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Statements

Subject Item
n2:RIV%2F68407700%3A21220%2F13%3A00210923%21RIV14-MSM-21220___
rdf:type
n12:Vysledek skos:Concept
dcterms:description
The inflation-extension test was performed in order to obtain the mechanical response (stress-strain curves) of vena saphena magna (usually used for coronary artery bypass graft surgery). Tubular samples of the vein were inflated four times up to the pressure approx. 4 kPa (vein pressure) and then four times up to approx. 16 kPa (systolic pressure). The experiments were recorded by the CCD camera. The longitudinal and circumferential deformations of the tube were evaluated using the edge detection method. The experimental data were fitted by anisotropic, nonlinear, constitutive model in order to obtain model parameters, especially the parameter which can be explain as collagen fibres orientation approximation. This parameter was then compared with the findings from histology. The histology analyses based on label-free imaging were performed additionally to the mechanical testing. Collagen (most important load-bearing component of the vein wall) was visualized using second harmonic generation. This method enabled us to observe collagen through the vein wall. It was found that the collagen fibres are helically aligned within the vein at an angle 37±6° measured from circumferential axis. The results show a high correlation between the arrangement of collagen obtained from histology and constitutive model. The inflation-extension test was performed in order to obtain the mechanical response (stress-strain curves) of vena saphena magna (usually used for coronary artery bypass graft surgery). Tubular samples of the vein were inflated four times up to the pressure approx. 4 kPa (vein pressure) and then four times up to approx. 16 kPa (systolic pressure). The experiments were recorded by the CCD camera. The longitudinal and circumferential deformations of the tube were evaluated using the edge detection method. The experimental data were fitted by anisotropic, nonlinear, constitutive model in order to obtain model parameters, especially the parameter which can be explain as collagen fibres orientation approximation. This parameter was then compared with the findings from histology. The histology analyses based on label-free imaging were performed additionally to the mechanical testing. Collagen (most important load-bearing component of the vein wall) was visualized using second harmonic generation. This method enabled us to observe collagen through the vein wall. It was found that the collagen fibres are helically aligned within the vein at an angle 37±6° measured from circumferential axis. The results show a high correlation between the arrangement of collagen obtained from histology and constitutive model.
dcterms:title
Inflation Test and Histology of Vena Saphena Magna Inflation Test and Histology of Vena Saphena Magna
skos:prefLabel
Inflation Test and Histology of Vena Saphena Magna Inflation Test and Histology of Vena Saphena Magna
skos:notation
RIV/68407700:21220/13:00210923!RIV14-MSM-21220___
n12:predkladatel
n13:orjk%3A21220
n3:aktivita
n4:P n4:S
n3:aktivity
P(NT13302), S
n3:dodaniDat
n15:2014
n3:domaciTvurceVysledku
n6:3615626 n6:2978458 n6:1885812 Chlup, Hynek
n3:druhVysledku
n17:D
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n20:predkladatel
n3:idSjednocenehoVysledku
79642
n3:idVysledku
RIV/68407700:21220/13:00210923
n3:jazykVysledku
n19:eng
n3:klicovaSlova
vena saphena; inflation-extension test; stress; histology; collagen; SHG
n3:klicoveSlovo
n8:inflation-extension%20test n8:collagen n8:stress n8:vena%20saphena n8:SHG n8:histology
n3:kontrolniKodProRIV
[AA04EE1936A1]
n3:mistoKonaniAkce
Litoměřice
n3:mistoVydani
Ústí nad Labem
n3:nazevZdroje
Proceedings of the 51st Conference on Experimental Stress Analysis
n3:obor
n14:BO
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
6
n3:projekt
n5:NT13302
n3:rokUplatneniVysledku
n15:2013
n3:tvurceVysledku
Chlup, Hynek Adámek, T. Hadraba, D. Žitný, Rudolf Veselý, Jan Horný, Lukáš
n3:typAkce
n22:EUR
n3:zahajeniAkce
2013-06-11+02:00
s:numberOfPages
6
n18:hasPublisher
FVTM,UJEP
n7:isbn
978-80-7414-579-7
n21:organizacniJednotka
21220