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Statements

Subject Item
n2:RIV%2F68378271%3A_____%2F13%3A00420820%21RIV14-MSM-68378271
rdf:type
skos:Concept n12:Vysledek
dcterms:description
The ultra short duration of laser-driven multi-MeV ion bursts offers the possibility of radiobiological studies at extremely high dose rates. Employing the TARANIS Terawatt laser at Queen’s University, the effect of proton irradiation at MeV-range energies on live cells has been investigated at dose rates exceeding 109 Gy/s as a single exposure. A clonogenic assay showed consistent lethal effects on V-79 live, cells, which, even at these dose rates, appear to be in line with previously published results employing conventional sources. A Relative Biological Effectiveness (RBE) of 1.40.2 at 10% survival is estimated from a comparison with a 225 kVp X-ray source. The ultra short duration of laser-driven multi-MeV ion bursts offers the possibility of radiobiological studies at extremely high dose rates. Employing the TARANIS Terawatt laser at Queen’s University, the effect of proton irradiation at MeV-range energies on live cells has been investigated at dose rates exceeding 109 Gy/s as a single exposure. A clonogenic assay showed consistent lethal effects on V-79 live, cells, which, even at these dose rates, appear to be in line with previously published results employing conventional sources. A Relative Biological Effectiveness (RBE) of 1.40.2 at 10% survival is estimated from a comparison with a 225 kVp X-ray source.
dcterms:title
First results on cell irradiation with laser-driven protons on the TARANIS system First results on cell irradiation with laser-driven protons on the TARANIS system
skos:prefLabel
First results on cell irradiation with laser-driven protons on the TARANIS system First results on cell irradiation with laser-driven protons on the TARANIS system
skos:notation
RIV/68378271:_____/13:00420820!RIV14-MSM-68378271
n12:predkladatel
n13:ico%3A68378271
n3:aktivita
n19:P n19:I
n3:aktivity
I, P(ED1.1.00/02.0061), P(EE.2.3.20.0087)
n3:dodaniDat
n6:2014
n3:domaciTvurceVysledku
Borghesi, Marco
n3:druhVysledku
n18:D
n3:duvernostUdaju
n7:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
75211
n3:idVysledku
RIV/68378271:_____/13:00420820
n3:jazykVysledku
n15:eng
n3:klicovaSlova
TARANIS Terawatt laser; proton irradiation; radiobiological studies; cells
n3:klicoveSlovo
n4:proton%20irradiation n4:TARANIS%20Terawatt%20laser n4:radiobiological%20studies n4:cells
n3:kontrolniKodProRIV
[C8B4B3ED452F]
n3:mistoKonaniAkce
Catania
n3:mistoVydani
Melville
n3:nazevZdroje
2nd ELIMED Workshop and Panel
n3:obor
n20:BL
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
18
n3:projekt
n8:EE.2.3.20.0087 n8:ED1.1.00%2F02.0061
n3:rokUplatneniVysledku
n6:2013
n3:tvurceVysledku
Jeynes, J.C.G. Lewis, C. Kirby, D. Prise, K. M. Ahmed, H. Prasad, R. Schettino, G. Kakolee, K. F. Litt, S. Fiorini, F. Green, S. Doria, D. Kar, S. Nersisyan, G. Kirkby, K. J. Zepf, M. Borghesi, Marco Merchant, M. J.
n3:typAkce
n9:WRD
n3:wos
000324289100013
n3:zahajeniAkce
2012-10-18+02:00
s:numberOfPages
3
n14:doi
10.1063/1.4816612
n17:hasPublisher
AIP
n21:isbn
978-0-7354-1171-5