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Statements

Subject Item
n2:RIV%2F68407700%3A21220%2F13%3A00213707%21RIV14-MSM-21220___
rdf:type
skos:Concept n19:Vysledek
rdfs:seeAlso
http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=6707382&tag=1
dcterms:description
Biological prostheses of human heart valves are prepared from autologous heart valves and from xenogeneic heart valves or pericardium. Xenogenous and allogenous biological prostheses are associated with adverse immune reactions, thrombosis and degeneration, and thus they have a high rate of reoperation. An optimum autologous tissue for heart valve grafts therefore needs to be found. Human pericardium was assessed as a potential source, and was compared with native human heart valves and porcine and bovine pericardium and heart valves. The tissues were evaluated for their mechanical properties, their collagen content and structure, and their histological structure. We observed differences in mechanical properties, collagen fibre orientation, the shape of the collagen bundles, and the collagen content among the pericardium samples and heart valves of different origin. Biological prostheses of human heart valves are prepared from autologous heart valves and from xenogeneic heart valves or pericardium. Xenogenous and allogenous biological prostheses are associated with adverse immune reactions, thrombosis and degeneration, and thus they have a high rate of reoperation. An optimum autologous tissue for heart valve grafts therefore needs to be found. Human pericardium was assessed as a potential source, and was compared with native human heart valves and porcine and bovine pericardium and heart valves. The tissues were evaluated for their mechanical properties, their collagen content and structure, and their histological structure. We observed differences in mechanical properties, collagen fibre orientation, the shape of the collagen bundles, and the collagen content among the pericardium samples and heart valves of different origin.
dcterms:title
Collagen structures in pericardium and aortic heart valves and their significance for tissue engineering Collagen structures in pericardium and aortic heart valves and their significance for tissue engineering
skos:prefLabel
Collagen structures in pericardium and aortic heart valves and their significance for tissue engineering Collagen structures in pericardium and aortic heart valves and their significance for tissue engineering
skos:notation
RIV/68407700:21220/13:00213707!RIV14-MSM-21220___
n19:predkladatel
n20:orjk%3A21220
n3:aktivita
n22:I
n3:aktivity
I
n3:dodaniDat
n21:2014
n3:domaciTvurceVysledku
n5:3615626 n5:2978458 n5:1885812 Chlup, Hynek n5:3776557
n3:druhVysledku
n7:D
n3:duvernostUdaju
n13:S
n3:entitaPredkladatele
n23:predkladatel
n3:idSjednocenehoVysledku
65917
n3:idVysledku
RIV/68407700:21220/13:00213707
n3:jazykVysledku
n6:eng
n3:klicovaSlova
aortic heart valve; collagen; mechanical properties; pericardium; second harmonic generation
n3:klicoveSlovo
n4:aortic%20heart%20valve n4:collagen n4:mechanical%20properties n4:second%20harmonic%20generation n4:pericardium
n3:kontrolniKodProRIV
[B958FF4FC046]
n3:mistoKonaniAkce
Iasi
n3:mistoVydani
Iasi
n3:nazevZdroje
4th IEEE International Conference on e-Health and Bioengineering EHB 2013
n3:obor
n12:EI
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
14
n3:rokUplatneniVysledku
n21:2013
n3:tvurceVysledku
Bačáková, L. Pirk, J. Hadraba, D. Horný, Lukáš Schorník, D. Staňková, L. Švindrych, Z. Chlup, Hynek Filová, E. Straka, F. Burdíková, Z. Žitný, Rudolf Gultová, Eva Veselý, Jan
n3:typAkce
n14:WRD
n3:zahajeniAkce
2013-11-21+01:00
s:numberOfPages
4
n17:doi
10.1109/EHB.2013.6707382
n15:hasPublisher
Gr. T. Popa University of Medicine and Pharmacy
n8:isbn
978-1-4799-2372-4
n11:organizacniJednotka
21220