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Statements

Subject Item
n2:RIV%2F68378041%3A_____%2F12%3A00377767%21RIV13-AV0-68378041
rdf:type
n10:Vysledek skos:Concept
dcterms:description
We produced 2 different nanofiber-liposome systems in the present study: liposomes blended within nanofibers and core/shell nanofibers with embedded liposomes. We demonstrate that blend electrospinning does not conserve intact liposomes in contrast to coaxial electrospinning which enables the incorporation of liposomes into nanofibers. We report polyvinyl alcohol-core/poly-ε-caprolactone-shell nanofibers with embedded liposomes and show that they preserve the enzymatic activity of encapsulated horseradish peroxidase. The potential of this system was also demonstrated by the enhancement of mesenchymal stem cell proliferation. We produced 2 different nanofiber-liposome systems in the present study: liposomes blended within nanofibers and core/shell nanofibers with embedded liposomes. We demonstrate that blend electrospinning does not conserve intact liposomes in contrast to coaxial electrospinning which enables the incorporation of liposomes into nanofibers. We report polyvinyl alcohol-core/poly-ε-caprolactone-shell nanofibers with embedded liposomes and show that they preserve the enzymatic activity of encapsulated horseradish peroxidase. The potential of this system was also demonstrated by the enhancement of mesenchymal stem cell proliferation.
dcterms:title
Core/Shell Nanofibers with Embedded Liposomes as a Drug Delivery System Core/Shell Nanofibers with Embedded Liposomes as a Drug Delivery System
skos:prefLabel
Core/Shell Nanofibers with Embedded Liposomes as a Drug Delivery System Core/Shell Nanofibers with Embedded Liposomes as a Drug Delivery System
skos:notation
RIV/68378041:_____/12:00377767!RIV13-AV0-68378041
n10:predkladatel
n20:ico%3A68378041
n3:aktivita
n4:S n4:P n4:I n4:Z
n3:aktivity
I, P(1M0510), P(2B06130), P(GA202/09/1151), P(GAP304/10/1307), P(IAA500390702), P(NT12156), S, Z(AV0Z50200510), Z(AV0Z50390512), Z(AV0Z50390703), Z(AV0Z60220518), Z(MSM0021620849)
n3:cisloPeriodika
4
n3:dodaniDat
n11:2013
n3:domaciTvurceVysledku
n7:1304992 Míčková, Andrea Filová, Eva n7:3458830 Buzgo, Matej
n3:druhVysledku
n8:J
n3:duvernostUdaju
n16:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
128801
n3:idVysledku
RIV/68378041:_____/12:00377767
n3:jazykVysledku
n13:eng
n3:klicovaSlova
tissue Engineering applications; electrospun nanofibers; liposomes
n3:klicoveSlovo
n6:tissue%20Engineering%20applications n6:electrospun%20nanofibers n6:liposomes
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[A53C784BFCD7]
n3:nazevZdroje
Biomacromolecules
n3:obor
n19:FP
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
9
n3:projekt
n5:IAA500390702 n5:2B06130 n5:1M0510 n5:GAP304%2F10%2F1307 n5:NT12156 n5:GA202%2F09%2F1151
n3:rokUplatneniVysledku
n11:2012
n3:svazekPeriodika
13
n3:tvurceVysledku
Lukáš, D. Buzgo, Matej Benada, Oldřich Míčková, Andrea Amler, Evžen Rampichová, Michala Tesařová, Martina Filová, Eva Fišar, Z.
n3:wos
000303076200002
n3:zamer
n15:AV0Z60220518 n15:AV0Z50200510 n15:MSM0021620849 n15:AV0Z50390703 n15:AV0Z50390512
s:issn
1525-7797
s:numberOfPages
11
n18:doi
10.1021/bm2018118