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Statements

Subject Item
n2:RIV%2F68378041%3A_____%2F11%3A00368699%21RIV12-AV0-68378041
rdf:type
n10:Vysledek skos:Concept
dcterms:description
Here, we have performed a preliminary mapping of serotonergic processes and serotonin-lA (5-HT(1A)) receptors in thoracic and lumbar segments of the human spinal cord. 5-HT profiles in human spinal cord are present in the ventral horn, surrounding motoneurons, and also contact their presumptive dendrites at lumbar level. 5-HT(1A) receptors are present in the same area, but are more densely expressed at lumbar level. These findings pave the way for local specific therapies involving cellular and/or pharmacological tools targeting the serotonergic system. Here, we have performed a preliminary mapping of serotonergic processes and serotonin-lA (5-HT(1A)) receptors in thoracic and lumbar segments of the human spinal cord. 5-HT profiles in human spinal cord are present in the ventral horn, surrounding motoneurons, and also contact their presumptive dendrites at lumbar level. 5-HT(1A) receptors are present in the same area, but are more densely expressed at lumbar level. These findings pave the way for local specific therapies involving cellular and/or pharmacological tools targeting the serotonergic system.
dcterms:title
Anatomical study of serotonergic innervation and 5-HT(1A) receptor in the human spinal cord Anatomical study of serotonergic innervation and 5-HT(1A) receptor in the human spinal cord
skos:prefLabel
Anatomical study of serotonergic innervation and 5-HT(1A) receptor in the human spinal cord Anatomical study of serotonergic innervation and 5-HT(1A) receptor in the human spinal cord
skos:notation
RIV/68378041:_____/11:00368699!RIV12-AV0-68378041
n10:predkladatel
n11:ico%3A68378041
n3:aktivita
n14:Z n14:P
n3:aktivity
P(GA309/09/1696), P(GAP304/11/0184), Z(AV0Z50390703)
n3:cisloPeriodika
-
n3:dodaniDat
n4:2012
n3:domaciTvurceVysledku
Rodriguez Arellano, Jose Julio
n3:druhVysledku
n15:J
n3:duvernostUdaju
n13:S
n3:entitaPredkladatele
n18:predkladatel
n3:idSjednocenehoVysledku
186225
n3:idVysledku
RIV/68378041:_____/11:00368699
n3:jazykVysledku
n6:eng
n3:klicovaSlova
genito-urinary tract; locomotion; nociceptive pathway
n3:klicoveSlovo
n5:locomotion n5:genito-urinary%20tract n5:nociceptive%20pathway
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[F61725A5965B]
n3:nazevZdroje
Cell Death & Disease
n3:obor
n19:FH
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
9
n3:projekt
n9:GAP304%2F11%2F0184 n9:GA309%2F09%2F1696
n3:rokUplatneniVysledku
n4:2011
n3:svazekPeriodika
2
n3:tvurceVysledku
Hugnot, J. P. Gerber, Y. N. Privat, A. M. Lonjon, N. Rodriguez Arellano, Jose Julio Teigell, M. Perrin, F. E. Bauchet, L. Boniface, G.
n3:wos
000296587500007
n3:zamer
n7:AV0Z50390703
s:issn
2041-4889
s:numberOfPages
6
n17:doi
10.1038/cddis.2011.98