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Statements

Subject Item
n2:RIV%2F68378050%3A_____%2F14%3A00442474%21RIV15-GA0-68378050
rdf:type
skos:Concept n16:Vysledek
dcterms:description
Aggregation of the high-affinity IgE receptor (Fc epsilon RI) on the plasma membrane of mast cells and basophils initiates signaling events leading to a rapid release of preformed inflammatory mediators from secretory granules, and overall changes in cell morphology. Mast cell activation also causes reorganization of cytoskeletal components associated with membrane ruffling, spreading, and migration. Here we describe methods used for visualization of mast cell cytoskeleton, focusing on its two major components, microfilaments and microtubules, and their changes after cell triggering. Aggregation of the high-affinity IgE receptor (Fc epsilon RI) on the plasma membrane of mast cells and basophils initiates signaling events leading to a rapid release of preformed inflammatory mediators from secretory granules, and overall changes in cell morphology. Mast cell activation also causes reorganization of cytoskeletal components associated with membrane ruffling, spreading, and migration. Here we describe methods used for visualization of mast cell cytoskeleton, focusing on its two major components, microfilaments and microtubules, and their changes after cell triggering.
dcterms:title
Membrane-Cytoskeleton Dynamics in the Course of Mast Cell Activation Membrane-Cytoskeleton Dynamics in the Course of Mast Cell Activation
skos:prefLabel
Membrane-Cytoskeleton Dynamics in the Course of Mast Cell Activation Membrane-Cytoskeleton Dynamics in the Course of Mast Cell Activation
skos:notation
RIV/68378050:_____/14:00442474!RIV15-GA0-68378050
n4:aktivita
n18:P n18:I
n4:aktivity
I, P(GA14-00703S), P(GA14-09807S), P(GA204/09/1777), P(GBP302/12/G101), P(KAN200520701), P(LC545), P(LD12073), P(LD13015)
n4:cisloPeriodika
September 2014
n4:dodaniDat
n5:2015
n4:domaciTvurceVysledku
n9:3093360 n9:5182581
n4:druhVysledku
n15:J
n4:duvernostUdaju
n6:S
n4:entitaPredkladatele
n11:predkladatel
n4:idSjednocenehoVysledku
28261
n4:idVysledku
RIV/68378050:_____/14:00442474
n4:jazykVysledku
n13:eng
n4:klicovaSlova
mast cells; plasma membrane; actin
n4:klicoveSlovo
n10:mast%20cells n10:actin n10:plasma%20membrane
n4:kodStatuVydavatele
US - Spojené státy americké
n4:kontrolniKodProRIV
[13C1B09A1D14]
n4:nazevZdroje
Methods in Molecular Biology
n4:obor
n17:EB
n4:pocetDomacichTvurcuVysledku
2
n4:pocetTvurcuVysledku
2
n4:projekt
n7:GA14-09807S n7:LD12073 n7:GA14-00703S n7:GA204%2F09%2F1777 n7:LC545 n7:LD13015 n7:GBP302%2F12%2FG101 n7:KAN200520701
n4:rokUplatneniVysledku
n5:2014
n4:svazekPeriodika
1220
n4:tvurceVysledku
Dráber, Petr Dráber, Pavel
n4:wos
000345968400015
s:issn
1064-3745
s:numberOfPages
19
n14:doi
10.1007/978-1-4939-1568-2