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Statements

Subject Item
n2:RIV%2F68378041%3A_____%2F12%3A00375923%21RIV13-AV0-68378041
rdf:type
n16:Vysledek skos:Concept
dcterms:description
Sodium hyaluronate (HA) was associated with dopamine (DPA) and introduced as a coating for maghemite (γ-Fe2O3) nanoparticles obtained by the coprecipitation of iron(II) and iron(III) chlorides and oxidation with sodium hypochlorite. The effects of the DPA anchorage of HA on the γ-Fe2O3 surface on the physicochemical properties of the resulting colloids were investigated. Nanoparticles coated at three different DPA-HA/γ-Fe2O3 and DPA/HA ratios were chosen for experiments with rat bone marrow mesenchymal stem cells and human chondrocytes. The efficiency of mesenchymal stem cell labeling was analyzed. From among the investigated samples, efficient cell labeling was achieved by using DPA-HA-γ-Fe2O3 nanoparticles with DPA-HA/γ-Fe2O3 = 0.45 (weight/weight) and DPA/HA = 0.038 (weight/weight) ratios. The particles were used as a contrast agent in magnetic resonance imaging for the labeling and visualization of cells. Sodium hyaluronate (HA) was associated with dopamine (DPA) and introduced as a coating for maghemite (γ-Fe2O3) nanoparticles obtained by the coprecipitation of iron(II) and iron(III) chlorides and oxidation with sodium hypochlorite. The effects of the DPA anchorage of HA on the γ-Fe2O3 surface on the physicochemical properties of the resulting colloids were investigated. Nanoparticles coated at three different DPA-HA/γ-Fe2O3 and DPA/HA ratios were chosen for experiments with rat bone marrow mesenchymal stem cells and human chondrocytes. The efficiency of mesenchymal stem cell labeling was analyzed. From among the investigated samples, efficient cell labeling was achieved by using DPA-HA-γ-Fe2O3 nanoparticles with DPA-HA/γ-Fe2O3 = 0.45 (weight/weight) and DPA/HA = 0.038 (weight/weight) ratios. The particles were used as a contrast agent in magnetic resonance imaging for the labeling and visualization of cells.
dcterms:title
The use of dopamine-hyaluronate associate-coated maghemite nanoparticles to label cells The use of dopamine-hyaluronate associate-coated maghemite nanoparticles to label cells
skos:prefLabel
The use of dopamine-hyaluronate associate-coated maghemite nanoparticles to label cells The use of dopamine-hyaluronate associate-coated maghemite nanoparticles to label cells
skos:notation
RIV/68378041:_____/12:00375923!RIV13-AV0-68378041
n16:predkladatel
n18:ico%3A68378041
n3:aktivita
n11:P n11:I n11:Z
n3:aktivity
I, P(1M0538), P(GA203/09/1242), P(GAP304/12/1370), P(GCP207/12/J013), Z(AV0Z40500505), Z(AV0Z50390703)
n3:cisloPeriodika
16 March
n3:dodaniDat
n17:2013
n3:domaciTvurceVysledku
n6:6220533 n6:6738109 n6:4798201 n6:1894803
n3:druhVysledku
n8:J
n3:duvernostUdaju
n20:S
n3:entitaPredkladatele
n19:predkladatel
n3:idSjednocenehoVysledku
176342
n3:idVysledku
RIV/68378041:_____/12:00375923
n3:jazykVysledku
n14:eng
n3:klicovaSlova
nanoparticles; dopamine; hyaluronate
n3:klicoveSlovo
n7:nanoparticles n7:hyaluronate n7:dopamine
n3:kodStatuVydavatele
NZ - Nový Zéland
n3:kontrolniKodProRIV
[ADC441F00D96]
n3:nazevZdroje
International Journal of Nanomedicine
n3:obor
n15:FH
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
8
n3:projekt
n9:GA203%2F09%2F1242 n9:GCP207%2F12%2FJ013 n9:GAP304%2F12%2F1370 n9:1M0538
n3:rokUplatneniVysledku
n17:2012
n3:svazekPeriodika
7
n3:tvurceVysledku
Jendelová, Pavla Proks, Vladimír Vaněček, Václav Syková, Eva Horák, Daniel Herynek, V. Lesný, Petr Babič, Michal
n3:wos
000302728100001
n3:zamer
n5:AV0Z40500505 n5:AV0Z50390703
s:issn
1178-2013
s:numberOfPages
14
n12:doi
10.2147/IJN.S28658