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Statements

Subject Item
n2:RIV%2F68407700%3A21230%2F12%3A00198587%21RIV13-MSM-21230___
rdf:type
n8:Vysledek skos:Concept
dcterms:description
Matrix metalloproteinase-2 (MMP-2) and pregnancy-associated plasma protein-A (PAPP-A) have been implicated in chronic kidney disease (CKD) and cardiovascular disease (CVD). However, the serum determinants of MMP-2 and PAPP-A in CKD are unknown. The aim of the present study is to evaluate the clinical significance of MMP-2 and PAPP-A and their determinants in patients with CKD. The present study demonstrated that serum MMP-2 and PAPP-A were independent correlates of proteinuria, albumin, and other examined parameters. Our results suggest the possibility that circulating MMP-2 and PAPP-A be used as indicators for renal damage in CKD patients on conservative treatment. Matrix metalloproteinase-2 (MMP-2) and pregnancy-associated plasma protein-A (PAPP-A) have been implicated in chronic kidney disease (CKD) and cardiovascular disease (CVD). However, the serum determinants of MMP-2 and PAPP-A in CKD are unknown. The aim of the present study is to evaluate the clinical significance of MMP-2 and PAPP-A and their determinants in patients with CKD. The present study demonstrated that serum MMP-2 and PAPP-A were independent correlates of proteinuria, albumin, and other examined parameters. Our results suggest the possibility that circulating MMP-2 and PAPP-A be used as indicators for renal damage in CKD patients on conservative treatment.
dcterms:title
Determinants of Circulating Matrix Metalloproteinase-2 and Pregnancy-Associated Plasma Protein-A in Patients with Chronic Kidney Disease Determinants of Circulating Matrix Metalloproteinase-2 and Pregnancy-Associated Plasma Protein-A in Patients with Chronic Kidney Disease
skos:prefLabel
Determinants of Circulating Matrix Metalloproteinase-2 and Pregnancy-Associated Plasma Protein-A in Patients with Chronic Kidney Disease Determinants of Circulating Matrix Metalloproteinase-2 and Pregnancy-Associated Plasma Protein-A in Patients with Chronic Kidney Disease
skos:notation
RIV/68407700:21230/12:00198587!RIV13-MSM-21230___
n8:predkladatel
n17:orjk%3A21230
n3:aktivita
n15:I n15:S n15:V
n3:aktivity
I, S, V
n3:cisloPeriodika
5-6
n3:dodaniDat
n7:2013
n3:domaciTvurceVysledku
n18:7974051
n3:druhVysledku
n14:J
n3:duvernostUdaju
n4:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
130529
n3:idVysledku
RIV/68407700:21230/12:00198587
n3:jazykVysledku
n13:eng
n3:klicovaSlova
Matrix metalloproteinase-2; pregnancy-associated plasma protein-A; Chronic Kidney disease; proteinuria; albumin; anaemia
n3:klicoveSlovo
n10:proteinuria n10:Chronic%20Kidney%20disease n10:anaemia n10:pregnancy-associated%20plasma%20protein-A n10:albumin n10:Matrix%20metalloproteinase-2
n3:kodStatuVydavatele
DE - Spolková republika Německo
n3:kontrolniKodProRIV
[383503F1864C]
n3:nazevZdroje
CLINICAL LABORATORY
n3:obor
n5:FE
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
6
n3:rokUplatneniVysledku
n7:2012
n3:svazekPeriodika
58
n3:tvurceVysledku
Zakiyanov, O. Zima, T. Tesar, V. Kalousová, M. Kříha, Vítězslav Kratochvilová, M.
n3:wos
000305711100013
s:issn
1433-6510
s:numberOfPages
10
n12:organizacniJednotka
21230