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Statements

Subject Item
n2:RIV%2F68378050%3A_____%2F00%3A23000194%21RIV%2F2003%2FAV0%2FA23003%2FN
rdf:type
n14:Vysledek skos:Concept
dcterms:description
The intensity of lymphocyte reaction depends on the genetic differences between donors of the responding andstimulating cells. In mice, the strongest response is induced by the differences in the major histocompatibility complex (MHC) and Mls1 antigen. However, even with comparable differences in these antigens, some mousestrains respond better than other, which means that the intensity of this reaction can be influenced by other factors. Using the binding analysis of F2 hybrids between the strains ocB-9 and O20 carrying identical MHC antigens, we have identified a new locus Alan 2 (Alloantigen response 2) on chromosome 4, which controls the response to alloantigens C57L/10, BALB/c, and CBA. The intensity of lymphocyte reaction depends on the genetic differences between donors of the responding andstimulating cells. In mice, the strongest response is induced by the differences in the major histocompatibility complex (MHC) and Mls1 antigen. However, even with comparable differences in these antigens, some mousestrains respond better than other, which means that the intensity of this reaction can be influenced by other factors. Using the binding analysis of F2 hybrids between the strains ocB-9 and O20 carrying identical MHC antigens, we have identified a new locus Alan 2 (Alloantigen response 2) on chromosome 4, which controls the response to alloantigens C57L/10, BALB/c, and CBA.
dcterms:title
Induction of specific transplantation immunity by oral immunization with allongenic cells. Induction of specific transplantation immunity by oral immunization with allongenic cells.
skos:prefLabel
Induction of specific transplantation immunity by oral immunization with allongenic cells. Induction of specific transplantation immunity by oral immunization with allongenic cells.
skos:notation
RIV/68378050:_____/00:23000194!RIV/2003/AV0/A23003/N
n3:strany
404;411
n3:aktivita
n18:Z n18:P
n3:aktivity
P(GA310/97/1261), P(GA310/99/0360), P(GA310/99/D044), P(IZ3964), P(VS97099), Z(AV0Z5052915)
n3:cisloPeriodika
N/A
n3:dodaniDat
n15:2003
n3:domaciTvurceVysledku
n8:9565612 n8:7047118 n8:6947891 n8:5695678 n8:3755959
n3:druhVysledku
n6:J
n3:duvernostUdaju
n17:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
713434
n3:idVysledku
RIV/68378050:_____/00:23000194
n3:jazykVysledku
n4:eng
n3:klicovaSlova
N/A
n3:klicoveSlovo
n13:N%2FA
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[5CD2F06AB8C8]
n3:nazevZdroje
Immunology
n3:obor
n12:EB
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
6
n3:pocetUcastnikuAkce
0
n3:pocetZahranicnichUcastnikuAkce
0
n3:projekt
n7:GA310%2F97%2F1261 n7:GA310%2F99%2F0360 n7:IZ3964 n7:VS97099 n7:GA310%2F99%2FD044
n3:rokUplatneniVysledku
n15:2000
n3:svazekPeriodika
101
n3:tvurceVysledku
Krulová, Magdalena Frič, Jan Zajícová, Alena Plšková, Jarmila Filipec, M. Holáň, Vladimír
n3:zamer
n11:AV0Z5052915
s:issn
0019-2805
s:numberOfPages
8