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Statements

Subject Item
n2:RIV%2F68407700%3A21460%2F11%3A00192486%21RIV12-MSM-21460___
rdf:type
n4:Vysledek skos:Concept
rdfs:seeAlso
http://imbm.fbmi.cvut.cz/soubory/sbornik.pdf
dcterms:description
Chitosan (CS) is a functional linear polysaccharide, which is prepared by partial N-deacetylation of chitin. Chitooligosaccharides (COS) can be produced by hydrolysis of CS. They exhibit various types of the potent biological activities useful for medical applications and health care. The changes in the bacterial population, followed by the shifts in the produced bacterial metabolites can significantly alter condition in gastrointestinal tract. In this in vivo study we modulated the changes of fecal bacteria population in healthy rats (groups: control, CS and COS) during administration of CS/COS. PCR-DGGE analysis was used to detect possible changes in bacterial population. The phylogenetic tree was also constructed. For the quantification of total and selected bacterial DNA was used real-time PCR analysis. CS/COS changed the composition of microbial ecosystem of gastrointestinal tract of healthy rats. Chitosan (CS) is a functional linear polysaccharide, which is prepared by partial N-deacetylation of chitin. Chitooligosaccharides (COS) can be produced by hydrolysis of CS. They exhibit various types of the potent biological activities useful for medical applications and health care. The changes in the bacterial population, followed by the shifts in the produced bacterial metabolites can significantly alter condition in gastrointestinal tract. In this in vivo study we modulated the changes of fecal bacteria population in healthy rats (groups: control, CS and COS) during administration of CS/COS. PCR-DGGE analysis was used to detect possible changes in bacterial population. The phylogenetic tree was also constructed. For the quantification of total and selected bacterial DNA was used real-time PCR analysis. CS/COS changed the composition of microbial ecosystem of gastrointestinal tract of healthy rats.
dcterms:title
The effect of chitosan and chitooligosaccharides on the fecal microbiota of healthy rats. The effect of chitosan and chitooligosaccharides on the fecal microbiota of healthy rats.
skos:prefLabel
The effect of chitosan and chitooligosaccharides on the fecal microbiota of healthy rats. The effect of chitosan and chitooligosaccharides on the fecal microbiota of healthy rats.
skos:notation
RIV/68407700:21460/11:00192486!RIV12-MSM-21460___
n4:predkladatel
n10:orjk%3A21460
n3:aktivita
n8:P
n3:aktivity
P(EE.2.3.20.0092)
n3:dodaniDat
n18:2012
n3:domaciTvurceVysledku
n9:8307318
n3:druhVysledku
n12:O
n3:duvernostUdaju
n19:S
n3:entitaPredkladatele
n6:predkladatel
n3:idSjednocenehoVysledku
196200
n3:idVysledku
RIV/68407700:21460/11:00192486
n3:jazykVysledku
n16:eng
n3:klicovaSlova
chitosan; fecal microbiota; PCR analysis
n3:klicoveSlovo
n13:fecal%20microbiota n13:PCR%20analysis n13:chitosan
n3:kontrolniKodProRIV
[2D28CDA31B20]
n3:obor
n17:EE
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
4
n3:projekt
n11:EE.2.3.20.0092
n3:rokUplatneniVysledku
n18:2011
n3:tvurceVysledku
Koppová, I. Jarošíková, Taťána Šimůnek, J. Bureš, M.
n7:organizacniJednotka
21460