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Statements

Subject Item
n2:RIV%2F68378041%3A_____%2F03%3A19033057%21RIV%2F2004%2FAV0%2FA19004%2FN
rdf:type
skos:Concept n12:Vysledek
dcterms:description
It was shown that while the majority of human leukemia and lymphoma cell lines synthesizes low molecular mass FGF-2, its release is generally insufficient. However, several cell lines display prerequisites to respond to the extracellular FGF-2 that could be produced by other cell types. Importantly, in a majority of cell lines was found concomitant expression of two potent antiapoptotic molecules, high molecular mass FGF-2 and FGF-2-interacting protein FIF. This opens the possibility of their participation in the regulation of apoptosis. It was shown that while the majority of human leukemia and lymphoma cell lines synthesizes low molecular mass FGF-2, its release is generally insufficient. However, several cell lines display prerequisites to respond to the extracellular FGF-2 that could be produced by other cell types. Importantly, in a majority of cell lines was found concomitant expression of two potent antiapoptotic molecules, high molecular mass FGF-2 and FGF-2-interacting protein FIF. This opens the possibility of their participation in the regulation of apoptosis.
dcterms:title
FGF-2 expression and its action in human leukemia and lymphoma cell lines. FGF-2 expression and its action in human leukemia and lymphoma cell lines.
skos:prefLabel
FGF-2 expression and its action in human leukemia and lymphoma cell lines. FGF-2 expression and its action in human leukemia and lymphoma cell lines.
skos:notation
RIV/68378041:_____/03:19033057!RIV/2004/AV0/A19004/N
n3:strany
818;820
n3:aktivita
n15:Z n15:P
n3:aktivity
P(LN00A065), P(ME 198), Z(AV0Z5039906), Z(MSM 432100001)
n3:cisloPeriodika
N/A
n3:dodaniDat
n17:2004
n3:domaciTvurceVysledku
n7:4001818 n7:9569707 n7:8064296
n3:druhVysledku
n18:J
n3:duvernostUdaju
n14:S
n3:entitaPredkladatele
n5:predkladatel
n3:idSjednocenehoVysledku
607213
n3:idVysledku
RIV/68378041:_____/03:19033057
n3:jazykVysledku
n4:eng
n3:klicovaSlova
leukemia
n3:klicoveSlovo
n16:leukemia
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[F94E8100BE05]
n3:nazevZdroje
Leukemia
n3:obor
n13:EB
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
5
n3:pocetUcastnikuAkce
0
n3:pocetZahranicnichUcastnikuAkce
0
n3:projekt
n6:ME%20198 n6:LN00A065
n3:rokUplatneniVysledku
n17:2003
n3:svazekPeriodika
17
n3:tvurceVysledku
Faitová, Jitka Dvořák, Petr Laurell, H. Krejčí, P. Hampl, Aleš
n3:zamer
n10:AV0Z5039906 n10:MSM%20432100001
s:issn
0887-6924
s:numberOfPages
3