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Statements

Subject Item
n2:RIV%2F68378041%3A_____%2F08%3A00317731%21RIV09-AV0-68378041
rdf:type
n8:Vysledek skos:Concept
dcterms:description
Studovali jsme expresi ARG3.1/ARC v astrocytech gyrus dentatus v hippokamu, abychom určili lokalizaci a vnitrubuněčnou distribuci Arg3.1/Arc proteinu v GFAP pozitivních gliových buňkách. Naše pokusy prokázaly, že Arg3.1/Arc-IR v astrocytech se po indukci LTP zvyšuje a naznačují tak, že gliální Arg3.1/Arc hraje důležitou úlohu v strukturální a synaptické plasticitě, která může být kritickým faktorem pro udržování kognitivních funkcí. We have investigated ARG3.1/ARC expression in hippocampal dentate gyrus astrocytes to determine the localization and sub-cellular distribution of Arg3.1/Arc protein in GFAP positive glia. Our data, taken with our earlier study which provided evidence for an increase in astrocytic Arg3.1/Arc-IR after the induction of LTP, suggest a role for glial Arg3.1/Arc in structural and synaptic plasticity which may be critical for the maintenance of cognitive functions. We have investigated ARG3.1/ARC expression in hippocampal dentate gyrus astrocytes to determine the localization and sub-cellular distribution of Arg3.1/Arc protein in GFAP positive glia. Our data, taken with our earlier study which provided evidence for an increase in astrocytic Arg3.1/Arc-IR after the induction of LTP, suggest a role for glial Arg3.1/Arc in structural and synaptic plasticity which may be critical for the maintenance of cognitive functions.
dcterms:title
ARG3.1/ARC exprese v astrocytech gyrus dentatus v hippokamu: ultrastrukturální průkaz a ko-lokalizace s gliálním fibrilárním kyselým proteinem ARG3.1/ARC expression in hippocampal dentate gyrus astrocytes: ultrastructural evidence and co-localization with glial fibrillary acidic protein ARG3.1/ARC expression in hippocampal dentate gyrus astrocytes: ultrastructural evidence and co-localization with glial fibrillary acidic protein
skos:prefLabel
ARG3.1/ARC expression in hippocampal dentate gyrus astrocytes: ultrastructural evidence and co-localization with glial fibrillary acidic protein ARG3.1/ARC expression in hippocampal dentate gyrus astrocytes: ultrastructural evidence and co-localization with glial fibrillary acidic protein ARG3.1/ARC exprese v astrocytech gyrus dentatus v hippokamu: ultrastrukturální průkaz a ko-lokalizace s gliálním fibrilárním kyselým proteinem
skos:notation
RIV/68378041:_____/08:00317731!RIV09-AV0-68378041
n3:aktivita
n4:Z
n3:aktivity
Z(AV0Z50390512)
n3:cisloPeriodika
2
n3:dodaniDat
n14:2009
n3:domaciTvurceVysledku
Verkhratsky, Alexei
n3:druhVysledku
n12:J
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n6:predkladatel
n3:idSjednocenehoVysledku
357010
n3:idVysledku
RIV/68378041:_____/08:00317731
n3:jazykVysledku
n16:eng
n3:klicovaSlova
Hippocampus; Ultrastructure; Glia
n3:klicoveSlovo
n11:Glia n11:Ultrastructure n11:Hippocampus
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[16CE676420F7]
n3:nazevZdroje
Journal of Cellular and Molecular Medicine
n3:obor
n7:FH
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
6
n3:rokUplatneniVysledku
n14:2008
n3:svazekPeriodika
12
n3:tvurceVysledku
Errington, M. L. Davies, H. A. Rodríguez, J. J. Verkhratsky, Alexei Stewart, M. G. Bliss, T.V.P.
n3:wos
255060600023
n3:zamer
n15:AV0Z50390512
s:issn
1582-1838
s:numberOfPages
8