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Statements

Subject Item
n2:RIV%2F68081731%3A_____%2F12%3A00385359%21RIV13-AV0-68081731
rdf:type
n3:Vysledek skos:Concept
dcterms:description
Multipass dynamic MRI and pharmacokinetic modeling are used to estimate perfusion parameters of leaky capillaries. Curve fitting and nonblind deconvolution are the established methods to derive the perfusion estimates from the observed arterial input function (AIF) and tissue tracer concentration function. These nonblind methods are sensitive to errors in the AIF, measured in some nearby artery or estimated by multichannel blind deconvolution. Here, a single-channel blind deconvolution algorithm is presented, which only uses a single tissue tracer concentration function to estimate the corresponding AIF and tissue impulse response function. That way, many errors affecting these functions are reduced. The validity of the algorithm is supported by simulations and tests on real data from mouse. The corresponding nonblind and multichannel methods are also presented. Multipass dynamic MRI and pharmacokinetic modeling are used to estimate perfusion parameters of leaky capillaries. Curve fitting and nonblind deconvolution are the established methods to derive the perfusion estimates from the observed arterial input function (AIF) and tissue tracer concentration function. These nonblind methods are sensitive to errors in the AIF, measured in some nearby artery or estimated by multichannel blind deconvolution. Here, a single-channel blind deconvolution algorithm is presented, which only uses a single tissue tracer concentration function to estimate the corresponding AIF and tissue impulse response function. That way, many errors affecting these functions are reduced. The validity of the algorithm is supported by simulations and tests on real data from mouse. The corresponding nonblind and multichannel methods are also presented.
dcterms:title
Single-Channel Blind Estimation of Arterial Input Function and Tissue Impulse Response in DCE-MRI Single-Channel Blind Estimation of Arterial Input Function and Tissue Impulse Response in DCE-MRI
skos:prefLabel
Single-Channel Blind Estimation of Arterial Input Function and Tissue Impulse Response in DCE-MRI Single-Channel Blind Estimation of Arterial Input Function and Tissue Impulse Response in DCE-MRI
skos:notation
RIV/68081731:_____/12:00385359!RIV13-AV0-68081731
n3:predkladatel
n13:ico%3A68081731
n4:aktivita
n9:S n9:P n9:I
n4:aktivity
I, P(GA102/09/1690), S
n4:cisloPeriodika
4
n4:dodaniDat
n17:2013
n4:domaciTvurceVysledku
n10:1352717
n4:druhVysledku
n6:J
n4:duvernostUdaju
n19:S
n4:entitaPredkladatele
n5:predkladatel
n4:idSjednocenehoVysledku
168133
n4:idVysledku
RIV/68081731:_____/12:00385359
n4:jazykVysledku
n15:eng
n4:klicovaSlova
arterial input function (AIF); blind deconvolution; dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI); multichannel; perfusion; single channel
n4:klicoveSlovo
n7:blind%20deconvolution n7:perfusion n7:arterial%20input%20function%20%28AIF%29 n7:dynamic%20contrast-enhanced%20magnetic%20resonance%20imaging%20%28DCE-MRI%29 n7:multichannel n7:single%20channel
n4:kodStatuVydavatele
US - Spojené státy americké
n4:kontrolniKodProRIV
[FEC69E116F03]
n4:nazevZdroje
IEEE Transactions on Biomedical Engineering
n4:obor
n11:BH
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
8
n4:projekt
n18:GA102%2F09%2F1690
n4:rokUplatneniVysledku
n17:2012
n4:svazekPeriodika
59
n4:tvurceVysledku
Rygh, C. B. Grüner, R. Reed, R. K. Taxt, T. Jiřík, Radovan Bartoš, M. Curry, F. R. Andersen, E.
n4:wos
000302175300013
s:issn
0018-9294
s:numberOfPages
10
n8:doi
10.1109/TBME.2011.2182195