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Statements

Subject Item
n2:RIV%2F68378050%3A_____%2F01%3A23010304%21RIV%2F2003%2FAV0%2FA23003%2FN
rdf:type
skos:Concept n18:Vysledek
dcterms:description
Several of the CD98 antibodies induced homotypic aggregation of U937 cells without affecting cellular viability or growth. Some CD29 antibodies partially inhibited CD98-induced aggregation. Some CD98 antibodies were potent inhibitors of CD29-induced aggregation. Two antibodies to CD147 were also potent inhibitors of both the aggregation and the protein tyrosine phosphorylation induced via CD98 ligation. The results support a role for CD98 within a multimolecular unit that regulates cell aggregation. Several of the CD98 antibodies induced homotypic aggregation of U937 cells without affecting cellular viability or growth. Some CD29 antibodies partially inhibited CD98-induced aggregation. Some CD98 antibodies were potent inhibitors of CD29-induced aggregation. Two antibodies to CD147 were also potent inhibitors of both the aggregation and the protein tyrosine phosphorylation induced via CD98 ligation. The results support a role for CD98 within a multimolecular unit that regulates cell aggregation.
dcterms:title
The functional interactions between CD98, beta 1-integrins, and CD147 in the induction of U937 homotypic aggregation. The functional interactions between CD98, beta 1-integrins, and CD147 in the induction of U937 homotypic aggregation.
skos:prefLabel
The functional interactions between CD98, beta 1-integrins, and CD147 in the induction of U937 homotypic aggregation. The functional interactions between CD98, beta 1-integrins, and CD147 in the induction of U937 homotypic aggregation.
skos:notation
RIV/68378050:_____/01:23010304!RIV/2003/AV0/A23003/N
n4:strany
374;382
n4:aktivita
n8:Z n8:P
n4:aktivity
P(GA310/99/0349), Z(AV0Z5052915)
n4:cisloPeriodika
2
n4:dodaniDat
n14:2003
n4:domaciTvurceVysledku
n5:7776535
n4:druhVysledku
n11:J
n4:duvernostUdaju
n6:S
n4:entitaPredkladatele
n13:predkladatel
n4:idSjednocenehoVysledku
680821
n4:idVysledku
RIV/68378050:_____/01:23010304
n4:jazykVysledku
n10:eng
n4:klicovaSlova
integrin; - CD98; - CD147
n4:klicoveSlovo
n7:integrin n7:-%20CD147 n7:-%20CD98
n4:kodStatuVydavatele
US - Spojené státy americké
n4:kontrolniKodProRIV
[326B1C55B2A4]
n4:nazevZdroje
Blood
n4:obor
n9:EB
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
7
n4:pocetUcastnikuAkce
0
n4:pocetZahranicnichUcastnikuAkce
0
n4:projekt
n12:GA310%2F99%2F0349
n4:rokUplatneniVysledku
n14:2001
n4:svazekPeriodika
98
n4:tvurceVysledku
Katz, D. R. Sagawa, K. Fox, D. A. Cho, J. Y. Skubitz, K. M. Chain, B. Hořejší, Václav
n4:zamer
n17:AV0Z5052915
s:issn
0006-4971
s:numberOfPages
9