This HTML5 document contains 46 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n5http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n4http://linked.opendata.cz/resource/domain/vavai/projekt/
n17http://linked.opendata.cz/ontology/domain/vavai/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n15http://bibframe.org/vocab/
n8http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F68378050%3A_____%2F14%3A00434619%21RIV15-GA0-68378050/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n7http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n9http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n16http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n14http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n12http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n11http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n18http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F68378050%3A_____%2F14%3A00434619%21RIV15-GA0-68378050
rdf:type
n17:Vysledek skos:Concept
dcterms:description
Immunoglobulin E (IgE) first evolved in mammals. It plays an important role in defence against helminths and parasitic infection and in pathological states including allergic reactions, anti-tumour defence and autoimmune diseases. Elucidation of genetic control of IgE level could help us to understand regulation of the humoral immune response in health and disease, the etiology and pathogenesis of many human diseases, and to facilitate discovery of more effective methods for their prevention and cure. Herein we summarise progress in the genetics of regulation of IgE level in human diseases and show that integration of different approaches and use of animal models have synergistic effects in gaining new knowledge about both protective and pathological roles of this important antibody. Immunoglobulin E (IgE) first evolved in mammals. It plays an important role in defence against helminths and parasitic infection and in pathological states including allergic reactions, anti-tumour defence and autoimmune diseases. Elucidation of genetic control of IgE level could help us to understand regulation of the humoral immune response in health and disease, the etiology and pathogenesis of many human diseases, and to facilitate discovery of more effective methods for their prevention and cure. Herein we summarise progress in the genetics of regulation of IgE level in human diseases and show that integration of different approaches and use of animal models have synergistic effects in gaining new knowledge about both protective and pathological roles of this important antibody.
dcterms:title
Genetic regulation of immunoglobulin E level in different pathological states: integration of mouse and human genetics Genetic regulation of immunoglobulin E level in different pathological states: integration of mouse and human genetics
skos:prefLabel
Genetic regulation of immunoglobulin E level in different pathological states: integration of mouse and human genetics Genetic regulation of immunoglobulin E level in different pathological states: integration of mouse and human genetics
skos:notation
RIV/68378050:_____/14:00434619!RIV15-GA0-68378050
n3:aktivita
n14:I n14:P
n3:aktivity
I, P(GA310/08/1697), P(LH12049)
n3:cisloPeriodika
2
n3:dodaniDat
n18:2015
n3:domaciTvurceVysledku
n5:3714896 n5:5279097 n5:4745175 n5:6111122
n3:druhVysledku
n12:J
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n8:predkladatel
n3:idSjednocenehoVysledku
18101
n3:idVysledku
RIV/68378050:_____/14:00434619
n3:jazykVysledku
n16:eng
n3:klicovaSlova
Genetic control of complex diseases; Immunoglobulin E; Epistasis
n3:klicoveSlovo
n7:Immunoglobulin%20E n7:Genetic%20control%20of%20complex%20diseases n7:Epistasis
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[88742F7DEA70]
n3:nazevZdroje
Biological Reviews
n3:obor
n11:EB
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
4
n3:projekt
n4:GA310%2F08%2F1697 n4:LH12049
n3:rokUplatneniVysledku
n18:2014
n3:svazekPeriodika
89
n3:tvurceVysledku
Kurey, Irina Gusareva, Elena Lipoldová, Marie Grekov, Igor
n3:wos
000334182600007
s:issn
1464-7931
s:numberOfPages
31
n15:doi
10.1111/brv.12059