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Statements

Subject Item
n2:RIV%2F68378041%3A_____%2F12%3A00383855%21RIV13-AV0-68378041
rdf:type
n15:Vysledek skos:Concept
dcterms:description
The present study has highlighted the mechanisms involved in Ca2+ homeostasis and Ca2+ clearance processes both in the cell bodies and the nerve terminals of the vasopressin (AVP) and oxytocin (OT) neurones in the supraoptic nucleus, using both the normal rat model and the recently developed transgenic rat with specific fluorescence labelling for AVP and OT. The physiological significance of the complexity of Ca2+ homeostatic mechanisms in the somatodendritic region of supraoptic neurones and their terminals can be multifaceted, attributable, in major part, to their specialized electrical activity and Ca2+-dependent neurohormone release. The present study has highlighted the mechanisms involved in Ca2+ homeostasis and Ca2+ clearance processes both in the cell bodies and the nerve terminals of the vasopressin (AVP) and oxytocin (OT) neurones in the supraoptic nucleus, using both the normal rat model and the recently developed transgenic rat with specific fluorescence labelling for AVP and OT. The physiological significance of the complexity of Ca2+ homeostatic mechanisms in the somatodendritic region of supraoptic neurones and their terminals can be multifaceted, attributable, in major part, to their specialized electrical activity and Ca2+-dependent neurohormone release.
dcterms:title
Segregation of calcium signalling mechanisms in magnocellular neurones and terminals Segregation of calcium signalling mechanisms in magnocellular neurones and terminals
skos:prefLabel
Segregation of calcium signalling mechanisms in magnocellular neurones and terminals Segregation of calcium signalling mechanisms in magnocellular neurones and terminals
skos:notation
RIV/68378041:_____/12:00383855!RIV13-AV0-68378041
n15:predkladatel
n16:ico%3A68378041
n3:aktivita
n8:P n8:Z
n3:aktivity
P(GAP303/11/0192), Z(AV0Z50390703)
n3:cisloPeriodika
3-4
n3:dodaniDat
n18:2013
n3:domaciTvurceVysledku
Verkhratsky, Alexei Forostyak, Oksana Dayanithi, Govindan
n3:druhVysledku
n6:J
n3:duvernostUdaju
n13:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
167239
n3:idVysledku
RIV/68378041:_____/12:00383855
n3:jazykVysledku
n4:eng
n3:klicovaSlova
Ca2+ stores; Mitochondria; Endoplasmic reticulum
n3:klicoveSlovo
n7:Endoplasmic%20reticulum n7:Mitochondria n7:Ca2%2B%20stores
n3:kodStatuVydavatele
DE - Spolková republika Německo
n3:kontrolniKodProRIV
[6F1414A0403D]
n3:nazevZdroje
Cell Calcium
n3:obor
n19:FH
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
5
n3:projekt
n12:GAP303%2F11%2F0192
n3:rokUplatneniVysledku
n18:2012
n3:svazekPeriodika
51
n3:tvurceVysledku
Verkhratsky, Alexei Dayanithi, Govindan Toescu, E. C. Ueta, Y. Forostyak, Oksana
n3:wos
000302443500011
n3:zamer
n5:AV0Z50390703
s:issn
0143-4160
s:numberOfPages
7
n9:doi
10.1016/j.ceca.2012.02.002