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Statements

Subject Item
n2:RIV%2F68081766%3A_____%2F10%3A00337970%21RIV11-AV0-68081766
rdf:type
n9:Vysledek skos:Concept
dcterms:description
We examine the temporal changes in ovarian function in a large sample of infertile patients from the Czech Republic over a period of 14 years. In a retrospective study, we analysed a large body of data from women, 20-40 years of age, undergoing IVF/ICSI treatment between 1995 and 2008. We defined ovarian function using five variables: basal FSH level, estradiol (E2) level on the day of HCG administration, dose of gonadotrophins used for ovarian stimulation, number of retrieved oocytes and dose of gonadotrophins per oocyte. Controlling simultaneously for temporal changes in patient age and stimulation protocol, we applied generalized additive models to describe the temporal trends. The results are indicative of a small, but detectable decrease in ovarian function over a period of 14 years, which is not causally related to the ageing population. We examine the temporal changes in ovarian function in a large sample of infertile patients from the Czech Republic over a period of 14 years. In a retrospective study, we analysed a large body of data from women, 20-40 years of age, undergoing IVF/ICSI treatment between 1995 and 2008. We defined ovarian function using five variables: basal FSH level, estradiol (E2) level on the day of HCG administration, dose of gonadotrophins used for ovarian stimulation, number of retrieved oocytes and dose of gonadotrophins per oocyte. Controlling simultaneously for temporal changes in patient age and stimulation protocol, we applied generalized additive models to describe the temporal trends. The results are indicative of a small, but detectable decrease in ovarian function over a period of 14 years, which is not causally related to the ageing population.
dcterms:title
Is there a declining trend in ovarian function among infertility clinic patients? Is there a declining trend in ovarian function among infertility clinic patients?
skos:prefLabel
Is there a declining trend in ovarian function among infertility clinic patients? Is there a declining trend in ovarian function among infertility clinic patients?
skos:notation
RIV/68081766:_____/10:00337970!RIV11-AV0-68081766
n3:aktivita
n16:Z n16:S
n3:aktivity
S, Z(AV0Z60930519), Z(MSM6198959212)
n3:cisloPeriodika
1
n3:dodaniDat
n5:2011
n3:domaciTvurceVysledku
n14:7996144
n3:druhVysledku
n7:J
n3:duvernostUdaju
n15:S
n3:entitaPredkladatele
n12:predkladatel
n3:idSjednocenehoVysledku
264980
n3:idVysledku
RIV/68081766:_____/10:00337970
n3:jazykVysledku
n6:eng
n3:klicovaSlova
ovarian function; decrease; infertility; IVF
n3:klicoveSlovo
n11:IVF n11:ovarian%20function n11:infertility n11:decrease
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[6BB59C7D65CC]
n3:nazevZdroje
Human Reproduction
n3:obor
n17:FK
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
4
n3:rokUplatneniVysledku
n5:2010
n3:svazekPeriodika
25
n3:tvurceVysledku
Sobek, A. Tkadlec, Emil Hladíková, B. Sobek Jr., A.
n3:wos
000272929600019
n3:zamer
n10:MSM6198959212 n10:AV0Z60930519
s:issn
0268-1161
s:numberOfPages
6