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Statements

Subject Item
n2:RIV%2F68378050%3A_____%2F00%3A23000254%21RIV%2F2003%2FAV0%2FA23003%2FN
rdf:type
n15:Vysledek skos:Concept
dcterms:description
We dissected genetic and functional aspects of susceptibility to leishmaniasis using two inbredstrains BALB/cHeA (susceptible) and STS/A (resistant) and a resistant Recombinant congenic strain CcS-5. Linkage analysis of F 2 hybrids between the strains BALB/c and CcS-5 revealed 5 novel Leishmaniamajor response ( Lmr) loci. Each of them affected a different subset of immunological and pathological parameters, indicating that different loci may contribute to the development of disease in different ways. We dissected genetic and functional aspects of susceptibility to leishmaniasis using two inbredstrains BALB/cHeA (susceptible) and STS/A (resistant) and a resistant Recombinant congenic strain CcS-5. Linkage analysis of F 2 hybrids between the strains BALB/c and CcS-5 revealed 5 novel Leishmaniamajor response ( Lmr) loci. Each of them affected a different subset of immunological and pathological parameters, indicating that different loci may contribute to the development of disease in different ways.
dcterms:title
Susceptibility to Leishmania major infection in mice: multiple loci and heterogeneity of immunopathological phenotypes. Susceptibility to Leishmania major infection in mice: multiple loci and heterogeneity of immunopathological phenotypes.
skos:prefLabel
Susceptibility to Leishmania major infection in mice: multiple loci and heterogeneity of immunopathological phenotypes. Susceptibility to Leishmania major infection in mice: multiple loci and heterogeneity of immunopathological phenotypes.
skos:notation
RIV/68378050:_____/00:23000254!RIV/2003/AV0/A23003/N
n4:strany
200;206
n4:aktivita
n11:Z n11:P
n4:aktivity
P(IZ4122), P(NM28), Z(AV0Z5052915)
n4:cisloPeriodika
3
n4:dodaniDat
n10:2003
n4:domaciTvurceVysledku
n9:9565612 n9:7092482 n9:6111122 n9:8506051 n9:5695678
n4:druhVysledku
n12:J
n4:duvernostUdaju
n18:S
n4:entitaPredkladatele
n7:predkladatel
n4:idSjednocenehoVysledku
728518
n4:idVysledku
RIV/68378050:_____/00:23000254
n4:jazykVysledku
n13:eng
n4:klicovaSlova
N/A
n4:klicoveSlovo
n16:N%2FA
n4:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n4:kontrolniKodProRIV
[AEC953FFDD28]
n4:nazevZdroje
Genes and Immunity
n4:obor
n8:EB
n4:pocetDomacichTvurcuVysledku
5
n4:pocetTvurcuVysledku
10
n4:pocetUcastnikuAkce
0
n4:pocetZahranicnichUcastnikuAkce
0
n4:projekt
n6:IZ4122 n6:NM28
n4:rokUplatneniVysledku
n10:2000
n4:svazekPeriodika
1
n4:tvurceVysledku
Lipoldová, Marie Badalová, Jana Holáň, Vladimír Nohýnková, E. Volf, P. Havelková, Helena Krulová, Magdalena Hart, A. Demant, P. Svobodová, M.
n4:zamer
n17:AV0Z5052915
s:issn
1466-4879
s:numberOfPages
7