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Statements

Subject Item
n2:RIV%2F68081766%3A_____%2F12%3A00390442%21RIV13-GA0-68081766
rdf:type
skos:Concept n16:Vysledek
dcterms:description
Digitization of periosteal and endosteal contours of bone cross section is one of several methods used for calculating long bone cross-sectional geometry (CSG). In this study, invasively obtained bone histological samples were used to calculate intra-observer measurement error for CSG parameters. Intra-observer error was measured based upon repeated measurements of cross-sectional areas (total area [TA], cortical area [CA]) and moments of area (I-max, I-min, I-max/I-min, J) in B6CBA mice (n = 17). Cross sections were cut at 50 % of the biomechanical length of the left tibia and the samples were further processed for CSG and histological analysis. Intra-observer error was measured to estimate the accuracy of the digitization method. Accuracy of the tested digitization method was expressed by mean difference (MD), mean absolute difference (MAD), and limits of agreement (LA). The results confirm our assumption that intra-observer error decreases with the number of repeated measurement events. Thus, the error can be minimized by acquiring experience in the section digitizing. Our results also show that TA, CA and polar moment of area (J) are more susceptible to intra-observer error than are I-max, I-min and I-max/I-min. Digitization of periosteal and endosteal contours of bone cross section is one of several methods used for calculating long bone cross-sectional geometry (CSG). In this study, invasively obtained bone histological samples were used to calculate intra-observer measurement error for CSG parameters. Intra-observer error was measured based upon repeated measurements of cross-sectional areas (total area [TA], cortical area [CA]) and moments of area (I-max, I-min, I-max/I-min, J) in B6CBA mice (n = 17). Cross sections were cut at 50 % of the biomechanical length of the left tibia and the samples were further processed for CSG and histological analysis. Intra-observer error was measured to estimate the accuracy of the digitization method. Accuracy of the tested digitization method was expressed by mean difference (MD), mean absolute difference (MAD), and limits of agreement (LA). The results confirm our assumption that intra-observer error decreases with the number of repeated measurement events. Thus, the error can be minimized by acquiring experience in the section digitizing. Our results also show that TA, CA and polar moment of area (J) are more susceptible to intra-observer error than are I-max, I-min and I-max/I-min.
dcterms:title
Intra-observer error of mouse long bone cross section digitization Intra-observer error of mouse long bone cross section digitization
skos:prefLabel
Intra-observer error of mouse long bone cross section digitization Intra-observer error of mouse long bone cross section digitization
skos:notation
RIV/68081766:_____/12:00390442!RIV13-GA0-68081766
n16:predkladatel
n18:ico%3A68081766
n3:aktivita
n10:I n10:S n10:P
n3:aktivity
I, P(GA206/09/0589), S
n3:cisloPeriodika
3-4
n3:dodaniDat
n8:2013
n3:domaciTvurceVysledku
n7:2637650
n3:druhVysledku
n13:J
n3:duvernostUdaju
n6:S
n3:entitaPredkladatele
n15:predkladatel
n3:idSjednocenehoVysledku
142758
n3:idVysledku
RIV/68081766:_____/12:00390442
n3:jazykVysledku
n17:eng
n3:klicovaSlova
accuracy; cortical bone; CSG; digitization; tibia
n3:klicoveSlovo
n9:digitization n9:cortical%20bone n9:accuracy n9:tibia n9:CSG
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[643AAB5F0242]
n3:nazevZdroje
Folia zoologica
n3:obor
n14:EG
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
3
n3:projekt
n11:GA206%2F09%2F0589
n3:rokUplatneniVysledku
n8:2012
n3:svazekPeriodika
61
n3:tvurceVysledku
Tůma, J. Jindrová, A. Sládek, Vladimír
n3:wos
000313606500015
s:issn
0139-7893
s:numberOfPages
10