
4
n22:hasPublisher
České vysoké učení technické v Praze
n11:isbn
978-80-01-05119-1
n18:organizacniJednotka
21460